scholarly journals Assessment of Cardiovascular Autonomic Functions to Predict Development of Pregnancy Induced Hypertension

1970 ◽  
Vol 6 (1) ◽  
pp. 41-45
Author(s):  
Nandini Kapoor ◽  
Rajeev Sharma ◽  
Munish Ashat ◽  
Anju Huria ◽  
Ghansham Mishra
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Early Stage ◽  
Blood Pressure Response ◽  
Isometric Exercise ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Roc Curve Analysis ◽  
Pressor Test ◽  
Dynamometer Test

Aim: This study aimed at performing autonomic function tests to predict PIH at early stage of pregnancy. Methods: 200 pregnant women between 12 to 20 weeks of gestation were selected for study. Handgrip dynamometer test (HGT) and Cold pressor test (CPT) were performed to assess sympathetic cardiovascular functions. Result: It was observed that 31 women out of 200 pregnant women developed PIH subsequently. ROC curve analysis was done to find out cut off values of high sensitivity and specificity for rise in systolic blood pressure (_SBP) and diastolic blood pressure (_DBP) during CPT and HGT. It was observed that out of 31 women who developed PIH/PE, 87.1% had _SBP _14mm Hg (cut off value) and 83.9% had _DBP _10mm Hg (cut off value) during CPT, both of which were statistically significant (p<0.001). Similarly for HGT, 31 women who developed PIH, _SBP _16 mm Hg and _DBP _14 mm Hg (cut off values) was observed in 96.8% and 83.9% women respectively (p< 0.001). Discriminant analysis showed that the reliability of both the tests in predicting PIH was very high (p<0.001). Conclusion: Thus it can be concluded from the study that heightened blood pressure response to physiological stimuli like cold and isometric exercise early in pregnancy could be used as a suitable tool to predict development of PIH. Key words: Cold pressor test, early detection, Handgrip dynamometer test, PIH DOI: http://dx.doi.org/10.3126/njog.v6i1.5251 NJOG 2011; 6(1): 41-45

Increased blood pressure response to the cold pressor test in pregnant women developing pre-eclampsia

2000 ◽  
Vol 18 (4) ◽  
pp. 399-403 ◽  
Author(s):  
Christian Woisetschläger ◽  
Ulla Waldenhofer ◽  
Andreas Bur ◽  
Harald Herkner ◽  
Herbert Kiss ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Blood Pressure Response ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Pressure Response ◽  
Pressor Test

Variability of the haemodynamic responses to laboratory tests employed in assessment of neural cardiovascular regulation in man

1985 ◽  
Vol 69 (5) ◽  
pp. 533-540 ◽  
Author(s):  
Gianfranco Parati ◽  
Guido Pomidossi ◽  
Agustin Ramirez ◽  
Bruno Cesana ◽  
Giuseppe Mancia
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Test Performance ◽  
Blood Pressure Response ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiovascular Regulation ◽  
Pressor Test ◽  
Carotid Baroreceptor ◽  
Baroreceptor Stimulation

1. In man evaluation of neural cardiovascular regulation makes use of a variety of tests which address the excitatory and reflex inhibitory neural influences that control circulation. Because interpretation of these tests is largely based on the magnitude of the elicited haemodynamic responses, their reproducibility in any given subject is critical. 2. In 39 subjects with continuous blood pressure (intra-arterial catheter) and heart rate monitoring we measured (i) the blood pressure and heart rate rises during hand-grip and cold-pressor test, (ii) the heart rate changes occurring during baroreceptor stimulation and deactivation by injection of phenylephrine and trinitroglycerine, and (iii) the heart rate and blood pressure changes occurring with alteration in carotid baroreceptor activity by a neck chamber. Each test was carefully standardized and performed at 30 min intervals for a total of six times in each subject. 3. The results showed that the responses to any test were clearly different from one another and that this occurred in all subjects studied. For the group as a whole the average response variability (coefficient of variation) ranged from 10.2% for the blood pressure response to carotid baroreceptor stimulation to 44.2% for the heart rate response to cold-pressor test. The variability of the responses was not related to basal blood pressure or heart rate, nor to the temporal sequence of the test performance. 4. Thus tests employed for studying neural cardiovascular control in man produce responses whose reproducibility is limited. This phenomenon may make it more difficult to define the response magnitude typical of each subject, as well as its comparison in different conditions and diseases.

Winter Pattern of Seasonality is Associated With a Blunted Systolic Blood Pressure Response to the Cold Pressor Test

2020 ◽  
Vol 87 (9) ◽  
pp. S352
Author(s):  
Olesia Muravizki ◽  
Faisal Akram ◽  
Melanie Daue ◽  
Kathleen A. Ryan ◽  
Soren Snitker ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Blood Pressure Response ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Pressure Response ◽  
Pressor Test

Abstract P059: Reproducibility of Blood Pressure Response to Cold Pressor Test: the GenSalt Study

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Dongfeng Gu ◽  
Lydia A Bazzano ◽  
Jie Cao ◽  
Jianxin Li ◽  
Jichun Chen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Response ◽  
Cold Pressor Test ◽  
Area Under The Curve ◽  
Cold Pressor ◽  
Original Study ◽  
Pressor Test ◽  
Increased Risk ◽  
The Mean ◽  
Study Participants

Higher blood pressure (BP) response to cold pressor test (CPT) is associated with increased risk of hypertension and cardiovascular diseases. However, it is unknown whether BP response to CPT is a stable and reproducible trait. We repeated the CPT among 568 Han Chinese who participated in the Genetic Epidemiology Network of Salt Sensitivity (GenSalt) four years after the original study. The same CPT protocol was applied in the original and repeated studies. BP was measured prior to and at 0, 1, 2, and 4 minutes after the participants immersed their hand in ice water (3 o C to 5 o C) for 1 minute using a standard mercury sphygmomanometer. On average, study participants were 39.0 years old and 54.0% of them were male. The mean body mass index was 23.6 kg/m 2 , systolic BP was 117.8 mmHg, and diastolic BP was 74.5 mmHg at baseline among study participants. The mean (standard deviation) of systolic BP responses at time 0 and 1 minutes, maximum responses, and area-under-the-curve during CPT were 13.3 (10.1), 4.2 (6.0), 13.6 (9.8) and 10.8 (17.6) mmHg in the original study and 11.1 (9.5), 4.1 (6.0), 11.7 (8.9), and 10.1 (17.1) mmHg in the repeated study. BP responses in the original and repeated studies were highly correlated. For example, the correlation coefficients for systolic BP responses to CPT were 0.4137 at time 0 minute, 0.3711 at time 1 minute, 0.4221 for the maximum responses, and 0.3641 for area-under-the-curve during CPT (all p<0.0001). These data indicate that BP response to CPT is a stable and reproducible trait. Furthermore, BP responses to CPT may be useful for identifying individuals at high risk for hypertension.

scholarly journals Factors Associated With Blood Pressure Response to the Cold Pressor Test: The GenSalt Study

2013 ◽  
Vol 26 (9) ◽  
pp. 1132-1139 ◽  
Author(s):  
M. Zhang ◽  
Q. Zhao ◽  
K. T. Mills ◽  
J. Chen ◽  
J. Li ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Response ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Pressure Response ◽  
Factors Associated ◽  
Pressor Test

scholarly journals Polymorphisms of ACE2 are Associated with Blood Pressure Response to Cold Pressor Test: The GenSalt Study

2012 ◽  
Vol 25 (8) ◽  
pp. 937-942 ◽  
Author(s):  
Jianfeng Huang ◽  
Shufeng Chen ◽  
Xiangfeng Lu ◽  
Qi Zhao ◽  
Dabeeru C. Rao ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Response ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Pressure Response ◽  
Pressor Test
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