The effects of amines on oxidative homo-coupling of terminal alkynes promoted by copper salts
2005 ◽
Vol 2005
(2)
◽
pp. 112-115
◽
Keyword(s):
The effects of all kinds of amines on homo-couplings (Glaser reactions) of terminal alkynes promoted by copper salts and the Sonogashira coupling reactions were studied systematically. Diethylamine (2° amine) can serve as an excellent solvent, base and coordination ligand in the oxidative homo-coupling of terminal alkynes and several modified Glaser coupling procedures have been developed which are based on a catalytic amount of cuprous salts (CuI, CuBr or CuCl) with diethylamine systems. Homo-coupling of terminal acetylenes in the Sonogashira reaction could be inhibited by using triethylamine (3° amine) as reaction medium, and the cross-coupling products were formed as the exclusive products.
2019 ◽
Vol 15
◽
pp. 2907-2913
◽
Keyword(s):
2021 ◽
Vol 43
(1)
◽
pp. 95-95
Keyword(s):
2018 ◽
Vol 14
◽
pp. 1871-1884
◽
Keyword(s):
2010 ◽
Vol 132
(12)
◽
pp. 4101-4103
◽
Keyword(s):
Keyword(s):