scholarly journals Effect of Catecholestrogens on Mortality and Liver Lipid Peroxide Level of Mice Irradiated with 60Co .GAMMA.-Ray.

1993 ◽  
Vol 15 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Akira TOMATSU ◽  
Sadaaki KOMURA ◽  
Nobuko OHISHI ◽  
Masami NAKANISHI ◽  
Kunio YAGI
2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Waras Nurcholis ◽  
Chelsea ◽  
Laksmi Ambarsari

Inflammation can cause the formation of prostaglandin and free radicals. In addition, overcome inflammation, a drug used also needs to have an effect as antioxidants to treat the free radicals. This problem can be solved by curcuminoid nanoparticles covered with palmitic acid. This research aims to test the antioxidants effect of curcuminoid nanoparticles covered with palmitic acid from Curcuma to lipid peroxide levels on inflammation rats liver. Antioxidants effect of nanocurcuminoid tested on rats that induced by 1% carrageenan and the liver lipid peroxide measured after 24 hours. Lipid peroxide level was measured with a spectrophotometer in 532 nm wavelength. The average size of curcuminoid nanoparticle covered with palmitic acid is 561.53 nm with an IP score of 0.309. Lipid peroxide level of inflammation rats liver given curcuminoids extract 100 mg/kg BW is 0.27x10-4 nmol/g. It was lower from the nanocurcuminoids 250 mg/kg BW groups which are 1.22 x10-4 nmol/g. Nanocurcuminoids 250 mg/kg BW is 114 times more efficient as an antioxidant than curcuminoids extract 100 mg/kg BW. Keywords: antioxidant, lipid peroxide, nanocurcuminoids


1997 ◽  
Vol 44 (4) ◽  
pp. 701-709 ◽  
Author(s):  
K Yagi

The increase in the lipid peroxide level in the serum and liver of female mice after bilateral ovariectomy evidenced antioxidant activities of female hormones. This increase was abolished upon administration of female hormones. Similar increase in the level of lipid peroxide was observed in the serum of women who had undergone bilateral ovariectomy. Injection of 2-hydroxyestradiol suppressed the increase in the lipid peroxide level in the liver of rats receiving whole-body gamma-ray irradiation. Considering that the mechanism of coronary atherosclerosis is ascribed at least in part to the increased level of lipid peroxides, estrogen therapy could be applied to women who had undergone bilateral ovariectomy prior to menopause or to normal women after menopause. 2-Hydroxyestradiol might be applied also to men.


Author(s):  
Tatsuya Koga ◽  
Yasuyuki Imai ◽  
Tomoji Takamasa ◽  
Koji Okamoto ◽  
Kaichiro Mishima

To delineate the effect of Radiation Induced Surface Activity (RISA) on boiling phenomenon, surface wettability in high-temperature environment or Leidenfrost condition and critical heat flux (CHF) of oxide metals irradiated by gamma rays were investigated. When the temperature of the heating surface reaches the wetting limit temperature, water-solid contact vanishes because of a stable vapor film between the droplet and the metal surface, i.e., a Leidenfrost condition. The wetting limit temperature increased with integrated irradiation dose. The CHF of oxidized titanium was improved up to 100% after 800 kGy 60Co gamma ray irradiated. Radiation Induced Boiling Enhancement (RIBE) phenomenon was firstly confirmed through the experiments.


1992 ◽  
Vol 70 (3-4) ◽  
pp. 259-262 ◽  
Author(s):  
Nahide Gokcora ◽  
Sadi Gundogdu ◽  
Aysel Aricioglu ◽  
Deniz Erbas ◽  
Osman Durmus ◽  
...  

Epidermal growth factor (EGF) is a growth-promoting polypeptide which is found in highest levels in male mice in the submaxillary gland. It may also be a key factor in regeneration of the liver. We performed experiments with 18 male Wistar rats, divided into three groups. Hepatic left lobectomy (%30) was performed on the first group of rats. This group received an intraperitoneal injection of EGF for 7 days. The second group was the control group into which normal saline was injected for 7 days. The third group was sham-operated. On days 5 and 7 tomographic studies of liver were performed. On day 7 EGF levels, lipid peroxidation, and glutathione in liver were measured in all of the rats. While serum EGF levels did not show any significant change, the levels of lipid peroxide were decreased and glutathione was increased. Tomographic measurements indicated that administration of EGF increased the amount of regeneration.Key words: epidermal growth factor, liver lobectomy, lipid peroxide, glutathione, radioimmunoassay.


2019 ◽  
Vol 8 (7) ◽  
pp. Q3041-Q3045 ◽  
Author(s):  
Jiancheng Yang ◽  
Gregory J. Koller ◽  
Chaker Fares ◽  
F. Ren ◽  
S. J. Pearton ◽  
...  
Keyword(s):  

2019 ◽  
Vol 186 (2-3) ◽  
pp. 235-238
Author(s):  
Norman Durný

Abstract The primary standard for air kerma of the Slovak Institute of Metrology (SMU) as a part of national standard of dosimetric quantities of gamma radiation NE028/02, based on cylindrical graphite walled cavity ionization chamber was established in 2002 for the 60Co gamma ray beams. Since then the main role of SMU was to continuously maintain, develop and refurbish the standard with related accessory to ensure international equivalence. Since 2002, a re-evaluation of the active volume of the ionizing chamber, correction factors, the key data, due to adoption of ICRU Report 90(1), and changes of the calibrations methods and corrections of the equipment were made to obtain improved parameters. The range was extended for 137Cs gamma ray beams and key comparisons with the Bureau International des Poids et Mesures (BIPM) were performed. ICRU Report 90(1) implementation led to a decrease of the Gray of −0.84% for 60Co and −0.80% for 137Cs.


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