scholarly journals Prevalence and Outcome of Advanced Left Ventricular Diastolic Dysfunction among Consecutive Patients Referred for Echocardiography

2021 ◽  
pp. 1-6
Author(s):  
Mady Moriel ◽  
Mady Moriel ◽  
Adi Butnaru ◽  
Marc Klutstein ◽  
Rivka Farkash ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Systolic Function ◽  
The Elderly ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Mortality Data ◽  
Hypertensive Patients ◽  
All Cause Mortality ◽  
Ventricular Diastolic Dysfunction ◽  
Grade Ii

Aim: To assess the prevalence of advanced left ventricular diastolic dysfunction (LVDD) in a cohort of consecutive patients referred for echocardiography and its association with mortality. Methods: The cohort included 4,481 (85% hospitalized) patients who underwent echocardiography, had normal or preserved LV systolic function and diastolic function assessment. LVDD was graded as none or mild (0/I) and advanced grade (II/III). Mortality data were derived from the National Israeli Population Registry. Results: LVDD grade II/III was found in 1,262 patients (28%), was more prevalent among the elderly, females, diabetic and hypertensive patients. Independent predictors associated with LVDD grade II/III (OR; 95% CI) were: age (1-year increment) 1.015 (1.01-1.02), p<0.001; female sex 1.2 (1.04-1.39), p=0.012; hypertension 1.53 (1.30-1.80), p<0.001, while ischaemic heart disease was negatively associated 0.73 (0.63- 0.85), p<0.001. 1-year mortality rates were higher among grade II/III LVDD as compared to grade 0/I DD patients, 19% vs. 10.2%, respectively, p<0.0001. Independent predictors for all-cause mortality after adjusting for pertinent variables were: LVDD grade II/III 1.72 (1.40-2.11); age (1-year increment) 1.08 (1.07-1.09) and diabetes 1.54 (1.26-1.70), p<0.001 for all. Conclusion: LVDD grade II/III was more prevalent among the elderly, females, diabetic and hypertensive patients. Advanced LVDD was a strong independent predictor for all-cause mortality after adjustment for risk factors. Intensive pharmacological therapies at an earlier stage of LVDD may improve patients’ outcome.

Left Ventricular Diastolic Dysfunction Is Related to Oxidative Stress and Exercise Capacity in Hypertensive Patients with Preserved Systolic Function

Cardiology ◽  
2006 ◽  
Vol 108 (1) ◽  
pp. 62-70 ◽  
Author(s):  
Milica Dekleva ◽  
Vera Celic ◽  
Nada Kostic ◽  
Biljana Pencic ◽  
Ana M. Ivanovic ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diastolic Dysfunction ◽  
Exercise Capacity ◽  
Systolic Function ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Ventricular Diastolic Dysfunction

Prevalence and renal prognosis of left ventricular diastolic dysfunction in non-dialysis chronic kidney disease patients with preserved systolic function

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Silvio Borrelli ◽  
Luca De Nicola ◽  
Carlo Garofalo ◽  
Ernesto Paoletti ◽  
Sergio Lucà ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Diastolic Dysfunction ◽  
Systolic Function ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ventricular Diastolic Dysfunction ◽  
Renal Prognosis

scholarly journals SP576IMPACT OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION FOR PREDICTING CARDIOVASCULAR EVENTS IN HEMODIALYSIS PATIENTS WITH PRESERVED SYSTOLIC FUNCTION

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii328-iii328
Author(s):  
Tatsunori Toida ◽  
Reiko Toida ◽  
Norihiko Koyama ◽  
Shigehiro Uezono ◽  
Hiroyuki Komatsu ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Cardiovascular Events ◽  
Systolic Function ◽  
Hemodialysis Patients ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ventricular Diastolic Dysfunction

Left Ventricular Diastolic Dysfunction in South Indian Essential Hypertensive Patients

2015 ◽  
Vol 3 (1) ◽  
pp. 76
Author(s):  
Peersab M Pinjar ◽  
Praveenkumar Devarbahvi ◽  
C R Vasudeva Murthy ◽  
S S Bhat ◽  
S G Jayaraj
Keyword(s):  
Diastolic Dysfunction ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
South Indian ◽  
Ventricular Diastolic Dysfunction

scholarly journals 8 A Scoring System for Detecting Left Ventricular Diastolic Dysfunction in Hypertensive Patients

2017 ◽  
Vol 35 ◽  
pp. e1-e2
Author(s):  
Donny Setyawan Syamsul ◽  
Nani Hersunarti ◽  
Lies Dina Liastuti ◽  
Aria Kekalih ◽  
Rarsari Soerarso ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Scoring System ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Ventricular Diastolic Dysfunction

scholarly journals Grading of Left Ventricular Diastolic Dysfunction with Preserved Systolic Function by the 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging Recommendations Contributes to Predicting Cardiovascular Events in Hemodialysis Patients

2019 ◽  
Vol 9 (3) ◽  
pp. 190-200 ◽  
Author(s):  
Tatsunori Toida ◽  
Reiko Toida ◽  
Risa Yamashita ◽  
Norihiro Komiya ◽  
Shigehiro Uezono ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Cardiovascular Events ◽  
Systolic Function ◽  
Hemodialysis Patients ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Kaplan Meier ◽  
Ventricular Diastolic Dysfunction ◽  
Cox's Regression ◽  
American Society

Background: Left ventricular diastolic dysfunction (LVDD) causes heart failure with a preserved left ventricular ejection fraction (LVEF) in the general population. Objective: To examine the relationships between the LVDD grades of the 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging (ASE/EACVI) recommendations and several arteriosclerotic parameters and major cardiovascular events (MACE) in hemodialysis patients with preserved LVEF. Method: Sixty-three prevalent hemodialysis patients (median age [interquartile range], 69 [64–75] years, 31.7% female) with normal systolic function (LVEF > 50%) were enrolled. LVDD evaluated by echocardiography at baseline was divided into three groups according to ASE/EACVI recommendations (normal diastolic function [ND], n = 24; intermediate, n = 19; diastolic dysfunction [DD], n = 20). All patients underwent analyses of several arteriosclerotic parameters (carotid intima-media thickness [CIMT], plaque score [PS], ankle brachial index [ABI], and brachial-ankle pulse wave velocity [baPWV]). The presence or absence of postdialysis orthostatic hypotension was assessed in each dialysis session. MACE during the 1-year follow-up period was obtained from medical records. Kaplan-Meier and Cox’s regression analyses were used to investigate the relationship between LVDD grades and MACE. Results: Postdialysis orthostatic hypotension and PS, but not CIMT, ABI, or baPWV, increased proportionally with LVDD grades. Eleven patients developed MACE, including 2 cardiovascular deaths. The Kaplan-Meier analysis showed that MACE frequently occurred in the DD grade (p = 0.002 by the log-rank test). Cox’s regression analysis adjusted for potential confounders (age, sex, diabetes, systolic blood pressure, and body mass index) revealed that the DD grade was associated with MACE when the ND grade was set as a reference. Conclusions: In maintenance hemodialysis patients with normal ventricular systolic function, a classification of LVDD by the 2016 ASE/EACVI recommendations may be a useful tool for predicting cardiovascular events.

Sign in / Sign up

Export Citation Format

Share Document