Acceptance and Commitment Therapy for People with Multiple Sclerosis: A NonConcurrent Multiple Baselines Design

2020 ◽  
pp. 1-10
Author(s):  
Ieke Winkens ◽  
Caroline van Heugten ◽  
Ieke Winkens ◽  
Iris de Marez Oyens ◽  
Nicole Geschwind ◽  
...  

Objective: People with multiple sclerosis often suffer from distress, reduced societal participation and low quality of life. Evidence-based psychological treatment options for multiple sclerosis are limited. The aim of this study was to investigate the effectiveness of Acceptance and Commitment Therapy on participation and quality of life for people with multiple sclerosis. Methods: We performed a non-concurrent multiple baselines design study. Six female patients with multiple sclerosis participated. Randomization was implemented by assigning participants randomly to a baseline (waiting) period of three, six or nine weeks. We measured quality of life, and participation on a daily basis, and acceptance and cognitive defusion on a weekly basis. Statistical analyses were performed using randomization tests. Results: After Acceptance and Commitment Therapy, five participants showed statistically significant increases in quality of life and three participants showed statistically significant improvements in participation. Acceptance increased in two patients, and cognitive defusion improved in one patient. Conclusion: Acceptance and Commitment Therapy seems promising for improving the quality of life and participation in people with multiple sclerosis. Mechanisms underlying improvement are not clear yet. Further large-scale controlled studies with more representative samples and a longer follow-up period are justified.

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e012671
Author(s):  
Brian W Slattery ◽  
Laura L O’Connor ◽  
Stephanie Haugh ◽  
Katie Barrett ◽  
Kady Francis ◽  
...  

IntroductionMultimorbidity refers to the presence of two or more chronic health conditions within one person, where no one condition is primary. Research suggests that multimorbidity is highly correlated with chronic pain, which is pain lasting longer than 3 months. Psychotherapeutic interventions for people living with chronic illness have resulted in reduced symptom reporting and improved psychological well-being. There is a dearth of research, however, using online psychotherapy for people living with multimorbidity where chronic pain is a central condition. This study will compare the effectiveness of an online acceptance and commitment therapy (ACT) intervention with a waiting list control condition in terms of improving health-related quality of life (HRQoL) and reducing levels of pain interference in people with chronic pain and at least one other condition.Methods and analysis192 adult participants with non-malignant pain that persists for at least 3 months and at least one other medically diagnosed condition will be randomised to one of two study conditions. The experimental group will undergo an eight-session internet-delivered ACT programme over an 8-week period. A waiting list group will be offered the ACT intervention after the 3-month follow-up period. HRQoL and pain interference will act as the primary outcomes. Data will be analysed using a linear mixed model and adjusted to account for demographic and clinical variables as necessary. A Study Within a Trial will be incorporated to examine the effect on recruitment and retention of showing participants an animated educational video.Ethics and disseminationEthical approval has been granted by the Research Ethics Committee of the National University of Ireland, Galway. Dissemination of results will be via peer reviewed journal articles and conference presentations.Trial registration numberISRCTN22343024.


2010 ◽  
Vol 12 (4) ◽  
pp. 200-206 ◽  
Author(s):  
Sean C. Sheppard ◽  
John P. Forsyth ◽  
Edward J. Hickling ◽  
JeanMarie Bianchi

Multiple sclerosis (MS) is a chronic degenerative disease of the central nervous system for which there is no known cure. The condition is associated with a range of physical, psychological, and emotional difficulties and often results in reduced quality of life (QOL). Acceptance and Commitment Therapy (ACT) is a newer cognitive-behavior therapy that balances 1) mindfulness and acceptance processes with 2) commitment and behavior change processes in the service of reducing suffering while fostering engagement in value-guided actions. The purpose of the present study was to investigate the effectiveness of a half-day ACT workshop focused on teaching mindful acceptance, cognitive defusion, and value-guided action strategies to a group of individuals (N = 15) with MS. The usefulness of the workshop was evaluated in terms of its impact over a 3-month follow-up period on indices of MS-related impairment, emotional distress, and QOL. The results were mixed, with significant improvements observed in the areas of depression, extent of thought suppression, impact of pain on behavior, and QOL but no change in extent of physical symptoms and mindfulness. These results are discussed broadly in terms of developing and improving brief ACT interventions for MS and other chronic illnesses.


Author(s):  
Ghodsieh Ebrahimpour ◽  
Bahram Mirzaeian ◽  
Ramazan Hasanzade

Introdution: Epilepsy is known as a cerebrovascular disorder with a continuing readiness for epileptic seizures and psychological neuropsychological outcomes. The purpose of this study was to investigate the effectiveness of acceptance and commitment therapy on psychological well-being, quality of life and depression in patients with epilepsy. Methods: The study was a quasi- experimental with a pre-test, post-test design with a control group. The statistical population of the study consisted of 76 patients, of whom 20 were selected by available sampling method and they were randomly divided into two experimental and control groups. The experimental group received the acceptance and commitment group therapy in eight sessions each of which in two hours. Before and after the intervention, the Multidimensional Reef psychological well-being questionnaire, Quality of life questionnaire, Beck Depression Inventory was administrated in both groups.  Data were analyzed using covariance test and SPSS20 software. Results: The findings of this study showed that acceptance and commitment based treatment had a significant effect on psychological well-being, quality of life and depression in the level of error less than p <0.0001. And the result of P-value was reported as 42.602, 17. 927, 53.528, respectively. Conclusion: The results of this study show that acceptance and commitment therapy is significantly effective in the patients with epilepsy using techniques such as attention to the present time, acceptance and cognitive impairment in increasing psychological well-being and quality of life and reducing depression. Considering the effect of admission therapy and commitment in using this method at all levels of prevention and treatment of the patients with physical and mental illness seems necessary.


Rheumatology ◽  
2020 ◽  
Vol 59 (Supplement_2) ◽  
Author(s):  
Lorraine Maher-Edwards ◽  
Alexandra Quigley ◽  
David Gillanders ◽  
Nora Ng

Abstract Background Psychiatric comorbidities are common in patients living with rheumatological conditions and are associated with poorer health outcomes and treatment response. The evidence-base for psychological intervention in this population is scarce. Acceptance- and mindfulness-based cognitive therapies are of increasing popularity. Acceptance and Commitment Therapy (ACT) is a psychological therapy with a robust evidence-base for mood disorders and long-term health conditions, in particular in chronic pain populations. ACT aims to help clients to develop skills to identify and let go of unhelpful patterns of symptom control and avoidance so that they can move towards important life areas (values) and goals. Research has consistently shown that higher levels of acceptance (a component of psychological flexibility) in chronic illness is associated with better quality of life and emotional well-being. No studies have looked at the effects of ACT-based interventions in rheumatology. This study aimed to: Develop and pilot I) a 6-week group and II) a brief (up to 6 sessions) one to one intervention based on Acceptance and Commitment Therapy (ACT) in a rheumatology population. Outcomes were evaluated using patient satisfaction data, qualitative feedback and quantitative outcomes using a range of questionnaires measuring mood, quality of life and psychological flexibility. Methods Patients attending a rheumatology psychology service received either group OR brief one to one intervention delivered by a qualified psychologist. Group consisted of 6 sessions; each session was 3 hours (18 hours total). The brief one to one intervention consisted of up to 6 one-hour face to face sessions (max 6 hours total). A range of outcome measures were administered pre- and post-treatment. Paired t-tests were conducted, and the Jacobson and Truax method used to calculate Reliable Change Index and Clinically Significant Change criteria. Effect sizes were calculated using Cohens’ d. For comparison published data in chronic pain populations were used. Results Patients responded well to ACT-based interventions: with improvements in mood, psychological flexibility and quality of life. All effect sizes were large and compared favourably to published trials in chronic pain populations. Group participants showed significant improvements in depression and psychological flexibility pre- to post- treatment. On the other hand, participants who received the brief one to one intervention showed significant improvements on all measures. Overall those who had group therapy showed smaller improvements in outcome measures, rated themselves as less improved and were less satisfied with their therapy than those that received up to 6 sessions of individualised therapy. Conclusion A brief one to one intervention of up to 6 sessions of ACT-based psychological therapy conferred good benefit for a rheumatology population and outperformed group therapy. More studies are needed to understand whether this effect is generalisable and longer-term outcomes. Disclosures L. Maher-Edwards None. A. Quigley None. D. Gillanders None. N. Ng None.


Author(s):  
Christopher D. Graham ◽  
Trudie Chalder ◽  
Michael R. Rose ◽  
Dimitri Gavriloff ◽  
Lance M. McCracken ◽  
...  

AbstractThis study aimed to demonstrate proof of concept and acceptability of a brief acceptance and commitment therapy (ACT)-based guided self-help intervention for improving quality of life (QoL) and mood for people with muscle disorders (MD). A case-series with an AB design was used to assess changes in primary (QoL) and secondary (depression and anxiety) outcome variables across the period of study. Change in the psychological process targeted by ACT – psychological flexibility – was also investigated, to allow insight into possible treatment mechanisms. Post-intervention, participants also completed a brief free-text evaluation. Relative to pre-intervention scores, four (of seven) participants showed varying degrees of improvement in all primary and secondary outcome variables and were thus considered responders. However, consistent concomitant improvements in psychological flexibility were not apparent. Participants reported a mostly positive experience of the intervention; all appeared to complete the intervention, and no adverse events were reported. Nonetheless, there was evidence that those with compromised concentration or who report good initial QoL and low levels of distress may derive less benefit. Although several methodological weaknesses limit the strength of our conclusions, this ACT-based guided self-help intervention shows encouraging utility for improving QoL and mood in MD.


Author(s):  
Narges Fathi ahmadsaraei ◽  
Hamid taher Neshat doost ◽  
Gholam reza Manshaee ◽  
Mohammad ali Nadi ◽  
◽  
...  

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