Malignant Melanoma of Anal Canal – A Diagnostic Dilemma

Author(s):  
Bushra Siddiqui ◽  
Shahbaz Habib Faridi ◽  
Syed Shamshad Ahmad ◽  
Kafil Akhtar ◽  
Suhailur Rehman ◽  
...  
2021 ◽  
Vol 14 (4) ◽  
pp. e240621
Author(s):  
Swanit Hemant Deshpande ◽  
Vishal Narkhede ◽  
Sai Krishna Eswaravaka ◽  
Jayashri Sanjay Pandya

Malignant melanoma of the anal canal is a rare and aggressive tumour associated with significant mortality. Early diagnosis and early curative surgical resection have shown to offer a survival advantage. We present a case of 53-year-old woman, who was accidentally diagnosed to have a localised lesion of malignant melanoma of the anal canal on histopathology report of the specimen of haemorrhoidectomy done for thrombosed external haemorrhoids. She refused any form of treatment and did not return for follow-up. Two years after the initial diagnosis, she presented with intestinal obstruction. The malignant melanoma had become advanced with multiple metastases to the lungs, the liver, the peritoneum and the spine. The patient underwent a diverting loop ileostomy. At the time of surgery, it was found that the primary malignant melanoma of anal canal had contiguously involved the entire large intestine up to the ileocaecal junction and hence transverse colostomy could not be done.


2016 ◽  
Vol 29 ◽  
pp. 20-24 ◽  
Author(s):  
Justin Davis ◽  
Jeevitha Patil ◽  
Nail Aydin ◽  
Aparajita Mishra ◽  
Subhasis Misra

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Gulden Diniz ◽  
Hulya Tosun Yildirim ◽  
Selcen Yamaci ◽  
Nur Olgun

Although rare, malignant melanoma may occur in children. Childhood melanomas account for only 0.3–3% of all melanomas. In particular the presence of congenital melanocytic nevi is associated with an increased risk of development of melanoma. We herein report a case of malignant melanoma that developed on a giant congenital melanocytic nevus and made a metastasis to the subcutaneous tissue of neck in a two-year-old girl. The patient was hospitalized for differential diagnosis and treatment of cervical mass with a suspicion of hematological malignancy, because the malignant transformation of congenital nevus was not noticed before. In this case, we found out a nonpigmented malignant tumor of pleomorphic cells after the microscopic examination of subcutaneous lesion. Nonpigmented metastatic melanoma was diagnosed by several immunohistochemical and flow cytometric studies. She was offered palliative chemotherapy; however, her parents did not accept treatment. The patient died within 9 months of diagnosis. We emphasized here that the possibility of malignant melanoma in the differential diagnosis of childhood tumors should be kept in mind.


2014 ◽  
Vol 29 (3) ◽  
pp. 196 ◽  
Author(s):  
Rakesh Kumar ◽  
ParthaSarathi Chakraborty ◽  
VarunSingh Dhull ◽  
Sellam Karunanithi ◽  
Satyavrat Verma

1970 ◽  
Vol 57 (11) ◽  
pp. 808-811 ◽  
Author(s):  
D. M. Sinclair ◽  
G. Hannah ◽  
I. S. McLaughlin ◽  
R. S. Patrick ◽  
G. Slavin ◽  
...  

1974 ◽  
Vol 7 (6) ◽  
pp. 630-634
Author(s):  
Hiroyuki YOSHIDA ◽  
Shozo BABA

2021 ◽  
Vol 5 (1) ◽  
pp. 57-59
Author(s):  
Ishan Dhungana ◽  
Ranjan Raj Bhatta ◽  
Greta Pandey ◽  
Suraj Upreti ◽  
Nadita Shah ◽  
...  

Anal melanoma (AM) is a rare and highly aggressive mucosal melanocytic malignancy. We report a case of 70 year old male presented with chief complaints of anal pain and intermittent rectal bleeding with clinical diagnosis of Polyp or Carcinoma. On histopathology examination malignant melanoma was suggested which was further confirmed by immunohistochemistry (S100 and HMB 45 strongly positive). Anal melanoma is rare neoplastic condition with catastrophic outcome.   


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