Prevalence of Dirofilaria and Hemato-biochemical Effect in Street Dogs of Kathmandu Valley and Siddharthanagar Municipality, Bhairahawa, Nepal

A cross sectional study was conducted to determine the prevalence of dirofilariosis in street dogs of Kathmandu valley and Siddharthanagar, Rupandehi from January 2019 to March 2019. .Blood sample from 155 dogs of Kathmandu Valley and 150 from Siddharthanagar municipality were collected and examined by Wet Smear, Modified Knott Technique and Buffy Coat methods. PCV value and biochemical parameters were analyzed. Data were analyzed to determine the Prevalence of Dirofilaria and correlation of infections with age, sex and biochemical parameters. The prevalence in Kathmandu valley was 0% (0/156) while the prevalence in Siddharthanagar was 19.33%., while the prevalence in direct smear, buffy coat and modified Knott technique were found to be 16%, 16% and 19.33% respectively. The prevalence were significantly (p<0.05) higher in old age and higher in 3-5 years of age i.e. 51.70%..Prevalence was higher in female (21.70%) than male (17.3%).AST and ALT were significantly (p<0.05) increased in infected dogs. Total protein, ALP, BUN, Creatinine level were elevated in the infected dogs.

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Understanding frailty among older people living in old age homes and the community in Nepal: A cross-sectional study

PLoS ONE ◽

10.1371/journal.pone.0251016 ◽

2021 ◽

Vol 16 (4) ◽

pp. e0251016

Author(s):

Richa Shah ◽

Rogie Royce Carandang ◽

Akira Shibanuma ◽

Ken Ing Cherng Ong ◽

Junko Kiriya ◽

...

Keyword(s):

Older People ◽

Old Age ◽

Low Income ◽

Lifestyle Modification ◽

Cross Sectional Study ◽

Living Environment ◽

Kathmandu Valley ◽

Sectional Study ◽

Cross Sectional ◽

Old Age Homes

Introduction Frailty is a state of being vulnerable to adverse health outcomes such as falls, delirium, and disability in older people. Identifying frailty is important in a low-income setting to prevent it from progressing, reducing healthcare costs, increasing the chances of reversibility, and implementing effective interventions. The factors affecting frailty in older people living in old age homes could differ from those living in the community. This study was conducted to identify the factors associated with frailty in older people residing in old age homes and communities in Kathmandu Valley, Nepal. Methods This is a cross-sectional study conducted from April to June 2019 in three districts of Kathmandu Valley, Nepal. Data were collected from 193 older people residing in old age homes and 501 residing in communities aged 60 and above using convenience sampling. Frailty was measured using the Groningen Frailty Indicator. Data were collected via face-to-face interviews. Multiple linear regression analyses were used to examine the association between independent variables and frailty. Results Frailty was more prevalent among older people in old age homes (71.5%) compared to those in the community (56.3%). Older people who were satisfied with their living environment had lower frailty scores in both old age homes (β = -0.20, p<0.01) and the community (β = -0.15, p<0.001). Those who had self-rated unhealthy lifestyle had higher frailty scores in both old age homes (β = 0.45, p<0.001) and the community (β = 0.25, p<0.001). In the community, those over 80 years of age had higher frailty scores (β = 0.15, p<0.01) and those with higher education had lower scores (β = -0.13, p<0.05). Conclusion The living environment and lifestyle are key modifiable risk factors of frailty, both in old age homes and the community. The findings suggest a need for lifestyle modification and reforms in building standards, especially in old age homes, to promote age-friendly communities.

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Comparison of capillary, venous and buffy coat blood samples in detecting Plasmodium species among malaria suspected patients attending at Hamusite health center. A cross-sectional study

BMC Infectious Diseases ◽

10.1186/s12879-021-06290-6 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Getu Abeje ◽

Woyneshet Gelaye ◽

Getaneh Alemu

Keyword(s):

Health Center ◽

Detection Rate ◽

Venous Blood ◽

Cross Sectional Study ◽

Buffy Coat ◽

Blood Film ◽

Capillary Blood ◽

Sectional Study ◽

Cross Sectional ◽

Blood Samples

Abstract Background Both capillary and venous blood samples have been interchangeably used for the diagnosis of malaria in Ethiopia. However, Plasmodium parasites are thought to be more concentrated in capillary than in venous blood. Hence, selecting a sample source where parasites are more concentrated is indispensable approach in order to maximize the accuracy of blood film microscopy. Therefore, the present study aimed to compare the detection rate and the parasitemia level of Plasmodium species from conventional capillary and venous blood films, and buffy coat preparations. Methods A facility based cross-sectional study was conducted from Feburary to March 2020 among 210 febrile patients attending Hamusite health center, northwest Ethiopia. Capillary and venous blood samples were collected and buffy coat was prepared from each sample. Thin and thick blood films were prepared, stained, and examined microscopically following standard protocol. Data were analysed using Statistical Package for Social Sciences Software version 20 and Med-Calc software version 19.3. Results Capillary blood buffy coat (61/210, 29.0%) had significantly higher detection rate as compared to capillary (48/210, 22.9%) and venous (42/210, 20.0%) blood films (p < 0.001). However, no significant difference was observed between capillary and venous blood films (p = 0.070) in detecting Plasmodium species. The highest and the lowest mean asexual stage parasite counts were found in capillary blood buffy coat (4692.88) and venous blood (631.43) films, respectively showing significant variations (p < 0.001). Mean gametocyte count was also highest in capillary blood buffy coat (3958.44). As compared to capillary blood buffy coat, the sensitivity of venous blood buffy coat, capillary blood film and venous blood film were 73.8, 78.7, 68.9%, respectively. Conclusion Capillary blood buffy coat samples showed the highest sensitivity in detecting and quantitating malaria parasites that its use should be promoted in clinical settings. However, conventional capillary and venous blood films could be used interchangeably.

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Effect of Pesticide Exposure on Immunological, Hematological and Biochemical Parameters in Thai Orchid Farmers— A Cross-Sectional Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph120605846 ◽

2015 ◽

Vol 12 (6) ◽

pp. 5846-5861 ◽

Cited By ~ 18

Author(s):

Soraya Aroonvilairat ◽

Wannapa Kespichayawattana ◽

Thiwaree Sornprachum ◽

Papada Chaisuriya ◽

Taweeratana Siwadune ◽

...

Keyword(s):

Biochemical Parameters ◽

Pesticide Exposure ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Hematological And Biochemical Parameters

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Gender differences in cognitive impairment and mobility disability in old age: A cross-sectional study in Ouagadougou, Burkina Faso

Archives of Gerontology and Geriatrics ◽

10.1016/j.archger.2013.06.007 ◽

2013 ◽

Vol 57 (3) ◽

pp. 311-318 ◽

Cited By ~ 21

Author(s):

Yentéma Onadja ◽

Nicole Atchessi ◽

Bassiahi Abdramane Soura ◽

Clémentine Rossier ◽

Maria-Victoria Zunzunegui

Keyword(s):

Gender Differences ◽

Cognitive Impairment ◽

Burkina Faso ◽

Old Age ◽

Cross Sectional Study ◽

Sectional Study ◽

Mobility Disability ◽

Cross Sectional

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Changing the quality of life in old age bariatric patients. Cross-sectional study for 79 old age patients

International Journal of Surgery ◽

10.1016/j.ijsu.2018.04.050 ◽

2018 ◽

Vol 54 ◽

pp. 236-241 ◽

Cited By ~ 1

Author(s):

Elie Chouillard ◽

Salman Alsabah ◽

Elias Chahine ◽

Elias Saikaly ◽

Tarek Debs ◽

...

Keyword(s):

Quality Of Life ◽

Old Age ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Bariatric Patients

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Neopterin and Biochemical Parameters as Indicators of Predicting HIV Disease Progression and Treatment Response: A Cross-sectional Study in Ghana

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2019/v29i330075 ◽

2019 ◽

pp. 1-10

Author(s):

Louis Boafo Kwantwi ◽

Christian Obirikorang ◽

Margaret Agyei Frempong ◽

Dan Yedu Quansah

Keyword(s):

Disease Progression ◽

Highly Active Antiretroviral Therapy ◽

Biochemical Parameters ◽

Cross Sectional Study ◽

Hiv Disease ◽

Sectional Study ◽

Cross Sectional ◽

Highly Active ◽

Hiv Seropositive ◽

Therapy Treatment

Background: Surrogate markers have been identified to play significant role in the pathogenesis and prognosis of HIV infection. However, there is limited data on the utility of neopterin estimation in HIV infection. Therefore, the study sought to measure and ascertains the trends of serum neopterin and other biochemical parameters as indicators of predicting HIV disease progression and treatment response among HIV seropositive individuals. Methods: A cross-sectional study with 298 HIV seropositive individuals consisting of 165 HIV on highly active antiretroviral treatment and 136 naïve highly active antiretroviral patients. Venous blood was drawn for the assay of neopterin and the other biochemical parameters. Results: Neopterin was significantly lower (P<0.0001) in patients in the highly active antiretroviral therapy than those in the naïve highly active antiretroviral therapy group. Serum neopterin increased as the disease progresses and decreased as the duration of the therapy treatment increased (p=0.0001). At a cut of point of 54.5 nmol/L, neopterin gave a sensitivity of 97.5%, specificity of 95.9% and an area under the curve of 0.99. Conclusion: Neopterin has shown to be to be good marker in predicting HIV disease progression especially in patients with CD4 counts less than 200mm-3 and a useful indicator of patient’s response to therapy treatment.

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