Downy mildew (DM) is a serious foliar fungal disease of cucurbits. DM can cause yield losses for New Jersey growers if not properly controlled. In 2004, five chemical control programs were evaluated in a research trial at the Rutgers Snyder Research and Extension Farm (Hunterdon Co.). Materials evaluated were: 1) Phostrol, 5 pt/A; 2) Phostrol, 5 pt/A plus Bravo WS, 3 pt/A; 3) Flint WDG, 2 oz/A alternated with Bravo WS, 3 pt/A plus Nova 40W, 5 oz/A; 4) Maneb 75DF, 2 lb/A plus Champ Formula 2 Flowable, 1 1/3 pt/A; and 5) untreated control. All fungicide programs were applied weekly. Phostrol (Nufarm Americas, Inc.) is a new product with systemic mode of action that is newly labeled for cucurbits for control of DM, but not powdery mildew (PM). The active ingredients are mono- and dibasic-sodium, potassium, and ammonium phosphates. Phostrol and Phostrol plus Bravo were evaluated against industry standard fungicide programs which include alternating chlorothalonil + myclobutanil with strobiluron chemistries on a weekly basis. Fungicide applications were made weekly beginning at first observance of DM in the field on 23 July. Plots were rated for DM and PM incidence and extent of defoliation on 6 Aug. and 24 Sept. Phostrol plus Bravo applied on a weekly basis (7 to 10 days) provided the best control of DM, which appeared much earlier in the season than usual in northern New Jersey. Treatments Phostrol, Flint alternated with Bravo + Nova, Maneb + Champ reduced DM compared to the UTC. Maneb plus Champ provided the best control for PM. At harvest, fruit was graded and weighed. Marketable yield from Phostrol, Phostrol plus Bravo and Maneb plus Champ treatments was significantly higher than the UTC and Flint/Bravo plus Nova treatment. Handle quality was not affected by treatment.