Contrast Enhancement of Intracranial Aneurysms on 3T 3D Black-Blood MRI and Its Relationship to Aneurysm Recurrence following Endovascular Treatment

Black blood magnetic resonance imaging (MRI)is a promising imaging tool in predicting aneurysm rupture. Could it be also valuable in evaluating the treatment effect of endovascular and conservative treated aneurysms? Two patients were treated with stent and coil and one with Aspirine (ASS). Correlation of treatment response and contrast enhancement of the aneurysm wall is examined. In the first case stenting failed to treat the aneurysm and contrast enhancement in the wall did never subside during follow up black blood MRI. In the second case the aneurysm responded well to stenting and decreased in size, which was correlating significantly with attenuation of contrast enhancement in black blood MRI. In the third case the aneurysm responded to ASS treatment by decreasing in size as shown in follow up MR-angiography and the contrast enhancement in its wall decreased after 8 months of therapy. Black blood MRI seems to be a promising tool not only in predicting aneurysms at risk of rupture, but also in observing treatment responses after endovascular procedures or even Aspirine administration. When contrast enhancement decreases, aneurysm treatment seems to be successful as can be shown in decreasing size in the follow up angiography.

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Faculty Opinions recommendation of Use of contrast enhancement and high-resolution 3D black-blood MRI to identify inflammation in atherosclerosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.7605957.7908055 ◽

2011 ◽

Author(s):

Arthur Stillman ◽

Chesnal Arepalli

Keyword(s):

High Resolution ◽

Contrast Enhancement ◽

Black Blood ◽

Black Blood Mri

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Use of Contrast Enhancement and High-Resolution 3D Black-Blood MRI to Identify Inflammation in Atherosclerosis

JACC Cardiovascular Imaging ◽

10.1016/j.jcmg.2010.08.012 ◽

2010 ◽

Vol 3 (11) ◽

pp. 1127-1135 ◽

Cited By ~ 13

Author(s):

Jin Hur ◽

Jaeseok Park ◽

Young Jin Kim ◽

Hye-Jeong Lee ◽

Hyo Sup Shim ◽

...

Keyword(s):

High Resolution ◽

Contrast Enhancement ◽

Black Blood ◽

Black Blood Mri

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Contrast enhancement of vascular walls of intracranial high flow malformations in black blood MRI indicates high inflammatory activity

Chinese Neurosurgical Journal ◽

10.1186/s41016-018-0120-0 ◽

2018 ◽

Vol 4 (1) ◽

Author(s):

Athanasios K. Petridis ◽

Maxine Dibue-Adjei ◽

Jan F. Cornelius ◽

Marian Preetham Suresh ◽

Lan Li ◽

...

Keyword(s):

Contrast Enhancement ◽

High Flow ◽

Inflammatory Activity ◽

Black Blood ◽

Vascular Walls ◽

Black Blood Mri

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Aneurysm wall enhancement in black blood MRI correlates with aneurysm size. Black blood MRI could serve as an objective criterion of aneurysm stability in near future

Clinics and Practice ◽

10.4081/cp.2018.1089 ◽

2018 ◽

Author(s):

Athanasios K. Petridis ◽

Andreas Filis ◽

Elias Chasoglou ◽

Igor Fischer ◽

Maxine Dibué-Adjei ◽

...

Keyword(s):

Contrast Enhancement ◽

Scoring Systems ◽

Aneurysm Rupture ◽

Width Ratio ◽

Anatomical Location ◽

Black Blood ◽

Objective Criterion ◽

Aneurysm Wall ◽

Black Blood Mri ◽

Clinical Scoring

The increasing number of incidental intracranial aneurysms creates a dilemma of which aneurysms to treat and which to observe. Clinical scoring systems consider risk factors for aneurysm rupture however objective parameters for assessment of aneurysms stability are needed. We retrospectively analysed contrast enhancing behaviour of un-ruptured aneurysms in the black blood magnetic resonance imaging (MRI) in N=71 patients with 90 aneurysms and assessed correlation between aneurysm wall contrast enhancement (AWCE) and aneurysm anatomy and clinical scoring systems. AWCE is associated with aneurysm height and height to width ratio in ICA aneurysms. AWCE is correlated to larger aneurysms in every anatomical location evaluated. However the mean size of the contrast enhancing aneurysms is significantly different between anatomical localizations indicating separate analyses for every artery. Clinical scoring systems like PHASES and UIATS correlate positively with AWCE in black blood MRI. MRI aneurysm wall contrast enhancement is a positive predictor for aneurysm instability and should be routinely assessed in follow up of incidental aneurysms. Aneurysms smaller than 7 mm with AWCE should be followed closely with focus on growth, as they may be prone to growth and rupture.

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Pseudo‐Enhancement in Intracranial Aneurysms on Black‐Blood MRI : Effects of Flow Rate, Spatial Resolution, and Additional Flow Suppression

Journal of Magnetic Resonance Imaging ◽

10.1002/jmri.27587 ◽

2021 ◽

Author(s):

Mariya S. Pravdivtseva ◽

Franziska Gaidzik ◽

Philipp Berg ◽

Carson Hoffman ◽

Leonardo A. Rivera‐Rivera ◽

...

Keyword(s):

Spatial Resolution ◽

Flow Rate ◽

Intracranial Aneurysms ◽

Black Blood ◽

Black Blood Mri

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Wall enhancement segmentation for intracranial aneurysm

Current Directions in Biomedical Engineering ◽

10.1515/cdbme-2020-0045 ◽

2020 ◽

Vol 6 (1) ◽

Author(s):

Annika Niemann ◽

Naomi Larsen ◽

Bernhard Preim ◽

Sylvia Saalfeld

Keyword(s):

Intracranial Aneurysm ◽

Intracranial Aneurysms ◽

Automatic Segmentation ◽

Black Blood ◽

Manual Segmentation ◽

Lower Intensity ◽

Black Blood Mri

AbstractWe present a tool for automatic segmentation of wall enhancement of intracranial aneurysms in black blood MRI. The results of the automatic segmentation with several configurations is compared to manual expert segmentations. While the manual segmentation includes some voxels of lower intensity not present in the automatic segmentation, overall the volume of the automatic segmentation is higher.

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