Body condition score and plane of nutrition prepartum affect adipose tissue transcriptome regulators of metabolism and inflammation in grazing dairy cows during the transition period

The aim of the present study was to evaluate the potential for diagnosis of fatty liver by means of ultrasonographic measurement of liver and perivisceral adipose tissue as an alternative to blood indicators of lipomobilization and liver biopsy in periparturient high-yielding dairy cows. Thirty cows were enrolled and divided into two groups. The evaluation of body condition score (BCS), non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), liver and perivisceral adipose tissue ultrasonographic measurement and histological liver lipid content (GdL) was performed at 15 ± 5 d prepartum (T0), 10 ± 2 d postpartum (T1), 30 ± 2 d postpartum (T2) and 50 ± 2 d postpartum (T3). Mesenteric fat thickness (the thickness of the perivascular adipose tissue) measured on ultrasound was shown to be an independent determinant of fatty liver. The cut-off of the ultrasonographic evaluation of the liver may be useful as a first and practical approach in identifying fatty liver. In conclusion, a non-invasive and reliable diagnostic method for predicting the risk of fatty liver in high yielding dairy cows has been demonstrated.

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Body condition score at calving affects systemic and hepatic transcriptome indicators of inflammation and nutrient metabolism in grazing dairy cows

Journal of Dairy Science ◽

10.3168/jds.2014-8584 ◽

2015 ◽

Vol 98 (2) ◽

pp. 1019-1032 ◽

Cited By ~ 53

Author(s):

H. Akbar ◽

T.M. Grala ◽

M. Vailati Riboni ◽

F.C. Cardoso ◽

G. Verkerk ◽

...

Keyword(s):

Dairy Cows ◽

Body Condition ◽

Body Condition Score ◽

Nutrient Metabolism ◽

Condition Score ◽

Grazing Dairy Cows ◽

Hepatic Transcriptome

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Nutritional regulation of body condition score at the initiation of the transition period in primiparous and multiparous dairy cows under grazing conditions: milk production, resumption of post-partum ovarian cyclicity and metabolic parameters

animal ◽

10.1017/s175173111100142x ◽

2012 ◽

Vol 6 (2) ◽

pp. 292-299 ◽

Cited By ~ 26

Author(s):

M.L. Adrien ◽

D.A. Mattiauda ◽

V. Artegoitia ◽

M. Carriquiry ◽

G. Motta ◽

...

Keyword(s):

Dairy Cows ◽

Milk Production ◽

Body Condition ◽

Transition Period ◽

Body Condition Score ◽

Post Partum ◽

Metabolic Parameters ◽

Nutritional Regulation ◽

Condition Score ◽

Ovarian Cyclicity

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Increase in white blood cell counts by pegbovigrastim in primiparous and multiparous grazing dairy cows and the interaction with prepartum body condition score and non-esterified fatty acids concentration

PLoS ONE ◽

10.1371/journal.pone.0245149 ◽

2021 ◽

Vol 16 (1) ◽

pp. e0245149

Author(s):

Joaquín Barca ◽

Ynte H. Schukken ◽

Ana Meikle

Keyword(s):

Blood Cell ◽

Dairy Cows ◽

Body Condition ◽

White Blood Cell ◽

Body Condition Score ◽

Negative Association ◽

Nefa Concentration ◽

Condition Score ◽

Peg Treatment ◽

Grazing Dairy Cows

The objective of this study was to determine if parity affected the effect of pegbovigrastim (PEG) treatment on white blood cell (WBC) counts in grazing dairy cows. Additionally, the association of prepartum body condition score (BCS) and non-esterified fatty acid (Pre-NEFA) concentration with WBC counts was investigated. The effect of early-lactation disease was included in the statistical analysis. A randomized controlled trial on four commercial grazing dairy farms was performed. Holstein primiparous (Control = 87, PEG = 89) and multiparous (Control = 181, PEG = 184) cows were randomly assigned to one of two treatments: first PEG dose 8 ± 5 (mean ± SD) days before the expected calving date and a second dose within 24 h after calving (PEG) compared to untreated controls (Control). Treatment effects were evaluated with mixed linear regression models. Treatment with PEG increased WBC, neutrophil, lymphocyte and monocyte counts at 6 ± 1 (mean ± SD) days in milk. Parity, BCS and their interactions with treatment were not associated with WBC counts. In control cows, Pre-NEFA concentration was associated with reduced WBC, neutrophil and lymphocyte counts and tended to be associated with reduced monocyte counts. Pegbovigrastim treatment reversed the negative association of Pre-NEFA concentration with neutrophil and monocyte counts and tended to reverse the negative association of Pre-NEFA concentration with WBC counts. In the PEG treated group, cows diagnosed with retained placenta or metritis showed lower neutrophil counts when compared to PEG treated cows without these clinical diseases. These data confirm that PEG treatment increases WBC, neutrophil, lymphocyte and monocyte counts in grazing dairy cows and that this effect is independent of parity. Pegbovigrastim treatment reversed the negative association of Pre-NEFA concentration with neutrophil and monocyte counts, and tended to reverse the negative association of Pre-NEFA concentration with WBC counts.

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