scholarly journals Malignant Melanoma of Anal Canal

2021 ◽  
Vol 5 (1) ◽  
pp. 57-59
Author(s):  
Ishan Dhungana ◽  
Ranjan Raj Bhatta ◽  
Greta Pandey ◽  
Suraj Upreti ◽  
Nadita Shah ◽  
...  

Anal melanoma (AM) is a rare and highly aggressive mucosal melanocytic malignancy. We report a case of 70 year old male presented with chief complaints of anal pain and intermittent rectal bleeding with clinical diagnosis of Polyp or Carcinoma. On histopathology examination malignant melanoma was suggested which was further confirmed by immunohistochemistry (S100 and HMB 45 strongly positive). Anal melanoma is rare neoplastic condition with catastrophic outcome.   

2014 ◽  
Vol 4 ◽  
pp. 4 ◽  
Author(s):  
Supreethi Kohli ◽  
Seema Narang ◽  
Anu Singhal ◽  
Vinod Kumar ◽  
Omkar Kaur ◽  
...  

Malignant melanoma of the rectum is an extremely rare disease. It typically presents in the fifth or sixth decade of life with nonspecific complaints such as rectal bleeding or anal pain. A timely diagnosis of anal melanoma is made even more difficult by the fact that most of the lesions lack obvious pigmentation and are even histologically amelanotic. Prognosis is very poor. Anorectal malignant melanomas spread along submucosal planes and are often beyond complete resection at the time of diagnosis. We present the radiological and pathological features seen in a 43-year-old woman diagnosed with melanoma of the rectum.


2020 ◽  
pp. 1-6
Author(s):  
Hidetsugu Mori ◽  
Kanji Takahashi

A 78-year-old female experienced extraocular extension of a giant conjunctival melanocytic mass. The clinical diagnosis was conjunctival malignant melanoma. We performed local excision and histopathological examination. The result of hematoxylin-eosin staining disclosed multiple intralesional mucosal cysts and nevus cell nests with abundant melanin. Immunohistochemical examination revealed expression of S-100, melan-A, and HMB-45 and no expression of Ki-67. Histopathological examination showed no evidence of malignancy. Giant conjunctival melanocytic nevi can be diagnostically confused with conjunctival malignant melanoma.


Author(s):  
Bushra Siddiqui ◽  
Shahbaz Habib Faridi ◽  
Syed Shamshad Ahmad ◽  
Kafil Akhtar ◽  
Suhailur Rehman ◽  
...  

2021 ◽  
pp. 137-141
Author(s):  
Ayaka Takasu ◽  
Takashi Ikeya ◽  
Katsuyuki Fukuda

The incidence of press-through pack (PTP) ingestion has been increasing. In many cases, the ingested PTP is lodged in the esophagus. Here, we report a case of endoscopic removal of a PTP from the anal canal. An 89-year-old man with mild dementia presented with a 3-day history of anal pain. On digital rectal examination, we felt a hard and sharp object, which could not be manually removed due to its shape. Therefore, it was removed endoscopically. We inserted an endoscope with a large-caliber soft oblique cap and observed the PTP in the anal canal. It was successfully removed using grasping forceps. The patient was stable, with only mild anal fissures, and no serious complications such as perforation and bleeding were observed. It is generally recognized that a PTP that reaches the large intestine is naturally expelled. Even if a PTP could pass through the pylorus or the small intestine, it could still be difficult to discharge naturally from the anus without discomfort or pain, as in this case.


2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Shahzad Ahmad ◽  
Mahmoud Abdelghany ◽  
Curtis Goldblatt ◽  
Owen Stark ◽  
Nicholas Masciotra

Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures.


2021 ◽  
Vol 14 (4) ◽  
pp. e240621
Author(s):  
Swanit Hemant Deshpande ◽  
Vishal Narkhede ◽  
Sai Krishna Eswaravaka ◽  
Jayashri Sanjay Pandya

Malignant melanoma of the anal canal is a rare and aggressive tumour associated with significant mortality. Early diagnosis and early curative surgical resection have shown to offer a survival advantage. We present a case of 53-year-old woman, who was accidentally diagnosed to have a localised lesion of malignant melanoma of the anal canal on histopathology report of the specimen of haemorrhoidectomy done for thrombosed external haemorrhoids. She refused any form of treatment and did not return for follow-up. Two years after the initial diagnosis, she presented with intestinal obstruction. The malignant melanoma had become advanced with multiple metastases to the lungs, the liver, the peritoneum and the spine. The patient underwent a diverting loop ileostomy. At the time of surgery, it was found that the primary malignant melanoma of anal canal had contiguously involved the entire large intestine up to the ileocaecal junction and hence transverse colostomy could not be done.


2018 ◽  
Vol 9 (2) ◽  
pp. 78-82
Author(s):  
Krishna Pada Saha ◽  
Md Ibnul Hasan ◽  
Fayem Chowdhury ◽  
Abdullah Md Abu Ayub Ansary ◽  
Sadia Imdad ◽  
...  

Objective: The aim of the study was to cheek the rate of significant complications amongst the patients undergoing Stapled haemorrhoidectomy. This study reflects our experience with Stapled haemorrhoidectomy in our Population.Methods: Two hundred and ninety patients with primary hemorrhoid of different degree underwent staple Hemorrhoidectomy in ShSMCH since January 2011 to December 2016. All patients were evaluated by history, clinical examination and proctosigmoidoscopy. They were followed up post operatively at 1, 3, 6, 12, 15, 18 Month.Result : Regarding presenting symptoms (pain less) per rectal bleeding was the main symptom (89%). Bulk of the pt were 3rd degree(50.16%). Regarding post operative complication – Urgency of defecation was most frequent (19%). Others were Urinary retention (4.5%), anal pain (4.01%), reactionary hemorrhage (4.01%). Regarding late post operative complication most frequent was mild pain (3.34%); others were – flatus incontinence, stenosis, recurrent haemorrhoid, fissure.Conclusion : Stapled haemorrhaidectomy is widely used, quick, safe and effective method of treating all degree of primary hemorrhoid with some complications. Therefore surgeon should be well aware of the type and post operative complicationsJ Shaheed Suhrawardy Med Coll, December 2017, Vol.9(2); 78-82


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