scholarly journals Study on the Causes, Types, and Mechanisms of Childhood Injuries-Age and Disease Specificity

JMA Journal ◽  
2021 ◽  
Vol 4 (3) ◽  
pp. 246-253
Author(s):  
George Hug ◽  
William K. Schubert ◽  
Shirley Soukup

McKusick subdivided the syndrome of mucopolysaccharidoses into six types according to clinical, roentenographic, and genetic criteria and to the kind of mucopolysaccharide(s) excreted in the urine (1). Deficient activity of a lysosomal enzyme, (β-galactosidase, has recently been reported in types I, II and III of mucopolysaccharidoses as well as in generalized gangliosidosis (2). This apparent lack of disease specificity makes the enzymatic deficiency difficult to interpret. Nevertheless, the involvement of a lysosomal enzyme tends to characterize these disorders as lysosomal diseases.


Author(s):  
Prasanthi Puvanachandra ◽  
Charles Ssemugabo ◽  
Bonny Balugaba ◽  
Anthony Mugeere ◽  
Abdul Bachani ◽  
...  

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e039243
Author(s):  
Adam Gyedu ◽  
Barclay T Stewart ◽  
Easmon Otupiri ◽  
Kajal Mehta ◽  
Peter Donkor ◽  
...  

ObjectiveWe aimed to describe the incidence of childhood household injuries and prevalence of modifiable household risk factors in rural Ghana to inform prevention initiatives.Setting357 randomly selected households in rural Ghana.ParticipantsCaregivers of children aged <5 years.Primary and secondary outcome measuresChildhood injuries that occurred within 6 months and 200 metres of the home that resulted in missed school/work, hospitalisation and/or death. Sampling weights were applied, injuries were described and multilevel regression was used to identify risk factors.ResultsCaregivers from 357 households had a mean age of 35 years (SD 12.8) and often supervised ≥2 children (51%). Households typically used biomass fuels (84%) on a cookstove outside the home (79%). Cookstoves were commonly <1 metre of the ground (95%). Weighted incidence of childhood injury was 542 per 1000 child-years. Falls (37%), lacerations (24%), burns (12%) and violence (12%) were common mechanisms. There were differences in mechanism across age groups (p<0.01), but no gender differences (p=0.25). Presence of older children in the home (OR 0.15, 95% CI 0.09 to 0.24; adjusted OR (aOR) 0.26, 95% CI 0.13 to 0.54) and cooking outside the home (OR 0.28, 95% CI 0.19 to 0.42; aOR 0.25, 95% CI 0.13 to 0.49) were protective against injury, but other common modifiable risk factors (eg, stove height, fuel type, secured cabinets) were not.ConclusionsChildhood injuries occurred frequently in rural Ghana. Several common modifiable household risk factors were not associated with an increase in household injuries. Presence of older children was a protective factor, suggesting that efforts to improve supervision of younger children might be effective prevention strategies.


Virology ◽  
2007 ◽  
Vol 362 (1) ◽  
pp. 179-191 ◽  
Author(s):  
Karina Dalsgaard Sørensen ◽  
Sandra Kunder ◽  
Leticia Quintanilla-Martinez ◽  
Jonna Sørensen ◽  
Jörg Schmidt ◽  
...  

2013 ◽  
Vol 10 (4) ◽  
pp. 367
Author(s):  
IssaAbdul Razaq Esin ◽  
Sikiru Alabi ◽  
OluwagbemigaAbdul Razzaq Lawal

2016 ◽  
Vol 22 (Suppl 2) ◽  
pp. A330.1-A330 ◽  
Author(s):  
Huan He ◽  
Yuen W Hung ◽  
Isaac M Botchey ◽  
Abdul M Bachani ◽  
Hassan Saidi ◽  
...  

2007 ◽  
Vol 14 (4) ◽  
pp. 262-263
Author(s):  
Christos Christoforidis ◽  
Antonis Kambas

Author(s):  
He L ◽  
◽  
Jia X ◽  
Yu L ◽  
◽  
...  

Type 1 Diabetes (T1D) is one of the most common chronic diseases in childhood, which is caused by destruction of insulinproducing pancreatic beta cells. Its incidence increases 3-5% annually and doubles every 20 years [1,2]. On one hand, acute and chronic complications of T1D seriously affect the quality of life and even life span of patients. On the other hand, prognosis can greatly be improved when the disease prediction and closely monitoring are applied, leading to earlier diagnosis and treatment [3]. Islet Autoantibodies (IAbs), as most reliable biomarkers at present for islet autoimmunity, precede clinical T1D by years and play an essential role in prediction and clinical diagnosis of T1D [4,5].


2016 ◽  
Vol 1 ◽  
pp. 58-62
Author(s):  
Sylwia Wieder-Huszla ◽  
Agata Hrynkiewicz ◽  
Jolanta Tuszyńska-Stasiak ◽  
Anna Jurczak ◽  
Katarzyna Augustyniuk ◽  
...  

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