scholarly journals THE ROLE OF HYPOTHERMIA IN ACUTE ADHESIONS INTESTINAL OBSTRUCTION

ASJ. ◽  
2021 ◽  
Vol 1 (50) ◽  
pp. 13-16
Author(s):  
M. Magomedov ◽  
M. Magomedov

Results of intensive care of 68-patients (39- male, 28 female, aged from 23 to 86 years) with intestinal obstruction are summarized. All the patients were divided into two groups: 1st (study) group consisted of 30 patients who have been treated with hypothermal enteral sanation, patients of 2nd group (38 have been treated with intestinal decompression only. Results of treatment were compared by clinical and laboratory parameters. It is demonstrated that intestinal intubation and hypothermal sanation at acute intestinal obstruction are effective methods for elimination of toxic intestinal contents, prevent ischemic damage and stimulate peristalsis of intestinum. The positive final results after this treatment are demonstrated. Lethality was 10,5 and – 21%.

1967 ◽  
Vol 2 (3) ◽  
pp. 243-243
Author(s):  
S. Matsukura ◽  
A. Shirota ◽  
M. Miki ◽  
K. Naito ◽  
H. Hattori ◽  
...  

Author(s):  
А.А. Коваленко ◽  
В.К. Хугаева

Высокая смертность при хирургическом лечении острой кишечной непроходимости (ОКН) определила поиск новых методов сопутствующей терапии. Обнаруженная ранее высокая эффективность опиоидных пептидов в стимулировании лимфотока в микрососудах брыжейки тонкой кишки у крыс, восстановлении нарушенной микроциркуляцию и снижении смертности при ряде заболеваний, определила цель данного исследования: изучить роль фармакологической стимуляции лимфотока в динамике ОКН. В работе использовали методы: биомикроскопия, лазерная допплеровская флоуметрия брыжейки и стенки тонкой кишки крысы, регистрация сократительной активности лимфатических микрососудов ЛМ методом фотометрии, морфометрия микрососудов, видео- и фотосъемка. Полученные результаты предполагают наличие адаптационной роли у активатора микролимфоциркуляции (опиоидного пептида-171 прямого действия) в комплексном хирургическом лечении ОКН. Однократное орошение пептидом межкишечного анастомоза (после удаления) и поврежденного лигатурой фрагмента кишки (перед зашиванием операционной раны) увеличивало выживаемость животных с ОКН на 23%. У всех выживших животных отмечено восстановление: проходимости кишки, микроциркуляции в кровеносных и лимфатических микрососудах, а также структуры стенки кишки. High mortality in the surgical treatment of acute intestinal obstruction (AIO) has warranted the search for new methods of concomitant therapy. Opioid peptides have proved highly effective in stimulating the lymphatic flow in rat small intestinal mesenteric microvessels, restoring the impaired microcirculation, and reducing mortality in many diseases. This had determined this study objective: to investigate the role of lymphatic stimulation in the dynamics of AIO. The study used methods of biomicroscopy, laser Doppler flowmetry, and histological examination of the mesentery and the small intestinal wall in rats; recording the contractile activity of lymphatic microvessels using photometry; microvessel morphometry; video and photography. The study results suggested an adaptive role of the lymphatic microcirculation activator (direct-action opioid-171) in the complex surgical treatment of AIO. A one-time peptide irrigation of the intestinal anastomosis (after removal) and the intestinal injuried by the ligature (before the surgical wound was sutured) increased the survival of animals with AIO by 23%. In all surviving animals, recovery of the intestinal patency, blood and lymphatic microcirculation, and the intestinal wall structure was observed.


2016 ◽  
Vol 7 (2) ◽  
pp. 40-46
Author(s):  
Dar’ja V Asherova-Jushkova ◽  
Marina A Kovaljova ◽  
Tatjana V Chaparova ◽  
Anna A Shmeljova ◽  
Elena V Gorodova ◽  
...  

The analysis of outcomes of various conditions of the premature neonates with extremely low (ELBW) and the very low body weight (VLBW), who were hospitalized for the last 3 years in the neonate intensive care unit (NICU) of the Yaroslavl regional perinatal center was carried out. Comparison of a lethality of premature with ELBW and VLBW depending on change of approaches to respiratory support, both in the delivery room, and at further stages of treatment, antibacterial strategy and infectious control in the department was performed. Was shown 2,5 fold decrease of mortality due to less invasive surfactant administration (LISA) in a combination with strategy of “the prolonged inspiration” and “open lungs”, the reduction of indications to mechanical ventilation. In study group, with use of LISA technique demonstrated the best survival (16,1 vs 53,0 %, р < 0,0002), smaller need for mechanical ventilation (38,7 vs 86,4 % р < 0,0037), reliable reduction of severe intraventricular hemorrhage (IVH) frequency: IVH3 - 12,9 vs 45,5 % (р < 0013), IVH4 - 6,5 vs 33,3 %(p < 0,0028). In the study group bronchopulmonary dysplasia rate was lower, but retinopathy of prematurity developed more often. The role of microbiological monitoring in NICU, restriction of antibiotic administration indications for reduction of intrahospital infection risks of was shown. Introduction of strict measures of infectious control allowed to reduce incidence of a necrotizing enterocolitis (NEK) from 1,5 to 0,4 % and the related mortality.


1939 ◽  
Vol 110 (3) ◽  
pp. 411-416 ◽  
Author(s):  
JACOB FINE ◽  
LOUIS ROSENFELD ◽  
SAMUEL GENDEL

2019 ◽  
Vol 23 (3) ◽  
pp. 420-424 ◽  
Author(s):  
V.V. Nepomniashchyi

According to literature data acute intestinal obstruction is characterized by a great number of neglected forms comprising 5–70% cases with the given pathology. A number of radiological signs in the way of Kloiber’s bowls and intestinal arches simply confirm this and testify of colon motor activity decompensation. To date there are no objective diagnostic criteria providing indications to intestinal decompression before the operation. Intestinal intubation, its types and indications to its fulfilment are based only on the experience and intuition of the operating surgeon. Aim — to define clinical efficiency of the intestinal wall impaired contractility diagnostics method in the treatment of patients with acute colonic obstruction. Medical histories analysis of 166 patients with obstructive intestinal obstruction was carried out. Assessment of intestinal motor activity compensation was carried out with the help of echographic criteria — the number of enlarged small bowel loops, intestinal lumen width, wall thickness, distance between Kerckring folds, number of peristaltic movements per minute. According to the suggested method 3 groups of patients were distinguished — with compensated motor activity (32 (19%) patients), with sub-compensated motor activity (61 (36.5%) patients) and with intestinal decompensated motor activity (73 (44.4%) patients). Wherein the greater number of patients with obstructive ileus (135 (81%) patients) got into the hospital with sub- and decompensated intestinal motor function. In the group of patients with compensated muscular tone intestinal decompression was not carried out, in the second group with sub-compensated intestinal tone decompression was carried out simultaneously in 13 (7.8%) patients, and in 9 (5.4%) a nasojunal probe was installed for 2–3 days, in the third group intestinal intubation was done in 63 (38%) patients. Post-operative mortality was 3.2%. Thus, echographic criteria allow establishing the degree of intestinal impaired motor function before the operation in patients with acute intestinal obstruction which decompression depends upon its state.


Author(s):  
N. I. Glushkov ◽  
Yu. A. Pakhmutova ◽  
I. I. Belsky ◽  
M. G. Safin ◽  
M. S. Shchur

The results of examination and treatment of 150 patients with acute intestinal obstruction were studied. A reliable relationship was established between the degree of intra-abdominal hypertension and the severity of the condition of patients with acute intestinal obstruction. The results of our study confirm that monitoring intra-abdominal pressure allows diagnosing acute intestinal obstruction at the initial stages of the disease, determining indications for various modes of operative interventions and the timing of their implementation, predicting the development of possible complications and lethality.


2019 ◽  
Vol 27 (1) ◽  
pp. 4-7
Author(s):  
Baymakov S Risbayevich ◽  
Toru Aoyama ◽  
Yunusov S Shevket-Oglu ◽  
Boltayev S Shavkatovich ◽  
Junichi Sakamoto ◽  
...  

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