scholarly journals Unique Application of K-Y Jelly in Cryotherapy for Giant Cell Tumors of the Distal Femur - A Case Report

GCTs are a locally aggressive tumor that can result in significant pain and dysfunction through the disruption of bony and nearby soft tissue architecture. Although generally benign, these tumors have been shown to have 1-9% chance of metastasis and a local recurrence rate of up to 65%. For these reasons, appropriate treatment is essential to remove primary lesions as well as reduce the odds of metastatic disease and lower recurrence rates. Cryosurgery is a welldescribed technique used to achieve local control of primary GCTs. Modern cryoablation utilizes a cryoprobe to freeze surrounding tissues via release of a thermal conducting gas (argonhelium). The optimal technique for eradication of GCT is a widely debated topic rooted in rates of complications and tumor recurrence. Herein, we describe a case report of a 30-year-old female with a large distal femoral GCT that underwent intralesional curettage and adjunctive cryotherapy utilizing K-Y jelly as a semi-solid medium to transmit the freeze zone more evenly within the cavity. Following cryoablation, the cavity was filled with antibiotic loaded polymethyl methacrylate cement. This technique has scarcely been described in the literature and warrants further investigation.


Hand ◽  
2020 ◽  
pp. 155894472092292
Author(s):  
Kai-Lou C. Yue ◽  
Jonathan Lans ◽  
René M. Castelein ◽  
David I. Suster ◽  
G. Petur Nielsen ◽  
...  

Background: Benign tumors of the hand present in a wide array of histological subtypes and compose most of the bony tissue tumors in the hand. This study evaluates the characteristics and treatment of benign bone tumors in light of one institution’s experience. Methods: Histologically confirmed benign tumors of the hand were retrospectively identified using International Classification of Diseases codes from 1992 to 2015. A medical chart review was conducted to collect patient characteristics and tumor epidemiology and treatment. Results: A total of 155 benign bone tumors were identified. The median age of patients at the time of surgery was 39.9 ± 12.8 years. All bone tumors were located in the digits, and most were treated by intralesional curettage (n = 118, 76%). Pathologic fractures occurred in 79 bone tumors (51%). Conclusion: Enchondromas (n = 118, 76%) were the most common bone tumor in this series, whereas giant cell tumors were the most destructive and also had the highest recurrence rate (40%). Awareness of tumor features may help physicians with diagnosis, and awareness of recurrence rates is important when counseling patients.



Nowa Medycyna ◽  
2018 ◽  
Vol 25 (2) ◽  
Author(s):  
Justyna Koszarska-Mirek ◽  
Jakub Orleański

Fibromatosis (desmoid, desmoid tumour) is a tumour belonging to the group of fibrous tissue proliferative diseases. Although the tumour cannot produce distant metastases, it shows local malignancy by invading adjacent tissues, as well as high recurrence rates after local resection. The incidence of fibromatosis is 2-4 cases per 1 million inhabitants per year. Three types of fibromatosis have been distinguished: extra-abdominal, abdominal wall and intra-abdominal type. Although the most common types are sporadic, coexistence with familial adenomatous polyposis (FAP), known as the Gardner’s syndrome, is observed. Available therapeutic options include surgical treatment, watchful waiting, hormone therapy, non-steroid anti-inflammatory drugs, chemotherapy and radiation therapy. This case report aims to draw attention to the difficulties in selecting an appropriate treatment option, limited surgical treatment, the psychological aspect of the disease, as well as the need to actively search for modern diagnostic and therapeutic solutions. We present a case of a 26-year-old patient who was ultimately diagnosed with a desmoid tumour invading the abdominal wall and internal abdominal organs. The patient presented to a county hospital due to suspected gastrointestinal obstruction. It was found from medical history that the patient had palpated a tumour of the abdominal wall 9 months before admission.



2021 ◽  
Vol 11 (1) ◽  
Author(s):  
A Vinoth ◽  
D Bharani Kumar ◽  
S Manivannan

Introduction: Chondroblastoma is a rare benign cartilaginous neoplasm arising in the epiphysis of long bones in young patients. It is an uncommon benign but locally aggressive tumor, mostly located in the secondary centers of ossification. These tumors arise near a joint or growth plate and surgical excision is always challenging. Case Report: A 13-year-old boy presented with intermittent knee pain, swelling, and limitation of movements for 1 year. On examination, magnetic resonance imaging revealed a hyperintense lesion in distal femoral epiphysis with superior transphyseal extension and inferior thinning of cortex with cartilage breach. Histopathological examination confirmed the diagnosis of chondroblastoma of distal femur. We report a novel technique of approach in a case of distal femoral chondroblastoma in a skeletally immature individual. Conclusion: The technique we incorporated had an adequate exposure to reach the lesion for a complete curettage and bone grafting. It also reduced further injury to cartilage and physeal plate. Keywords: Chondroblastoma, cartilage breach, curettage, bone grafting.



2021 ◽  
pp. 131-137
Author(s):  
Santanu Kar ◽  
Hemant Bansal ◽  
Vijay Sharma ◽  
Kamran Farooque

Fractures of the supracondylar and intercondylar region of the distal femur usually result from high velocity injury that is uncommonly associated with violation of the integrity of the extensor mechanism. The consequences of missed quadriceps injury associated with a distal femur fracture are devastating. The present case report illustrates the importance of recognizing the rare association of quadriceps tear with distal femoral fractures, an appropriate surgical approach to repair the tear as well as fixation of fracture, and a protocol of postoperative rehabilitation to achieve a successful outcome.



2015 ◽  
Vol 22 (1) ◽  
pp. 112-116
Author(s):  
Amit Agrawal ◽  
Vissa Shanthi ◽  
Baddukonda Appala Ramakrishna ◽  
Kuppili Venkata Murali Mohan

Abstract First characterized by Stroebe, the gliosarcomas are highly malignant and rare primary tumor of the brain composed of neoplastic glial cells in association with spindle cell sarcomatous elements (biphasic tissue patterns). In spite of being recognized as two different pathologies studies have not shown any significant differences between gliosarcoma and glioblastoma with regard to age, sex, size, clinical presentation, and median survival. In summary, gliosarcoma is an aggressive tumor with a propensity to recur and re-grow with poor outcome. Future studies are needed to understand the true pathology of these biphasic tumors.



2010 ◽  
Vol 2010 ◽  
pp. 1-3
Author(s):  
Daichi Ishimaru ◽  
Takatoshi Ohno ◽  
Masato Maeda ◽  
Yutaka Nishimoto ◽  
Katsuji Shimizu

Treatment with a combination of chemotherapy and radiotherapy is known to be associated with oesophageal stricture in both children and adults with malignancies. However, oesophageal stricture resulting from chemotherapy alone is a rare complication, with few reports on it. We experienced a rare paediatric case of oesophageal stricture caused by chemotherapy for osteosarcoma of the left distal femur. After completion of the chemotherapy course, the patient showed dysphagia caused by the oesophageal stricture and underwent balloon dilatation for the oesophageal stricture. After balloon dilatation, he was able to ingest solid foods, and the oesophagus was normal without any strictures at the last follow-up (20 months after ballooning). Therefore, oesophageal stricture should be considered as a complication of treatment with chemotherapy alone in children with malignancies.



Injury ◽  
2018 ◽  
Author(s):  
M. Cavanna ◽  
V. Peschiera ◽  
L. Staletti ◽  
M. Berlusconi


2009 ◽  
Vol 66 (4) ◽  
pp. 333-337 ◽  
Author(s):  
Danica Cvetkovic-Matic ◽  
Milika Asanin ◽  
Dragan Matic ◽  
Branislava Ivanovic ◽  
Dragan Simic ◽  
...  

Background. The occurrence of an acute myocardial infarction following a hornet sting has been very rarely reported in the previous literature. Pathogenetic mechanisms include direct action of the venom components on the coronary endothelium and allergic reaction with mediators released from mast cells. The anaphylactic reaction and venom components can produce acute coronary artery thrombosis. Case report. We reported a 45-year-old man with acute myocardial infarction after a hornet sting in the presence of anaphylaxis. We also discussed clinical implications and pathophysiological mechanisms of acute myocardial infarction caused by hymenoptera sting. Conclusion. A case report of this unusual acute myocardial infarction highlights the potential acute myocardial ischemia associated with hymenoptera sting which requests early diagnosis, thorough cardiovascular evaluation and appropriate treatment.



2016 ◽  
Vol Volume 9 ◽  
pp. 859-863 ◽  
Author(s):  
Mingxing Lei ◽  
Yaosheng Liu ◽  
Shaoxing Yang ◽  
Weigang Jiang ◽  
Yuncen Cao ◽  
...  


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Daniel Kirkpatrick ◽  
Tyler Smith ◽  
Mitchell Kerfeld ◽  
Taylor Ramsdell ◽  
Hasnain Sadiq ◽  
...  

With less than 1% of patients who use benzodiazepines being affected, paradoxical responses to benzodiazepines are rare. In this case report, we outline the course of an 80-year-old female who developed a paradoxical response to benzodiazepines. Significant medical and psychiatric history includes anxiety, mood disorder, hypothyroidism, bilateral mastectomy, goiter removal, and triple bypass. The patient presented with mental status changes, anxiety, motor restlessness, and paranoia. Over time, a temporal relationship between the severity of the patient’s motor agitation and intake of alprazolam was observed. As doses of alprazolam were decreased, her motor agitation became less severe. In addition to motor agitation, the patient also demonstrated increased aggressiveness, a subjective feeling of restlessness, and increased talkativeness. As her dose of alprazolam decreased, many of the patient’s symptoms were observed to decrease. This case report also discusses theories regarding the pathophysiology of paradoxical reactions to benzodiazepines, known risk factors, and appropriate treatment.



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