Technology-Supported Physical Activity Intervention for Metastatic Breast Cancer Survivors

Author(s):  
Cancer ◽  
2016 ◽  
Vol 122 (8) ◽  
pp. 1169-1177 ◽  
Author(s):  
Jennifer A. Ligibel ◽  
Anita Giobbie-Hurder ◽  
Laura Shockro ◽  
Nancy Campbell ◽  
Ann H. Partridge ◽  
...  

Aging ◽  
2020 ◽  
Vol 12 (19) ◽  
pp. 19628-19640
Author(s):  
Xiwen Qian ◽  
Huixun Jia ◽  
Yue Zhang ◽  
Bingqing Ma ◽  
Guoyou Qin ◽  
...  

2018 ◽  
Author(s):  
Lidia Delrieu ◽  
Vincent Pialoux ◽  
Olivia Pérol ◽  
Magali Morelle ◽  
Agnès Martin ◽  
...  

BACKGROUND There is limited knowledge regarding the potential benefits of physical activity in patients with metastatic breast cancer. OBJECTIVE The Advanced stage Breast cancer and Lifestyle Exercise (ABLE) Trial aimed to assess the feasibility of a physical activity intervention in women with metastatic breast cancer and to explore the effects of physical activity on functional, psychological, and clinical parameters. METHODS The ABLE Trial was a single-arm, 6-month intervention study with a home-based, unsupervised, and personalized walking program using an activity tracker. At baseline and 6 months, we assessed anthropometrics, functional fitness, physical activity level, sedentary behavior, quality of life, fatigue, and tumor progression. Paired proportions were compared using the McNemar test and changes of parameters during the intervention were analyzed using the Wilcoxon signed-rank test, the Mann-Whitney test, and Spearman rank correlations. RESULTS Overall, 49 participants (mean age 55 years; recruitment rate 94%) were enrolled and 96% adhered to the exercise prescription (attrition rate 2%). Statistically significant improvements in the 6-minute walking distance test (+7%, <i>P</i>&lt;.001) and isometric quadriceps strength (+22%, <i>P</i>&lt;.001), as well as decreases in body mass index (-2.5%, <i>P</i>=.03) and hip circumference (-4.0%, <i>P</i>&lt;.001) were observed at 6 months. Quality of life remained stable and a nonstatistically significant decrease (-16%, <i>P</i>=.07) in fatigue was observed. CONCLUSIONS The high recruitment and adherence rates suggest the willingness of patients with metastatic breast cancer to participate in a physical activity program. The beneficial outcomes regarding physical fitness and anthropometry of this unsupervised physical activity program may encourage these patients to maintain a physically active lifestyle. Future randomized controlled trials with larger sample sizes are warranted. CLINICALTRIAL ClinicalTrials.gov NCT03148886; https://clinicaltrials.gov/ct2/show/NCT03148886 INTERNATIONAL REGISTERED REPORT RR2-10.2196/10487


2016 ◽  
Vol 34 (3_suppl) ◽  
pp. 175-175
Author(s):  
Jennifer A. Ligibel ◽  
William Thomas Barry ◽  
Kathryn Jean Ruddy ◽  
Mary Greaney ◽  
Shoshana M. Rosenberg ◽  
...  

175 Background: Inactivity is common in breast cancer survivors and has been linked to poor outcomes. Few trials have tested physical activity (PA) interventions in young women with breast cancer, who may face unique PA barriers due to demands of jobs and young families. Methods: Young and Strong was a cluster-randomized study evaluating the effect of education interventions for young breast cancer survivors.Sites were randomized 1:1 to a young women’s intervention (YWI), focused on fertility and other issues facing young women, or to a physical activity intervention (PAI). At PAI sites, providers were instructed to discuss PA with patients, and participants were given materials to encourage PA. PA was measured with the modified Godin Leisure Score Index at baseline, and 3, 6, and 12 months. Medical records were reviewed to assess provider attention to PA. Changes in weekly min of PA were compared between the PAI and YWI groups using general estimating equations to evaluate clustered binary and Gaussian data. Results: 467 patients enrolled between 7/12 -12/13 across 54 sites. Median age at dx was 40yrs (range 22-45). At baseline, participants were moderately active. PA increased in both groups over time (Table); there was no significant difference in PA between groups at any time (all p > 0.1). Provider attention to PA was documented in 74% of participants on PAI and 61% on YWI (p = 0.15), and correlated with PA at 12 months (median 100 min/wk of PA in participants with provider attention to PA vs. 60 min/wk in those without, p = 0.016). Participants who reported reading all or most the PAI materials reported higher levels of PA vs. those who read less (78% vs. 64%, p = 0.05) Conclusions: Young breast cancer survivors assigned to a PA intervention did not increase PA more than those assigned to an intervention focused on young women’s issues. However, the higher levels of PA among women who engaged with the PAI materials and those whose oncology providers addressed PA suggests the importance of enhancing patient and provider engagement with healthy lifestyle information and recommendations. Clinical trial information: NCT01647607. [Table: see text]


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