Expression of inducible nitric oxide synthase (iNOS) in oral precancer and oral squamous cell carcinoma: An immunohistochemical study

2011 ◽  
Vol 8 (3) ◽  
pp. 155-160 ◽  
Author(s):  
Soma Susan Varghese ◽  
P.M. Sunil ◽  
R. Nirmal Madhavan
Keyword(s):  
Nitric Oxide ◽  
Squamous Cell Carcinoma ◽  
Nitric Oxide Synthase ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Inducible Nitric Oxide Synthase ◽  
Squamous Cell ◽  
Immunohistochemical Study ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

The importance of inducible nitric oxide synthase and nitrotyrosine as prognostic markers for oral squamous cell carcinoma

2019 ◽  
Vol 48 (10) ◽  
pp. 967-975 ◽  
Author(s):  
João Paulo Silva Servato ◽  
Carlos Ueira Vieira ◽  
Paulo Rogério de Faria ◽  
Sérgio Vitorino Cardoso ◽  
Adriano Mota Loyola
Keyword(s):  
Nitric Oxide ◽  
Squamous Cell Carcinoma ◽  
Nitric Oxide Synthase ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Inducible Nitric Oxide Synthase ◽  
Squamous Cell ◽  
Prognostic Markers ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

Association between Inducible Nitric Oxide Synthase Expression and p53 Status in Human Esophageal Squamous Cell Carcinoma

Oncology ◽  
2002 ◽  
Vol 64 (1) ◽  
pp. 90-96 ◽  
Author(s):  
Manabu Matsumoto ◽  
Mutsuo Furihata ◽  
Atsushi Kurabayashi ◽  
Keijiro Araki ◽  
Shiro Sasaguri ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Squamous Cell Carcinoma ◽  
Nitric Oxide Synthase ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Inducible Nitric Oxide Synthase ◽  
Squamous Cell ◽  
P53 Status ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

Third Place — Resident Basic Science Award 1995: Immunohistochemical Characterization of Nitric Oxide Synthase Activity in Squamous Cell Carcinoma of the Head and Neck

1995 ◽  
Vol 113 (5) ◽  
pp. 541-549
Author(s):  
Kristina W. Rosbe ◽  
Jiri Prazma ◽  
Peter Petrusz ◽  
Whit Mims ◽  
Steve S. Ball ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Squamous Cell Carcinoma ◽  
Nitric Oxide Synthase ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Inducible Nitric Oxide Synthase ◽  
Squamous Cell ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity ◽  
Inducible Nitric Oxide

This study was designed to investigate the presence of nitric oxide in human squamous cell carcinoma of the head and neck. We localized the activity of nitric oxide synthase in these tumors through immunohistochemical analysis using antibodies to L-citrulline (a byproduct of nitric oxide synthase), to inducible nitric oxide synthase, and to constitutive nitric oxide synthase. We found presence of inducible enzyme in squamous cells throughout these tumors, with the highest intensity staining occurring directly around keratin pearls. Our findings suggest that inducible nitric oxide synthase activity is present in squamous cell carcinomas of the head and neck, leading us to conclude that inducible nitric oxide synthase may play a significant role in tumor growth.

Sign in / Sign up

Export Citation Format

Share Document