scholarly journals Mapping visuospatial and self-motion perception functions in the left parietal lobe

2018 ◽  
Vol 45 (VideoSuppl2) ◽  
pp. V8 ◽  
Author(s):  
Carlos Velásquez ◽  
Elsa Goméz ◽  
Juan Martino
Keyword(s):  
Motion Perception ◽  
Parietal Lobe ◽  
Spatial Neglect ◽  
Low Grade ◽  
Language Mapping ◽  
Subcortical Stimulation ◽  
The Right ◽  
Glioma Resection ◽  
Self Motion ◽  
Stimulation Of

Parietal lobe functions include somesthesia, language, calculation, self-motion perception, and visuospatial awareness. In this video, the authors show the intraoperative mapping of a left parietal lobe for a low-grade glioma resection. Standard sensory and language mapping were performed. Interestingly, by using the “Line Bisection” task, subcortical stimulation of the gyrus angularis was repeatedly associated with ipsilateral spatial neglect, often described in the right parietal lobe. In a similar way, subcortical stimulation in a more posterior point elicited episodes of vertigo, probably due to stimulation of the superior longitudinal fasciculus. Both findings were useful to define the functional limit of the resection.The video can be found here: https://youtu.be/qgGDRW_6u0A.

scholarly journals Intraoperative cortical mapping of visuospatial functions in parietal low-grade tumors: changing perspectives of neurophysiological mapping

2013 ◽  
Vol 34 (2) ◽  
pp. E4 ◽  
Author(s):  
Andrea Talacchi ◽  
Giovanna Maddalena Squintani ◽  
Barbara Emanuele ◽  
Vincenzo Tramontano ◽  
Barbara Santini ◽  
...  
Keyword(s):  
Parietal Lobe ◽  
Spatial Neglect ◽  
Cortical Mapping ◽  
Neurophysiological Monitoring ◽  
Low Grade ◽  
Language Functions ◽  
First Case ◽  
Visuospatial Functions ◽  
The Right ◽  
Language Areas

Object The aim of this study was to explore the feasibility of intraoperative visuospatial mapping with the same criteria currently used to define essential language areas. Methods The authors compared surgical procedures in 2 patients with similar tumors (Grade II oligodendroglioma in the right parietal lobe) undergoing awake, image-assisted surgery for lesion removal with intraoperative neurophysiological monitoring. The line bisection task was used in both patients but with different criteria. Results In the first case, the authors respected any area, even within the tumor, where significant interference was found (a stimulation-induced error in 2 of 3 applications defined an essential area). In the second case, they removed 1 essential area located in the tumor and recorded an uneventful clinical response soon thereafter. They continued to monitor the patient without stimulation and stopped the resection when the patient was close to the criteria valid for defining spatial neglect. The signs of spatial neglect were present for 3 days postoperatively and then cleared spontaneously. Subtotal tumor removal was achieved in both cases. Conclusions Evidence in the present study reveals that areas for visuospatial functions cannot be assessed with the same criteria used for language functions, since essential areas located in the tumor can be safely removed.

scholarly journals Predictors of stimulation-induced seizures during perirolandic glioma resection using intraoperative mapping techniques

2021 ◽  
Vol 12 ◽  
pp. 117
Author(s):  
Ahmed A. Morsy ◽  
Ayman M. Ismail ◽  
Yasser M. Nasr ◽  
Salwa H. Waly ◽  
Esam A. Abdelhameed
Keyword(s):  
Neurological Status ◽  
Extent Of Resection ◽  
Low Grade Glioma ◽  
Low Grade ◽  
Motor Responses ◽  
Intraoperative Mapping ◽  
Subcortical Stimulation ◽  
The Mean ◽  
Mapping Techniques ◽  
Glioma Resection

Background: Intraoperative mapping techniques maximize safety and efficacy during perirolandic glioma resection but may induce seizures and limit the procedure. We aim to report the incidence and predictors of stimulation-induced seizures during mapping either patient is awake or under general anesthesia (GA). Methods: Retrospective analysis of 64 patients (40 awake and 24 GA) with perirolandic glioma underwent resection using intraoperative mapping techniques between 2014 and 2019. Preoperative data, operative details, postoperative neurological status, and extent of resection (EOR) were analyzed. Predictors of intraoperative seizures were assessed. Results: The mean cortical and subcortical stimulation intensities needed to evoke motor responses were significantly lower in awake cases than in GA patients (4.9 ± 0.42 vs. 8.9 ± 1.2 mA) and (8.3 ± 0.62 vs. 12.1 ± 1.1 mA), respectively (P = 0.01). Incidence of intraoperative seizures was lower but statistically non-significant in awake cases (10% vs. 12.5%) (P = 0.76). Preoperative multiple antiepileptic drugs (AEDs) (P = 0.03) and low-grade glioma (P = 0.04) were statistically significant predictors for intraoperative seizures. Mean EOR in awake cases was 92.03% and 90.05% in GA cases (P = 0.23). Postoperative deficits were permanent after 3 months only in 5% of awake patients versus 8.3% of GA group (P = 0.59). Conclusion: Awake craniotomy with intraoperative mapping can be done safely for perirolandic gliomas with lower but statistically nonsignificant incidence of intraoperative seizures and this could be attributed to statistically significant lower stimulation intensities required for mapping. Preoperative multiple AEDs and low-grade glioma are significant predictors for intraoperative seizures.

Damage to the right superior longitudinal fasciculus in the inferior parietal lobe plays a role in spatial neglect

2009 ◽  
Vol 47 (12) ◽  
pp. 2600-2603 ◽  
Author(s):  
N. Shinoura ◽  
Y. Suzuki ◽  
R. Yamada ◽  
Y. Tabei ◽  
K. Saito ◽  
...  
Keyword(s):  
Parietal Lobe ◽  
Spatial Neglect ◽  
Superior Longitudinal Fasciculus ◽  
Inferior Parietal Lobe ◽  
The Right

Priming of Color and Position during Visual Search in Unilateral Spatial Neglect

2005 ◽  
Vol 17 (6) ◽  
pp. 859-873 ◽  
Author(s):  
Árni Kristjánsson ◽  
Patrik Vuilleumier ◽  
Paresh Malhotra ◽  
Masud Husain ◽  
Jon Driver
Keyword(s):  
Visual Search ◽  
Target Location ◽  
Parietal Lobe ◽  
Spatial Neglect ◽  
Healthy Controls ◽  
Unilateral Spatial Neglect ◽  
Inferior Parietal Lobe ◽  
Color Priming ◽  
The Right ◽  
Singleton Target

We examined priming of visual search by repeated target location or color in two patients with left visual neglect and extinction, following strokes centered on the right inferior parietal lobe. Both patients, like the healthy controls we tested, showed intact priming, with performance speeded when either the location or color of a singleton target was repeated over successive trials in a standard search condition (Experiment 1). This was observed both from and to targets on the contralesional (left) side. Moreover, priming of search was still observed even when a return of fixation back to display-center was required between successive trials (Experiment 2). When briefer displays were used (Experiment 3), the patients often failed to detect left targets. This situation revealed an important dissociation: Whereas location priming only arose from preceding left targets that had been consciously detected, color priming (possibly arising within the intact ventral stream) did not depend on awareness of the preceding target. There was considerable color priming from missed targets. These findings demonstrate relatively intact priming of visual search by color and location in patients with right parietal damage, and also reveal that location priming may differ from color priming in requiring awareness.

scholarly journals Neuropsychological Outcomes After Awake Resections of Right Frontal IDH-Mutated Glioma: Insights From a Consecutive Series of 20 Cases.

2021 ◽  
Author(s):  
Marion Barberis ◽  
Isabelle Poisson ◽  
Valentine Facque ◽  
Sophie Letrange ◽  
Cécile Prévost-Tarabon ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Cognitive Deficits ◽  
Spatial Neglect ◽  
Awake Surgery ◽  
Consecutive Series ◽  
Low Grade ◽  
Worth Living ◽  
Behavioral Impairment ◽  
Dysexecutive Syndrome ◽  
The Right

Abstract Background Awake surgery for low-grade gliomas is currently considered the best procedure to improve the extent of resection and guarantee a "worth living life" for patients, meaning avoiding not only motor but also cognitive deficits. However, tumors located in the right hemisphere, especially in the right frontal lobe, are still rarely operated on in awake condition; one of the reasons possibly being that there is little information in the literature describing the rates and nature of long-lasting neuropsychological deficits following resection of right frontal glioma. Objective To investigate long-term cognitive deficits after awake surgery in right frontal IDH-mutated glioma. Methods We retrospectively analyzed a consecutive series of awake surgical resections between 2012 and 2020 for right frontal IDH-mutated glioma. We studied the patients' subjective complaints and objective neuropsychological evaluations, both before and after surgery. Our results were then put in perspective with the literature. Results Twenty surgical cases (including 5 cases of redo surgery) in eighteen patients (medium age: 42.5 [range 26–58]) were included in the study. The median preoperative volume was 37 cc; WHO grading was II, III and IV in 70%, 20%, and 10% of cases, respectively. Preoperatively, few patients had related subjective cognitive or behavioral impairment, while evaluations revealed mild deficits in 45% of cases, most often concerning executive functions, attention, working memory and speed processing. Immediate postoperative evaluations showed severe dysexecutive syndrome in 75% of cases but also attentional deficits (65%), spatial neglect (60%) and behavioral disturbances (apathy, aprosodia/amimia, emotional sensitivity, anosognosia). Four months after surgery, although psychometric z-scores were unchanged at the group level, individual evaluations showed a slight decrease in performance in 9/20 cases (dysexecutive syndrome, speed processing, attention, semantic cognition, social cognition). Conclusion Our results are generally consistent with those of the literature, confirming that the right frontal lobe is a highly eloquent area and highlighting the importance of operating these patients in awake conditions.

scholarly journals Increased Anxiety After Stimulation of the Right Inferior Parietal Lobe and the Left Orbitofrontal Cortex

2020 ◽  
Vol 11 ◽  
Author(s):  
Matthias Grieder ◽  
Philipp Homan ◽  
Andrea Federspiel ◽  
Claus Kiefer ◽  
Gregor Hasler
Keyword(s):  
Orbitofrontal Cortex ◽  
Parietal Lobe ◽  
Inferior Parietal Lobe ◽  
The Right ◽  
Stimulation Of

Electrostimulation Mapping of Spatial Neglect

Neurosurgery ◽  
2011 ◽  
Vol 69 (6) ◽  
pp. 1218-1231 ◽  
Author(s):  
Franck-Emmanuel Roux ◽  
Olivier Dufor ◽  
Valérie Lauwers-Cances ◽  
Leila Boukhatem ◽  
David Brauge ◽  
...  
Keyword(s):  
Right Hemisphere ◽  
Parietal Lobe ◽  
Group Analysis ◽  
Posterior Part ◽  
Line Bisection ◽  
Spatial Neglect ◽  
Control Group ◽  
Cortical Areas ◽  
Specificity And Sensitivity ◽  
The Right

Abstract BACKGROUND Cortical and subcortical electrostimulation mapping during awake brain surgery for tumor removal is usually used to minimize deficits. OBJECTIVE To use electrostimulation to study neuronal substrates involved in spatial awareness in humans. METHODS Spatial neglect was studied using a line bisection task in combination with electrostimulation mapping of the right hemisphere in 50 cases. Stimulation sites were identified with Talairach coordinates. The behavioral effects induced by stimulation, especially eye movements and deviations from the median, were quantified and compared with preoperative data and a control group. RESULTS Composite and highly individualized spatial neglect maps were generated. Both rightward and leftward deviations were induced, sometimes in the same patient but for different stimulation sites. Group analysis showed that specific and reproducible line deviations were induced by stimulation of discrete cortical areas located in the posterior part of the right superior and middle temporal gyri, inferior parietal lobe, and inferior postcentral and inferior frontal gyri (P > .05). Fiber tracking identified stimulated subcortical areas important to spare as sections of fronto-occipital and superior longitudinal II fascicles. According to preoperative and postoperative neglect battery tests, the specificity and sensitivity of intraoperative line bisection tests were 94% and 83%, respectively. CONCLUSION In humans, discrete cortical areas that are variable in location between individuals but mainly located within the right posterior Sylvian fissure sustain visuospatial attention specifically toward the contralateral or ipsilateral space direction. Line bisection mapping was found to be a reliable method for minimizing spatial neglect caused by brain tumor surgery.

scholarly journals Impaired Set-Shifting from Dorsal Stream Disconnection: Insights from a European Series of Right Parietal Lower-Grade Glioma Resection

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3337
Author(s):  
Suzanne L. Hartung ◽  
Emmanuel Mandonnet ◽  
Philip de Witt Hamer ◽  
Martin Klein ◽  
Michel Wager ◽  
...  
Keyword(s):  
Stroop Task ◽  
Right Hemisphere ◽  
Parietal Lobe ◽  
Dorsal Stream ◽  
Awake Surgery ◽  
Lateral Part ◽  
Low Grade ◽  
Lower Grade ◽  
Set Shifting ◽  
The Right

Awake surgery with cognitive monitoring has increasingly been implemented to preserve brain networks and functionality. More recently, not only surgery in the left but also in the right hemisphere, i.c., the parietal lobe, was associated with potential risk for deficits in cognitive functions, such as cognitive flexibility. In this explorative pilot study, we compare cognitive performance more than three months after surgery with baseline measurements and explore the association between cognitive decline and subcortical tracts that may have been severed during surgery in the right hemisphere. Twenty-two patients who underwent surgery for a right parietal low-grade glioma were assessed pre- and postoperatively using the Trail Making Test and the Stroop task to administer set-shifting abilities and inhibition. Volume measurements and lesion–symptom mapping analyses were performed on postoperative MRI scans. Careful interpretation of the results shows a change in TMT performance and not on the Stroop Task when the lateral part of the arcuate fasciculus is damaged, indicating that disconnection of the lateral part of the dorsal stream might be correlated specifically with impaired set-shifting and not with inhibition. More importantly, this study underlines the need for international concertation to allow larger studies to increase power and perform more detailed analyses.

Unilateral Spatial Neglect

2014 ◽  
Author(s):  
Giuseppe Vallar ◽  
Nadia Bolognini
Keyword(s):  
Right Hemisphere ◽  
Parietal Lobe ◽  
The Body ◽  
Spatial Neglect ◽  
Motor Action ◽  
Unilateral Spatial Neglect ◽  
Semantic Level ◽  
The Right ◽  
Neglect Dyslexia ◽  
Contralesional Side

Left unilateral spatial neglect is the most frequent and disabling neuropsychological syndrome caused by lesions to the right hemisphere. Over 50% of right-brain-damaged patients show neglect, while right neglect after left-hemispheric damage is less frequent. Neglect patients are unable to orient towards the side contralateral to the lesion, to detect and report sensory events in that portion of space, as well as to explore it by motor action. Neglect is a multicomponent disorder, which may involve the contralesional side of the body or of extra-personal physical or imagined space, different sensory modalities, specific domains (e.g. ‘neglect dyslexia’), and worsen sensorimotor deficits. Neglect is due to higher-order unilateral deficits of spatial attention and representation, so that patients are not aware of contralesional events, which, however, undergo a substantial amount of unconscious processing up to the semantic level. Cross-modal sensory integration is also largely preserved. Neglect is primarily a spatially specific disorder of perceptual consciousness. The responsible lesions involve a network including the fronto-temporo-parietal cortex (particularly the posterior-inferior parietal lobe, at the temporo-parietal junction), their white matter connections, and some subcortical grey nuclei (thalamus, basal ganglia). Damage to primary sensory and motor regions is not associated to neglect. A variety of physiological lateralized and asymmetrical sensory stimulations (vestibular, optokinetic, prism adaptation, motor activation), and transcranial electrical and magnetic stimulations, may temporarily improve or worsen neglect. Different procedures have been successfully developed to rehabilitate neglect, using both ‘top down’ (training the voluntary orientation of attention) and ‘bottom up’ (the above-mentioned stimulations) approaches.

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