Familial occurrence of multiple intracranial aneurysms

1972 ◽  
Vol 37 (3) ◽  
pp. 364-367 ◽  
Author(s):  
Kazuhisa Nagae ◽  
Ikuo Goto ◽  
Kazuo Ueda ◽  
Yasuyuki Morotomi
Keyword(s):  
Histological Examination ◽  
Intracranial Aneurysms ◽  
Causative Factor ◽  
Internal Elastic Lamina ◽  
Content Type ◽  
Multiple Intracranial Aneurysms ◽  
The Brain ◽  
Elastic Lamina ◽  
Fine Print ◽  
Saccular Aneurysms

✓ A 48-year-old man and his 66-year-old mother had multiple intracranial saccular aneurysms visualized by angiography or verified at autopsy. Histological examination of the arteries at the base of the brain in the case autopsied showed a caterpillar tread-like appearance (“Raupenketten Elastica”) of the internal elastic lamina, which may indicate thinning of the elastic lamina and deserve consideration as a causative factor in the development of intracranial saccular aneurysms.

Prevalence of cerebral aneurysms in patients with persistent primitive trigeminal artery

1999 ◽  
Vol 90 (5) ◽  
pp. 865-867 ◽  
Author(s):  
Harry J. Cloft ◽  
Nasser Razack ◽  
David F. Kallmes
Keyword(s):  
Intracranial Aneurysms ◽  
Case Reports ◽  
Cerebral Aneurysms ◽  
Trigeminal Artery ◽  
Content Type ◽  
Persistent Primitive Trigeminal Artery ◽  
Unbiased Manner ◽  
Primitive Trigeminal Artery ◽  
Fine Print ◽  
Saccular Aneurysms

Object. The aim of this study was to determine the prevalence of cerebral saccular aneurysms in patients with persistent primitive trigeminal artery (PPTA). The prevalence of cerebral saccular aneurysms in patients with PPTA previously has been reported to be 14 to 32%, but this rate range is unreliable because it is based on collections of published case reports rather than a series of patients chosen in an unbiased manner.Methods. The authors retrospectively evaluated their own series of 34 patients with PPTA to determine the prevalence of cerebral aneurysms in this population. The prevalence of intracranial aneurysms in patients with PPTA was approximately 3% (95% confidence interval 0–9%).Conclusions. The prevalence of intracranial aneurysms in patients with PPTA is no greater than the prevalence of intracranial aneurysms in the general population.

Multiple intracranial aneurysms associated with moyamoya disease

1981 ◽  
Vol 54 (5) ◽  
pp. 673-676 ◽  
Author(s):  
Yoshihide Nagamine ◽  
Shinichiro Takahashi ◽  
Makoto Sonobe
Keyword(s):  
Moyamoya Disease ◽  
Intracranial Aneurysms ◽  
Operative Indication ◽  
Content Type ◽  
Multiple Intracranial Aneurysms ◽  
Vertebrobasilar System ◽  
Initial Symptoms ◽  
Fine Print

✓ A case of multiple intracranial aneurysms associated with unilateral moyamoya vessels is reported. The authors have reviewed the age, sex, initial symptoms, site of aneurysm, and operative indication in similar cases reported in the literature. It was found that aneurysms associated with moyamoya disease were frequently located in the vertebrobasilar system.

A physiological sealant for cerebrospinal fluid leaks

1977 ◽  
Vol 46 (2) ◽  
pp. 215-219 ◽  
Author(s):  
Gerald D. Silverberg ◽  
Christina B. Harbury ◽  
Edward Rubenstein
Keyword(s):  
Cerebrospinal Fluid ◽  
Histological Examination ◽  
Content Type ◽  
Cerebrospinal Fluid Leaks ◽  
The Brain ◽  
Fine Print ◽  
Csf Leaks

✓ A combination of concentrated platelets, thrombin, and fibrinogen was used to adhere a pericranial graft to surgically produced cerebrospinal fluid (CSF) fistulas in dogs. This sealant successfully stopped leakage of CSF in all fistulas produced in both acute and chronic preparations. All control animals leaked CSF acutely. In chronic control animals the CSF leaks sealed spontaneously but the grafts were not well incorporated. Histological examination of the grafts and underlying brain showed no injury to the brain or meningeal vessel from exposure to the platelet glue. Good fibrous union of the grafts to the dura was confirmed.

The size of intracranial saccular aneurysms

1970 ◽  
Vol 33 (4) ◽  
pp. 422-427 ◽  
Author(s):  
William F. McCormick ◽  
Gaston J. Acosta-Rua
Keyword(s):  
Intracranial Aneurysms ◽  
Autopsy Material ◽  
Autopsy Study ◽  
Content Type ◽  
Unruptured Aneurysms ◽  
Age And Sex ◽  
Fine Print ◽  
Saccular Aneurysms

✓ An autopsy study was made of the size of 191 saccular intracranial aneurysms (54 ruptured, 137 unruptured). Variations with age and sex, and ruptured and unruptured state were recorded and analyzed. Measurements on unfixed, unruptured aneurysms inflated by perfusion under 70 mm Hg pressure indicated that the size of aneurysms as generally determined in autopsy material is deceptively low.

Abnormal origin of bilateral ophthalmic arteries

1991 ◽  
Vol 74 (2) ◽  
pp. 287-289 ◽  
Author(s):  
Jun-ichiro Hamada ◽  
Isao Kitamura ◽  
Masahito Kurino ◽  
Nobuyuki Sueyoshi ◽  
Shozaburo Uemura ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Intracranial Aneurysms ◽  
Ophthalmic Artery ◽  
Internal Carotid ◽  
Content Type ◽  
Multiple Intracranial Aneurysms ◽  
Operative Findings ◽  
Ophthalmic Arteries ◽  
Fine Print

✓ The case of a 64-year-old woman with multiple intracranial aneurysms and abnormal ophthalmic arteries arising from the bifurcation of the internal carotid artery is described. It is believed that this type of anomaly of the ophthalmic artery has not previously been reported. The neuroradiological and operative findings of this case are presented.

Multiple intracranial aneurysms in sickle cell anemia

1985 ◽  
Vol 62 (3) ◽  
pp. 430-434 ◽  
Author(s):  
M. Chris Overby ◽  
Allen S. Rothman
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Intracranial Aneurysms ◽  
Neurological Complications ◽  
Review Of The Literature ◽  
Hemoglobin S ◽  
Content Type ◽  
Multiple Intracranial Aneurysms ◽  
Fine Print

✓ Neurological complications of sickle cell anemia occur in 18% to 29% of patients with homozygous hemoglobin S disease. A review of the literature yielded reports of two cases, both treated conservatively, of multiple intracranial aneurysms occurring in patients with sickle cell anemia. The authors report two cases of subarachnoid hemorrhage secondary to multiple intracranial aneurysms in patients with sickle cell anemia. One of the two patients underwent three craniotomies for ablation of six intracranial aneurysms. The techniques used in the treatment of these patients are presented.

Multiple intracranial aneurysms due to Coccidioides immitis infection

1987 ◽  
Vol 66 (3) ◽  
pp. 453-456 ◽  
Author(s):  
Mark N. Hadley ◽  
Neil A. Martin ◽  
Robert F. Spetzler ◽  
Peter C. Johnson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Young Woman ◽  
Intracranial Aneurysms ◽  
Mycotic Aneurysm ◽  
Coccidioides Immitis ◽  
Content Type ◽  
Multiple Intracranial Aneurysms ◽  
Fine Print

✓ True mycotic (fungal) aneurysms are distinctly uncommon. The case of a young woman with multiple intracranial aneurysms of Coccidioides immitis origin is presented. Coccidioides immitis organisms are not uncommon central nervous system pathogens and usually cause basilar meningitis and hydrocephalus. There are no previous reports of a coccidioidal mycotic aneurysm. The management of intracranial coccidioidomycosis and fungal aneurysms is reviewed.

Turbulence in human intracranial saccular aneurysms

1970 ◽  
Vol 33 (5) ◽  
pp. 485-497 ◽  
Author(s):  
Gary G. Ferguson
Keyword(s):  
Intracranial Aneurysms ◽  
Critical Reynolds Number ◽  
Vascular Tissue ◽  
Low Flow ◽  
Content Type ◽  
Structural Fatigue ◽  
Glass Model ◽  
The Mean ◽  
Fine Print ◽  
Saccular Aneurysms

✓ Preliminary experiments with glass model bifurcation aneurysms demonstrated that turbulent flow pattern occurs in the sac of an aneurysm at a low flow rate (critical Reynolds number, 400 ± 10 S.E.M.). A prediction that flow is turbulent in the sac of human intracranial saccular aneurysms was confirmed in a clinical study. Bruits, indicative of turbulence, were recorded with a phonocatheter from the sacs of 10 out of 17 intracranial aneurysms exposed at surgery where the mean arterial pressures were above 50 mm Hg. The amplitude of the bruits varied with the pressure. All of the patients in whom no bruit was found had profound Arfonad hypotension at the time of recording. Turbulence causes vibration in the wall of a vessel. This vibration produces and accelerates degenerative changes in vascular tissue by a process similar to the structural fatigue of metals by vibration. The author proposes that the turbulent blood flow within an aneurysm contributes to the degeneration of the elastica, and the production of the atheromatous changes, characteristically seen in its wall. This weakens the wall causing continuing enlargement and eventual rupture.

Cerebral aneurysms following radiotherapy for medulloblastoma

1989 ◽  
Vol 70 (4) ◽  
pp. 545-550 ◽  
Author(s):  
Peter J. Benson ◽  
Joo Ho Sung
Keyword(s):  
Cerebral Arteries ◽  
Cerebral Aneurysms ◽  
Content Type ◽  
Histological Features ◽  
Autopsy Examination ◽  
Cerebellar Medulloblastoma ◽  
Radiation Induced ◽  
The Brain ◽  
Fine Print ◽  
Saccular Aneurysms

✓ Three patients, two males and one female aged 21, 14, and 31 years, respectively, developed cerebral saccular aneurysms several years after undergoing radiotherapy for cerebellar medulloblastoma at 2, 5, and 14 years of age, respectively. Following surgery, all three received combined cobalt-60 irradiation and intrathecal colloidal radioactive gold (198Au) therapy, and died from rupture of the aneurysm 19, 9, and 17 years after the radiotherapy, respectively. Autopsy examination revealed no recurrence of the medulloblastoma, but widespread radiation-induced vasculopathy was found at the base of the brain and in the spinal cord, and saccular aneurysms arose from the posterior cerebral arteries at the basal cistern or choroidal fissure. The aneurysms differed from the ordinary saccular aneurysms of congenital type in their location and histological features. Their locations corresponded to the areas where intrathecally administered colloidal 198Au is likely to pool, and they originated directly from a segment of the artery rather than from a branching site as in congenital saccular aneurysms. It is, therefore, concluded that the aneurysms in these three patients were most likely radiation-induced.

Giant fusiform aneurysms in the middle cerebral artery presenting with hemorrhages of different origins

2003 ◽  
Vol 99 (2) ◽  
pp. 391-396 ◽  
Author(s):  
Nobutaka Horie ◽  
Nobuaki Takahashi ◽  
Shoji Furuichi ◽  
Katsuharu Mori ◽  
Masanari Onizuka ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Strong Relationship ◽  
Internal Elastic Lamina ◽  
Content Type ◽  
Appropriate Therapy ◽  
Different Origins ◽  
Intramural Hemorrhage ◽  
Elastic Lamina ◽  
Fine Print

✓ Three cases of giant fusiform aneurysms in the middle cerebral artery (MCA) presenting with hemorrhages of different origins are reported, and appropriate literature is reviewed to investigate the characteristics of these lesions. Two patients had suffered a subarachnoid hemorrhage and the other had an intramural hemorrhage (dissection). Pathologically, these aneurysms presented with hemorrhages of different origins; classic rupture type (Case 1), dissection type (Case 2), and atherosclerosis-related thrombosis type (Case 3). Based on surgical and pathological investigations in these three cases and a review of the reported literature, the authors propose that giant fusiform aneurysms in the MCA are characterized by weaknesses in the internal elastic lamina with intimal thickening. Therefore, these lesions have the potential to present with hemorrhage in each of the three types. This finding indicates that there is a strong relationship between the pathological features of giant fusiform aneurysms and their clinical course, and that it is necessary to determine appropriate therapy for giant fusiform aneurysms in the MCA by evaluating cerebral blood flow, even if the lesions are found incidentally.

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