scholarly journals DIAGNOSIS OF THE FUNCTIONAL STATE OF AUTONOMIC REGULATION AND PROGNOSIS OF MALADAPTATION DEVELOPMENT

2021 ◽  
Author(s):  
Dmytro Igorovych Marakushyn ◽  
◽  
Larysa Volodymyrivna Chernobay ◽  
Inna Mykolayivna Isaieva ◽  
Iryna Stanislavivna Karmazina ◽  
...  

It was demonstrated that medical students with vagotonia and sympathicotonia had a mild strain of their regulation mechanisms. The considerable signs of autonomic regulation inefficiency were found out in conditions of physical exercising. The adaptation of individuals with vagotonia to the physical loading was going mainly due to the excessive elevation of heart rate along with the increase in diastolic blood pressure. In contrast, abnormal elevation of pulse pressure after physical loading was observed in young people with sympathicotonia, which is concerned as a negative prognosis and also a predictor of arterial hypertension. Some physiological aspects of the recovery period confirmed the insufficiency of autonomic regulation as well as discoordination of the reciprocal departments of autonomic nervous system in examined persons. The unfavorable range of increase in hemodynamic parameters after physical loading was to pioneer. The following ranges of cardiovascular indexes indicated the mild level of maladaptation: in individuals with vagotonia – Mean Arterial Pressure by 6-30%, heart rate by 80-120%, endurance coefficient – 5-27%, and Robinson’s index – 121–200%; in persons with sympathicotonia – endurance coefficient – 5-27%, and Pulse Pressure – 75-105%. These changes have to be corrected in advance for the prophylactics of specific and nonspecific complications of visceral systems functioning. The economical effectiveness of this research is accomplished by the reduction of financial expenses because of prophylactics and/or diagnosis of autonomic deregulation development

2021 ◽  
pp. 1-7
Author(s):  
Tércio A.R. Barros ◽  
Wagner L. do Prado ◽  
Thiago R.S. Tenório ◽  
Raphael M. Ritti-Dias ◽  
Antônio H. Germano-Soares ◽  
...  

This study compared the effects of self-selected exercise intensity (SEI) versus predetermined exercise intensity (PEI) on blood pressure (BP) and arterial stiffness in adolescents with obesity. A total of 37 adolescents, 14.7 (1.6) years old, body mass index ≥95th percentile were randomly allocated into SEI (n = 18; 12 boys) or PEI (n = 19; 13 boys). Both groups exercised for 35 minutes on a treadmill, 3 times per week, for 12 weeks. The SEI could set the speed at the beginning of the sessions and make changes every 5 minutes. The PEI adolescents were trained at an intensity set at 60% to 70% of heart rate reserve. Brachial and central BP, pulse pressure, augmentation index, and carotid–femoral pulse wave were determined at baseline and after 12 weeks. Both groups reduced brachial systolic BP (SEI, Δ = −9 mm Hg; PEI, Δ = −4 mm Hg; P < .01), central systolic BP (SEI, Δ = −4 mm Hg; PEI, Δ = −4 mm Hg; P = .01), and central pulse pressure (SEI, Δ = −4 mm Hg; PEI, Δ = −3 mm Hg; P = .02) without differences between groups. No changes in the augmentation index and carotid–femoral pulse wave were observed in either group. The SEI induced similar changes in various cardiovascular outcomes compared with PEI in adolescents with obesity.


Entropy ◽  
2018 ◽  
Vol 20 (11) ◽  
pp. 860 ◽  
Author(s):  
Marcos Hortelano ◽  
Richard Reilly ◽  
Francisco Castells ◽  
Raquel Cervigón

Orthostatic intolerance syndrome occurs when the autonomic nervous system is incapacitated and fails to respond to the demands associated with the upright position. Assessing this syndrome among the elderly population is important in order to prevent falls. However, this problem is still challenging. The goal of this work was to determine the relationship between orthostatic intolerance (OI) and the cardiovascular response to exercise from the analysis of heart rate and blood pressure. More specifically, the behavior of these cardiovascular variables was evaluated in terms of refined composite multiscale fuzzy entropy (RCMFE), measured at different scales. The dataset was composed by 65 older subjects, 44.6% (n = 29) were OI symptomatic and 55.4% (n = 36) were not. Insignificant differences were found in age and gender between symptomatic and asymptomatic OI participants. When heart rate was evaluated, higher differences between groups were observed during the recovery period immediately after exercise. With respect to the blood pressure and other hemodynamic parameters, most significant results were obtained in the post-exercise stage. In any case, the symptomatic OI group exhibited higher irregularity in the measured parameters, as higher RCMFE levels in all time scales were obtained. This information could be very helpful for a better understanding of cardiovascular instability, as well as to recognize risk factors for falls and impairment of functional status.


2020 ◽  
Vol 30 (6) ◽  
pp. 531-540
Author(s):  
Hendrik Kronsbein ◽  
Darius A. Gerlach ◽  
Karsten Heusser ◽  
Alex Hoff ◽  
Fabian Hoffmann ◽  
...  

Abstract Introduction Baroreflexes and peripheral chemoreflexes control efferent autonomic activity making these reflexes treatment targets for arterial hypertension. The literature on their interaction is controversial, with suggestions that their individual and collective influence on blood pressure and heart rate regulation is variable. Therefore, we applied a study design that allows the elucidation of individual baroreflex–chemoreflex interactions. Methods We studied nine healthy young men who breathed either normal air (normoxia) or an air–nitrogen–carbon dioxide mixture with decreased oxygen content (hypoxia) for 90 min, with randomization to condition, followed by a 30-min recovery period and then exposure to the other condition for 90 min. Multiple intravenous phenylephrine bolus doses were applied per condition to determine phenylephrine pressor sensitivity as an estimate of baroreflex blood pressure buffering and cardiovagal baroreflex sensitivity (BRS). Results Hypoxia reduced arterial oxygen saturation from 98.1 ± 0.4 to 81.0 ± 0.4% (p < 0.001), raised heart rate from 62.9 ± 2.1 to 76.0 ± 3.6 bpm (p < 0.001), but did not change systolic blood pressure (p = 0.182). Of the nine subjects, six had significantly lower BRS in hypoxia (p < 0.05), two showed a significantly decreased pressor response, and three showed a significantly increased pressor response to phenylephrine in hypoxia, likely through reduced baroreflex buffering (p < 0.05). On average, hypoxia decreased BRS by 6.4 ± 0.9 ms/mmHg (19.9 ± 2.0 vs. 14.12 ± 1.6 ms/mmHg; p < 0.001) but did not change the phenylephrine pressor response (p = 0.878). Conclusion We applied an approach to assess individual baroreflex–chemoreflex interactions in human subjects. A subgroup exhibited significant impairments in baroreflex blood pressure buffering and BRS with peripheral chemoreflex activation. The methodology may have utility in elucidating individual pathophysiology and in targeting treatments modulating baroreflex or chemoreflex function.


Global Heart ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e130
Author(s):  
Bertrand F. Ellenga Mbolla ◽  
Thierry R. Gombet ◽  
Annie R. Okoko ◽  
Christian M. Koula Landa ◽  
suzy-Gisèle Kimbally-Kaky ◽  
...  

1974 ◽  
Vol 47 (3) ◽  
pp. 249-257 ◽  
Author(s):  
D. F. Marcus ◽  
H. F. Edelhauser ◽  
M. G. Maksud ◽  
R. L. Wiley

1. Normal subjects performed fatiguing static hand-grip contraction at tensions of 20% and 55% of their maximum voluntary contraction (MVC). Intraocular pressure (IOP) was measured by applanation tonometry before, during and after the isometric exercise. Forearm blood samples were taken from the antecubital vein in both the exercised and non-exercised arm before and 2 min post-exercise for measurement of plasma lactate, osmolality, Pv,o2, Pv,co2 and pH. 2. During hand grip the heart rate and blood pressure increased significantly, whereas the IOP remained unchanged from control in both the 20% and 55% MVC experiments. 3. In the recovery period heart rate and blood pressure returned to control values within 3 min and the IOP decreased significantly from control in both the 20% and 55% MVC experiments. 4. When an occlusion cuff was inflated on the exercising arm just before release of the 55% MVC grip, the decreased IOP could be delayed until the cuff was released. 5. Post-exercise blood samples showed elevated lactate concentrations and Pv,o2 and decreased pH in the exercised arm; however, the values remained unchanged in the non-exercised arm. The decreased IOP after exercise may be related to an increased blood lactate concentration.


Author(s):  
Diego Giulliano Destro Christofaro ◽  
Juliano Casonatto ◽  
Luiz Carlos Marques Vanderlei ◽  
Gabriel Grizzo Cucato ◽  
Raphael Mendes Ritti Dias

1996 ◽  
Vol 91 (s1) ◽  
pp. 129-132 ◽  
Author(s):  
Gianfranco Parati ◽  
Alessandra Frattola ◽  
Stefano Omboni ◽  
Giuseppe Mancia ◽  
Marco Di Rienzo

2020 ◽  
Vol 24 (4) ◽  
pp. 195-202
Author(s):  
Javad Mehrabani ◽  
Soodabeh Bagherzadeh ◽  
Abuzar Jorbonian ◽  
Eisa Khaleghi-Mamaghani ◽  
Maryam Taghdiri ◽  
...  

Background and Study Aim. During exercise, the effects of music on the performance have been previously evaluated. However, the superiority of the type of music and during recovery is not yet clear. Therefore the aim of this study was to determine the impact of music with a spicy and light beat on changes in lactate levels, blood pressure, heart rate, and appetite during the recovery period after the endurance swimming. Material and Methods. Thirteen healthy young girls participate in three control and experimental sessions. The participants performed a swimming. Immediately after swimming, they listened to music. Also, evaluations before and after (several times) swimming were performed.Results. Five minutes after swimming there was also a significant difference between the non-sound group with the music groups (p<0.05). Two and 5 minutes after swimming, there was a significant difference between the spicy and light music groups compared to the non-sound group. There was a significant difference between spicy and light music groups at time 10, 15 and 25 minutes. In the 25 minutes after the swim, reducing the heart rate in light music was more than spicy. Also, 10 minutes after swimming, the spicy music group could not cope with the increase in heart rate (p<0.05). There was a significant difference between the two music groups in minutes 5, 10 and 15 after swimming (p<0.05).Conclusions. listening to light music during recovery from endurance swimming was associated with decreased lactate levels and heart rate, but listening to spicy music increased heart rate and desire for food.


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