scholarly journals Glipizide Loaded Gastro Retentive Floating Tablets: Formulation and in vitro Evaluation

2019 ◽  
Vol 2 (1) ◽  
Keyword(s):  
In Vitro Evaluation ◽  
Floating Tablets ◽  
Gastro Retentive

FORMULATION DEVELOPMENT AND IN VITRO EVALUATION OF FLOATING TABLETS OF LAFUTIDINE BY EMPLOYING EFFERVESCENT TECHNOLOGY

2017 ◽  
Vol 5 (2) ◽  
pp. 26-44
Author(s):  
Vageesh N.M ◽  
◽  
Sri Sura Ramya ◽  
Begum K Gulijar ◽  
Swathi B ◽  
...  
Keyword(s):  
Formulation Development ◽  
In Vitro Evaluation ◽  
Floating Tablets

Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Di Chen ◽  
Xiang-Yu Xu ◽  
Rui Li ◽  
Gen-Ao Zang ◽  
Yue Zhang ◽  
...  
Keyword(s):  
In Vitro Evaluation ◽  
Floating Tablets ◽  
3D Printed

Formulation and Evaluation of Gastro-Retentive Floating Extended Release Metoprolol Tablets using Sodium Alginate and HPMC K-100M Combination

2015 ◽  
Vol 8 (3) ◽  
pp. 2947-2954
Author(s):  
Ashok Thulluru ◽  
M. Mohan Varma ◽  
C M Setty ◽  
Pavan Kumar Chintamaneni ◽  
S. Sriharsha Vardhan
Keyword(s):  
Drug Release ◽  
Sodium Alginate ◽  
Fickian Diffusion ◽  
Wet Granulation ◽  
Average Weight ◽  
Metoprolol Succinate ◽  
Floating Tablets ◽  
Zero Order Kinetics ◽  
Gastro Retentive

The present study was aimed to convert Metoprolol Succinate convert into Gastro Retentive Floating Tablet (GRFT). The gas generating floating tablets of Metoprolol Succinate were prepared to increase the gastric retention and to extend the drug release up to 12 hr. and thereby enhancing its bioavailability. The floating tablets were formulated using HPMCK 100M alone and with the combination of sodium alginate to the polymer of varying concentrations. The tablets were prepared by non-aqueous wet granulation method. The formulated granules were evaluated for pre-compression studies, after the compression of tablets they were subjected to various post-compression studies: Average weight, thickness, density, hardness, % friability, % drug content, (In vitro buoyancy studies: floating time, total floating time and matrix integrity up to 12 hr) and the In vitro drug release studies. The optimized formulation (F4) was found to follow a near perfect zero order kinetics (regression coefficient,      r2 = 0.978). Higuchi plot for formulation, F4, showed r2 value of 0.978, suggesting that the diffusion and erosion plays an important role in the controlled release of the drug. The data was fitted to the Korsemeyer-Peppa’s equation; and the value of the diffusion component (n=0.654), for the formulation F4, indicated that the drug release follows non-Fickian diffusion.  

Formulation and in-vitro Evaluation of Theophylline Floating Tablets

2021 ◽  
pp. 128-141
Author(s):  
E. I. Akpabio ◽  
D. E. Effiong ◽  
T. O. Uwah ◽  
G. Jacob
Keyword(s):  
In Vitro Evaluation ◽  
Floating Tablets

In vitro Evaluation of Gastro Retentive Drug Delivery System of Lansoprazole

2019 ◽  
Vol 12 (8) ◽  
pp. 3649
Author(s):  
Veeranagoud Biradar ◽  
Jeevan Matada Basavarajaiah ◽  
Myat Thu Thu Win ◽  
Leneena Gudugunta ◽  
KV Suresh ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
In Vitro Evaluation ◽  
Gastro Retentive
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