scholarly journals Association of Growth Hormone Loci with Milk Yield Traits in Holstein Bulls

1999 ◽  
Vol 82 (4) ◽  
pp. 788-794 ◽  
Author(s):  
N. Vukasinovic ◽  
S.K. Denise ◽  
A.E. Freeman
Keyword(s):  
Growth Hormone ◽  
Milk Yield ◽  
Yield Traits ◽  
Holstein Bulls

Relationships between polymorphisms of growth hormone, leptin and myogenic factor 5 genes with some milk yield traits in Holstein dairy cows

2018 ◽  
Vol 72 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Jale Metin Kiyici ◽  
Korhan Arslan ◽  
Bilal Akyuz ◽  
Mahmut Kaliber ◽  
Esma Gamze Aksel ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Dairy Cows ◽  
Milk Yield ◽  
Yield Traits ◽  
Myogenic Factor ◽  
Holstein Dairy Cows

scholarly journals Association of growth hormone (GH), insulin-like growth factor 2 (IGF2) and progesterone receptor (PGR) genes with some productive traits in Gabali rabbits

2020 ◽  
Vol 28 (3) ◽  
pp. 135
Author(s):  
S.I. Ramadan ◽  
E.A. Manaa ◽  
M.E. El-Attrony ◽  
A.G. EL Nagar
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Progesterone Receptor ◽  
Litter Size ◽  
Milk Yield ◽  
The Other ◽  
Daily Weight Gain ◽  
Yield Traits ◽  
Insulin Like Growth Factor ◽  
Production Traits

<p>The objectives of the present study were 1) to evaluate the polymorphism of growth hormone(GH), insulin-like growth factor 2 (IGF2) and progesterone receptor (PGR) genes in Sinai Gabali rabbits, and 2) to assess their associations with growth, litter size and milk production traits in Sinai Gabali rabbits. The C&gt;T, A&gt;Del and A&gt;G single nucleotide polymorphisms of GH, IGF2 and PGR genes were genotyped by polymerase chain reaction-restriction fragment length polymorphism using BstUI, HpyF31 and BsaI restriction enzymes, respectively. The C/T genotype of GH gene recorded the heaviest body weights for body weight (BW) at 8 wk (1190.22±19.29 g) and 12 wk of age (1842.46±30.19 g) and recorded the largest litter size at birth (LSB: 7.37±0.12 kits) traits. The Del/Del genotype of IGF2 gene showed the superiority over the other genotypes for BW at 4 wk (507.17±8.87 g), 8 wk (1239.39±14.0 g), and 12 wk of age (1950.15±18.1 g), as well as for daily weight gain from 4 to 8 wk (26.05±0.37 g/d), and from 8 to 12 wk of age (25.48±0.56 g/d) traits. The G/G genotype of the PGR gene showed superiority for LSB (7.51±0.13 kits) and litter size at weaning (6.53±0.14 kits) traits over the other genotypes. Regarding milk yield traits; the C/C, A/A and A/A genotypes of GH, IGF2 and PGR genes yielded more milk compared to the other genotypes. The means of total milk yield in 28 d for these genotypes were 2936±29 g, 2921±43 g and 2930±35 g, respectively. Thus, GH, IGF2 and PGR genes might be useful for marker-assisted selection programmes for improvement of rabbit growth, litter size and milk yield traits.</p>

scholarly journals Sequence Variations in the Bovine Growth Hormone Gene Characterized by Single-Strand Conformation Polymorphism (SSCP) Analysis and Their Association with Milk Production Traits in Holsteins

Genetics ◽  
1996 ◽  
Vol 144 (4) ◽  
pp. 1809-1816 ◽  
Author(s):  
Jianbo Yao ◽  
Samuel E Aggrey ◽  
David Zadworny ◽  
J Flan Hayes ◽  
Urs Kühnlein
Keyword(s):  
Growth Hormone ◽  
Milk Production ◽  
Milk Yield ◽  
Single Strand Conformation Polymorphism ◽  
Sscp Analysis ◽  
Bovine Growth Hormone ◽  
Production Traits ◽  
Milk Production Traits ◽  
Sequence Variations ◽  
Conformation Polymorphism

Sequence variations in the bovine growth hormone (GH) gene were investigated by single strand conformation polymorphism (SSCP) analysis of seven amplified fragments covering almost the entire gene (2.7 kb). SSCPs were detected in four of these fragments and a total of six polymorphisms were found in a sample of 128 Holstein bulls. Two polymorphisms, a T→C transition in the third intron (designated GH4.1) and an A→C transversion in the fifth exon (designated GH6.2), were shown to be associated with milk production traits. GH4.1c/GH4.1c bulls had higher milk yield than GH4.1c/GH4.1t (P ≤ 0.005) and GH4.1t/GH4.1t (P ≤ 0.0022) bulls. GH4.1c/GH4.1c bulls had higher kg fat (P ≤ 0.0076) and protein (P ≤ 0.0018) than GH4.1c/GH4.1t bulls. Similar effects on milk production traits with the GH6.2 polymorphism were observed with the GH6.2a allele being the favorable allele. The average effects of the gene substitution for GH4.1 and GH6.2 are similar, with ±300 kg for milk yield, ±8 kg for fat content and ±7 kg for protein content per lactation. The positive association of GH4.1c and GH6.2a with milk production traits may be useful for improving milk performance in dairy cattle.

THE MAINTENANCE OF LACTATION IN THE RABBIT AFTER HYPOPHYSECTOMY

1969 ◽  
Vol 43 (4) ◽  
pp. 651-662 ◽  
Author(s):  
A. T. COWIE ◽  
P. E. HARTMANN ◽  
A. TURVEY
Keyword(s):  
Growth Hormone ◽  
Immune Responses ◽  
Milk Yield ◽  
Human Growth Hormone ◽  
Synergistic Effects ◽  
Human Growth ◽  
Milk Composition ◽  
Bovine Growth Hormone ◽  
Partial Recovery ◽  
Milk Secretion

SUMMARY Twenty-one rabbits were hypophysectomized during the second week of lactation. Hypophysectomy inhibited milk secretion within 3–7 days. Restoration of the milk yield to pre-operative levels was obtained when daily injections of either sheep prolactin (50 or 100 i.u.) or human growth hormone (HGH) (2·5 or 5 mg.) were administered; partial recovery of the milk yield was obtained with 25 i.u. sheep prolactin/day or 1·25 mg. HGH/day. Neither bovine growth hormone (BGH), adrenocorticotrophin (ACTH) nor cortisol acetate had any significant restorative effects on milk secretion or synergistic effects when combined with sheep prolactin or HGH. The probable development of immune responses to sheep prolactin and HGH was observed. After hypophysectomy, changes in milk composition were found which were similar in trend to the more gradual normal changes observed in late lactation. Sheep prolactin and HGH restored the composition of the milk as well as the yields to normal levels, and both hormones caused rapid increases in lactose yields. The pigeon crop-stimulating potency of the HGH preparation was low (equivalent to 3·7 i.u. sheep prolactin/mg.), yet its lactogenic and galactopoietic potencies were high thus emphasizing the unreliability of assessing the mammotrophic potencies of HGH preparations in birds.

scholarly journals Quantitative Trait Locus-by-Environment Interaction for Milk Yield Traits onBos taurusAutosome 6

Genetics ◽  
2008 ◽  
Vol 179 (3) ◽  
pp. 1539-1546 ◽  
Author(s):  
Marie Lillehammer ◽  
Mike E. Goddard ◽  
Heidi Nilsen ◽  
Erling Sehested ◽  
Hanne Gro Olsen ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Milk Yield ◽  
Quantitative Trait ◽  
Environment Interaction ◽  
Yield Traits ◽  
Trait Locus

scholarly journals Buffering Agent-Induced Lactose Content Increases via Growth Hormone-Mediated Activation of Gluconeogenesis in Lactating Goats

2018 ◽  
pp. 317-329 ◽  
Author(s):  
L. LI ◽  
M. L. HE ◽  
Y. LIU ◽  
Y. S. ZHANG
Keyword(s):  
Growth Hormone ◽  
Milk Yield ◽  
Phosphoenolpyruvate Carboxykinase ◽  
Volatile Fatty Acids ◽  
Glucose Transporter ◽  
Glucose Content ◽  
Blood Concentrations ◽  
Lactating Goats ◽  
Buffering Agent ◽  
Lactose Synthesis

Dairy goats are often fed a high-concentrate (HC) diet to meet their lactation demands; however, long-term concentrate feeding is unhealthy and leads to milk yield and lactose content decreases. Therefore, we tested whether a buffering agent is able to increase the output of glucose in the liver and influence lactose synthesis. Eight lactating goats were randomly assigned to two groups: one group received a HC diet (Concentrate : Forage = 6:4, HG) and the other group received the same diet with a buffering agent added (0.2 % NaHCO3, 0.1 % MgO, BG) over a 19-week experimental period. The total volatile fatty acids and lipopolysaccharide (LPS) declined in the rumen, which led the rumen pH to become stabile in the BG goats. The milk yield and lactose content increased. The alanine aminotransferase, aspartate transaminase, alkaline phosphatase, pro-inflammatory cytokines, LPS and lactate contents in the plasma significantly decreased, whereas the prolactin and growth hormone levels increased. The hepatic vein glucose content increased. In addition, pyruvate carboxylase (PC), phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6PC) expression in the liver was significantly up-regulated. In the mammary glands, the levels of glucose transporter type 1, 8, 12 as well as of sodium-glucose cotransporter 1 increased. Cumulative buffering agent treatment increased the blood concentrations of glucose via gluconeogenesis and promoted its synthesis in the liver. This treatment may contribute to the increase of the milk yield and lactose synthesis of lactating goats.

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