Hemangiopericytoma-like synovial sarcoma of the lumbar spine

2006 ◽  
Vol 4 (2) ◽  
pp. 179-182 ◽  
Author(s):  
Nikolaos Sakellaridis ◽  
Helen Mahera ◽  
Spiros Pomonis
Keyword(s):  
Differential Diagnosis ◽  
Cervical Spine ◽  
Lumbar Spine ◽  
Synovial Sarcoma ◽  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor ◽  
Deep Soft Tissue ◽  
Pathological Characteristics ◽  
The Brain

✓The purpose of this report is to demonstrate that synovial sarcoma should be included in the differential diagnosis of tumors originating from the lumbar spine, especially if they show hemangiopericytoma-like pathological characteristics. A synovial sarcoma is a mesenchymal spindle cell tumor that displays variable epithelial differentiation including glandular formation. It is unrelated to a synovium. More than 80% of these lesions arise in the deep soft tissue of the extremities. The tumor frequently arises adjacent to joints or tendon sheaths. The authors describe a young woman with a hemangiopericytoma-like tumor of the lumbar spine. During repeated operation, this lesion was shown to be a synovial sarcoma, which had invaded the dura mater. The tumor metastasized to the mediastinum and the intradural cervical spine and, finally, to the brain and the lungs. To the authors’ knowledge, this is the first reported case of a synovial sarcoma originating from the lumbar spine.

scholarly journals Myofibroblastoma of the Breast: Literature Review and Case Report

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Mario Metry ◽  
Mohamad Shaaban ◽  
Magdi Youssef ◽  
Michael Carr
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Literature Review ◽  
Spindle Cell ◽  
Cell Tumor ◽  
Breast Mass ◽  
Rare Tumor ◽  
Spindle Cell Tumor ◽  
Pathological Features

Myofibroblastoma of the breast is a rare benign spindle cell tumor. The main aim of this study is to review the literature of this rare tumor. We present a case of a mammary myofibroblastoma occurring in an 82-year-old man, emphasizing the clinical, radiological, and pathological features. The tumor was successfully identified and managed in our hospital. We would like to draw the attention of clinicians to myofibroblastoma as a rare possibility in the differential diagnosis of a breast mass.

Laparoscopic Liver Resection of a Desmoplastic Nested Spindle Cell Tumor of the Liver

2010 ◽  
Vol 76 (9) ◽  
pp. 184-185
Author(s):  
Caridad Marín ◽  
Ricardo Robles ◽  
Matilde Fuster ◽  
Pascual Parrilla
Keyword(s):  
Liver Resection ◽  
Laparoscopic Liver Resection ◽  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor

Hyalinizing spindle cell tumor with giant rosettes of the omentum

2003 ◽  
Vol 29 (6) ◽  
pp. 388-391 ◽  
Author(s):  
Asako Koishi ◽  
Hideto Gomibuchi ◽  
Jun Inoue ◽  
Shigeki Minoura ◽  
Eisaku Itoh ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor

scholarly journals Malignant Spindle Cell Tumor Breast—a Diagnostic Dilemma

2018 ◽  
Vol 9 (3) ◽  
pp. 387-390 ◽  
Author(s):  
Sheetal Arora ◽  
Deepshikha Rana ◽  
Mukta Pujani ◽  
Varsha Chauhan
Keyword(s):  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor ◽  
Diagnostic Dilemma

Primary ovarian synovial sarcoma

2021 ◽  
Vol 14 (11) ◽  
pp. e244756
Author(s):  
Muhammad Amin ur Rahman ◽  
Khalid Al Wadi ◽  
Al Nuqaydan ◽  
Raghad Tallab
Keyword(s):  
Differential Diagnosis ◽  
Synovial Sarcoma ◽  
Molecular Pathology ◽  
Genital Tract ◽  
Spindle Cell ◽  
Female Genital Tract ◽  
Rare Occurrence ◽  
Spindle Cell Tumours ◽  
Spindle Cell Tumour ◽  
Female Genital

Synovial sarcoma (SS) has a rare occurrence in the female genital tract. Only three prior reports of primary ovarian sarcoma could be retrieved after a thorough literature review. We are reporting a case of primary ovarian SS in a young woman. The tumour showed monophasic spindle cell morphology, and there was a wide list of differential diagnosis to consider. We confirmed the diagnosis by cytogenetics Flourescent Insitu Hybridisation (FISH) technique to identify the classical translocation. The diagnosis of this disease can be challenging especially if the tumour is of monophasic type. Morphology and immunohistochemistry are not enough to confirm the diagnosis in many cases. A confirmatory molecular pathology test is paramount. We have discussed the differential diagnosis of spindle cell tumours in ovary. We suggest that SS should be in the differential diagnoses when facing any atypical spindle cell tumour in the ovary. Molecular pathology techniques can help to confirm the diagnosis.

Hyalinizing Spindle Cell Tumor With Giant Rosettes—A Soft Tissue Tumor With Mesenchymal and Neuroendocrine Features

2000 ◽  
Vol 124 (8) ◽  
pp. 1179-1184 ◽  
Author(s):  
Pablo A. Bejarano ◽  
Tapan A. Padhya ◽  
Roger Smith ◽  
Ruthann Blough ◽  
James J. Devitt ◽  
...  
Keyword(s):  
Soft Tissues ◽  
Spindle Cell ◽  
S100 Protein ◽  
Neuron Specific Enolase ◽  
Neuroendocrine Differentiation ◽  
Cell Tumor ◽  
Factor Xiiia ◽  
Spindle Cell Tumor ◽  
Balanced Translocation ◽  
Spindle Cell Proliferation

Abstract Context.—Hyalinizing spindle cell tumor with giant rosettes is a recently described biphasic neoplasm of soft tissues that shares mesenchymal and neuroendocrine features. Its morphologic structure is distinctive, with the presence of hyalinized paucicellular foci that are termed rosettes. The cells around the latter display positive immunoreactivity for neuroendocrine markers. The small number of cases described to date indicates that they tend to be localized in the extremities. Objective.—To describe the clinicopathologic features of 2 unusual cases of hyalinizing spindle cell tumor with giant rosettes. Methods and Results.—One tumor was located in the prestyloid parapharyngeal space and the second in the left thigh. Both tumors were well circumscribed and surrounded by a thin capsulelike fibrous band without infiltrating projections. The rosettes were embedded in a spindle cell proliferation. Immunohistochemical stains showed positive results for S100 protein, synaptophysin, CD57, protein gene product 9.5, and neuron-specific enolase exclusively in the cells palisading the rosettes. These markers were negative in the spindle cell portions of the tumor. The latter were immunoreactive for factor XIIIa, vimentin, HAM56, collagen IV, and CD68. Vimentin was the only marker shared by the rosette-forming cells and the spindle cells. Ultrastructurally, the rosette-forming cells contained neurosecretory granules. This study describes the first cytogenetic analysis in this type of tumor revealing 2 cell lines, both containing a balanced translocation between chromosomes 7 and 16. Follow-up of the patients at 16 and 8 months did not disclose evidence of recurrence. Conclusions.—These 2 new cases increase the awareness of hyalinizing spindle cell tumor with giant rosettes and demonstrate that it is a spindle cell neoplasm of unique cytogenetic rearrangements composed of dendritic, histiocytic, and fibroblastic cells admixed with cells that have neuroendocrine differentiation.

S100 and CD34 positive spindle cell tumor with prominent perivascular hyalinization and a novel NCOA4‐RET fusion

2019 ◽  
Author(s):  
Michael Michal ◽  
Nikola Ptáková ◽  
Petr Martínek ◽  
Zoran Gatalica ◽  
Dmitry V. Kazakov ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor

scholarly journals A Rare Primary intramuscular hydatid cyst misdiagnosed as malignant spindle cell tumor: A Case Report

2016 ◽  
Vol 15 (4) ◽  
pp. 628-630
Author(s):  
Ankitbhai Atulbhai Shah ◽  
Naveed Shah ◽  
Hiral Ankitbhai Shah ◽  
Ghanish Panjwani ◽  
BB Pandey
Keyword(s):  
Hydatid Cyst ◽  
Hydatid Disease ◽  
Musculoskeletal System ◽  
Spindle Cell ◽  
Medical Science ◽  
Cell Tumor ◽  
Spindle Cell Tumor ◽  
En Bloc ◽  
Systemic Dissemination ◽  
Careful Management

Primary hydatid disease of musculoskeletal system is rare. A 46 year old man presented with soft swelling in anterior aspect of thigh of two years duration which was gradually increasing in size. He was initially diagnosed as malignant spindle cell tumor of thigh, but ultrasonography and Commuted Tomography Scan revealed to be a cystic swelling suggestive of hydatid disease. Our patient had not been operated for hydatid disease previously and investigations did not reveal any hydatid cyst in liver, lung or spleen. So our patient was diagnosed having primary hydatid disease of musculoskeletal system. Serologic test (ELISA) was negative. Patient was given albendazole preoperatively. A careful management is required to prevent systemic dissemination and anaphylactic shock. The swelling was removed en bloc without causing damage to cyst wall and advised for adjunctive albendazole chemotherapy (15 mg/kg/day) for three months.Bangladesh Journal of Medical Science Vol.15(4) 2016 p.628-630

Functional islet cell carcinoma metastasizing as spindle cell tumor

1961 ◽  
Vol 30 (4) ◽  
pp. 619-623 ◽  
Author(s):  
Robert S. Karsh ◽  
Harold Freedman ◽  
Herman T. Blumenthal
Keyword(s):  
Cell Carcinoma ◽  
Islet Cell ◽  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor ◽  
Islet Cell Carcinoma

Low-Grade Fibromyxoid Sarcoma and Hyalinizing Spindle Cell Tumor With Giant Rosettes Share a Common t(7;16)(q34;p11) Translocation

2003 ◽  
Vol 27 (9) ◽  
pp. 1229-1236 ◽  
Author(s):  
Robin Reid ◽  
M. V. Chandu de Silva ◽  
Lindsay Paterson ◽  
Eleanor Ryan ◽  
Cyril Fisher
Keyword(s):  
Spindle Cell ◽  
Cell Tumor ◽  
Low Grade ◽  
Spindle Cell Tumor ◽  
Fibromyxoid Sarcoma
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