scholarly journals Assessment of medication adherence and quality of life among patients with type 2 diabetes mellitus in a tertiary hospital in Kelantan, Malaysia

2021 ◽  
Vol 1 (2) ◽  
pp. 79-86
Author(s):  
Nazmi Liana Azmi ◽  
Nurul Aida Md Rosly ◽  
Hock Chun Tang ◽  
Anis Fariha Che Darof ◽  
Nor Dini Zuki

Introduction: Previous studies have reported the relationship between medication adherence and quality of life are interrelated. However, many of the results were found to be conflicting. This study aimed to assess the level and association of medication adherence and quality of life among type 2 diabetes mellitus patients in Raja Perempuan Zainab II Hospital, Kelantan, Malaysia. Materials and methods: A cross-sectional survey was conducted among adult type 2 diabetes mellitus patients on treatment for over 1 year using convenience sampling at outpatient.  Medication Compliance Questionnaire (MCQ) and revised Diabetes Quality of Life Questionnaire (DQOL) instrument were self-administered to eligible subjects. Data were analysed using GNU PSPP version 0.8.5 and reported for descriptive statistics as well as correlation of both parameters. Results: A total of 200 patients were recruited and they were mostly at the age of 40 to 60 years old. The mean (SD) score for MCQ was 26.0 (1.6) with the majority of them were non-adherent (55.0%, n=110). The mean (SD) score for overall revised DQOL instrument was 25.5 (8.9) while each domain of “satisfaction”, “impact” and “worry” had mean (SD) scores of 12.0 (5.0), 7.7 (3.4) and 5.9 (2.7), respectively. The scores obtained were only approximately half of the possible range of scores for QoL. There was no significant correlation between total score of medication adherence and quality of life when tested using Pearson’s correlation (r=-0.083, p=0.240). Independent t-test also demonstrated no significant relationship between medication adherence status and quality of life (p=0.883). Conclusion: Type 2 diabetes mellitus patients in our setting had unsatisfactory adherence but exhibited acceptable quality of life. We observed that both variables were not associated with one another. Further research is warranted to identify potential factors affecting non-adherence to medication.

Author(s):  
Hardesh Dhillon ◽  
Rusli Bin Nordin ◽  
Amutha Ramadas

Diabetes complications, medication adherence, and psychosocial well-being have been associated with quality of life (QOL) among several Western and Asian populations with diabetes, however, there is little evidence substantiating these relationships among Malaysia’s unique and diverse population. Therefore, a cross-sectional study was conducted in a Malaysian public primary care clinic among 150 patients diagnosed with type 2 diabetes mellitus (T2DM). Structured and validated questionnaires were used to investigate the associations between demographic, clinical, and psychological factors with QOL of the study participants. Approximately three-quarters of patients had a good-excellent QOL. Diabetes-related variables that were significantly associated with poor QOL scores included insulin containing treatment regimens, poor glycemic control, inactive lifestyle, retinopathy, neuropathy, abnormal psychosocial well-being, higher diabetes complication severity, and nonadherence (p < 0.05). The main predictors of a good-excellent QOL were HbA1c ≤ 6.5% (aOR = 20.78, 95% CI = 2.5175.9, p = 0.005), normal anxiety levels (aOR = 5.73, 95% CI = 1.8–18.5, p = 0.004), medication adherence (aOR = 3.35, 95% CI = 1.3–8.7, p = 0.012), and an aDCSI score of one and two as compared to those greater than or equal to four (aOR = 7.78, 95% CI = 1.5–39.2, p = 0.013 and aOR = 8.23, 95% CI = 2.1–32.8, p = 0.003), respectively. Medication adherence has also been found to be an effect modifier of relationships between HbA1c, depression, anxiety, disease severity, and QOL. These predictors of QOL are important factors to consider when managing patients with T2DM.


2019 ◽  
Vol 7 (8) ◽  
pp. 1401-1405 ◽  
Author(s):  
Shofian Syarifuddin ◽  
Azizah Nasution ◽  
Aminah Dalimunthe ◽  
Khairunnisa

AIM: To analyse the characteristics, and analyse the impact of pharmacist intervention on quality of life (QOL) outpatients with type 2 diabetes mellitus (T2DM). METHODS: This six-month analytical cohort study was conducted by assessing the patients’ characteristics and their quality of life by distributing a questionnaire, and the 36-Item short form instrument to the patients with T2DM (n = 45) admitted to the Tertiary hospital in Tebing Tinggi. Patients who had mental disorders, HIV-AIDS, liver disease, stage 4 chronic kidney disease, and pregnant women were excluded from the study. The patients’ quality of life was measured before and after interventions and analysed using the paired t-test. All analyses were performed using the Statistical Package for the Social Sciences (SPSS, version 22, Chicago, IL, USA) (p < 0.05 was considered significant). RESULTS: The mean age of the patients was 61.96 ± 6.45 (years). Most (66.7%) of them were females. The mean QOL (in the score) of the patients: before the intervention, 61.07 ± 15.13; after the intervention, 70.15 ± 14.23, there was a significant difference between groups with and without interventions, p < 0.001. CONCLUSION: Active contribution of pharmacists in the management of T2DM patients is urgent and important to improve the patients’ QOL.


2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Kosana Stanetić ◽  
Maja Račić ◽  
Vesna Kević

Introduction.The aim of the study was to find out the determinants of thequality of life in primary health care patients with type 2 diabetes.Methods. The cross-sectional study included 181 patients, aged 37 to 89 years,with diabetes mellitus type 2, registered with four family medicine practices.The assessment of health status was conducted using medical history, objectiveexamination, laboratory analyses, dilated eye exam, screening for distalsymmetric neuropathy and ankle-brachial index measurement. In evaluatingthe impact of diabetes mellitus on patients’ health status, a generic instrument,the self-administered WHOQOL-BREF questionnaire, was used. Multivariatelinear regression models were used to analyze the variables associated withthe quality of life.Results. Out of 181 adult patients with type 2 diabetes mellitus, 73 (40.3%)had diabetes for less than 5 years. The mean glycated hemoglobin (A1C) was7.55% and the mean serum levels of fasting glucose, total cholesterol, LDL-cholesterol,HDL-cholesterol and triglycerides were above the recommendedvalues. Most of the patients had comorbidities, chronic diabetes complicationsand used oral hypoglycemic agents in combination with insulin. Themultivariate regression analysis showed that the age, psychological health,nephropathy and environment were associated with the domain of physicalhealth. The determinants of psychological health were age, marital statusand environment. Older and single patients had lower scores, whereas thosewith a better living environment had higher scores in the domain of socialrelationship. The levels of glycemic control and gender have not been shownto be significant determinants of any of the four domains.Conclusion. The factors associated with the different domains of quality oflife in patients with type 2 diabetes are multiple, but mainly relate to age,living environment and diabetes complications. The results can be used as aguideline for defining measures that can improve the quality of life of patientswith type 2 diabetes


2017 ◽  
Vol 4 (2) ◽  
pp. 125-133
Author(s):  
Erni Setiyorini ◽  
Ning Arti

Abstract. Type 2 Diabetes Mellitus is mostly elderly. In the aging process, glucose tolerance decreases. The most common problem occurs in patients with DM is to maintain ideal body weight. Some elderly people have problems with excessive weight and some malnutrition. The condition of malnutrition in elderly with type 2 diabetes has an effect on physical and psychological function, both of these factors are important in the satisfaction of quality of life. The quality of life of DM patients is a feeling of satisfaction and happiness will live in general, especially with diabetes mellitus. The aims of this study was to determine the relationship between nutritional status and functional capacity with the quality of life of elderly people with diabetes mellitus type 2. The design in this study is correlational with cross sectional approach. Sampling technique of accidental sampling. Identify elderly people with type 2 diabetes in accordance with the inclusion criteria, then Data collection is done by weighing weight and measuring the height of elderly, filling the quality of life questionnaire, and functional capacity. Data analysis using Spearman Rank. The results showed that there was a significant relationship between nutritional status and functional capacity with quality of life of elderly people with type 2 diabetes, the correlation of each with r = 0,000 and r = 0.003. Expected For health workers to provide motivation to patients to maintain a good lifestyle so as to minimize complications and quality of life of the elderly either. For families to support and facilitate healthy lifestyles in elderly people with type 2 diabetes to achieve the most nutritional status and functional status according to age and ability. Keywords: elderly people with type 2 DM, functional capacity, nutritional status, quality of life.


2021 ◽  
Vol 12 (10) ◽  
pp. 1740-1749
Author(s):  
Rakhi Mishra ◽  
Suresh K Sharma ◽  
Rajni Verma ◽  
Priyanka Kangra ◽  
Preeti Dahiya ◽  
...  

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