Classification of Invasive Ductal Carcinoma from histopathology breast cancer images using Stacked Generalized Ensemble

2020 ◽  
pp. 1-16
Author(s):  
Deepika Kumar ◽  
Usha Batra
Keyword(s):  
Breast Cancer ◽  
Machine Learning ◽  
Deep Learning ◽  
Invasive Ductal Carcinoma ◽  
Cancer Detection ◽  
Ductal Carcinoma ◽  
Machine Learning Algorithms ◽  
Diagnostic Methods ◽  
Learner Model ◽  
Histopathological Images

Breast cancer positions as the most well-known threat and the main source of malignant growth-related morbidity and mortality throughout the world. It is apical of all new cancer incidences analyzed among females. However, Machine learning algorithms have given rise to progress across different domains. There are various diagnostic methods available for cancer detection. However, cancer detection through histopathological images is considered to be more accurate. In this research, we have proposed the Stacked Generalized Ensemble (SGE) approach for breast cancer classification into Invasive Ductal Carcinoma+ and Invasive Ductal Carcinoma-. SGE is inspired by the stacking model which utilizes output predictions. Here, SGE uses six deep learning models as level-0 learner models or sub-models and Logistic regression is used as Level – 1 learner or meta – learner model. Invasive Ductal Carcinoma dataset for histopathology images is used for experimentation. The results of the proposed methodology have been compared and analyzed with existing machine learning and deep learning methods. The results demonstrate that the proposed methodology performed exponentially good in image classification in terms of accuracy, precision, recall, and F1 measure.

StackBC: Deep learning and transfer learning techniques based stacking approach for accurate Invasive Ductal Carcinoma classification using histology images

2022 ◽  
pp. 1-12
Author(s):  
Amin Ul Haq ◽  
Jian Ping Li ◽  
Samad Wali ◽  
Sultan Ahmad ◽  
Zafar Ali ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Deep Learning ◽  
Transfer Learning ◽  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Early Recognition ◽  
Predictive Performance ◽  
Operating Characteristics ◽  
Data Set ◽  
Learning Techniques

Artificial intelligence (AI) based computer-aided diagnostic (CAD) systems can effectively diagnose critical disease. AI-based detection of breast cancer (BC) through images data is more efficient and accurate than professional radiologists. However, the existing AI-based BC diagnosis methods have complexity in low prediction accuracy and high computation time. Due to these reasons, medical professionals are not employing the current proposed techniques in E-Healthcare to effectively diagnose the BC. To diagnose the breast cancer effectively need to incorporate advanced AI techniques based methods in diagnosis process. In this work, we proposed a deep learning based diagnosis method (StackBC) to detect breast cancer in the early stage for effective treatment and recovery. In particular, we have incorporated deep learning models including Convolutional neural network (CNN), Long short term memory (LSTM), and Gated recurrent unit (GRU) for the classification of Invasive Ductal Carcinoma (IDC). Additionally, data augmentation and transfer learning techniques have been incorporated for data set balancing and for effective training the model. To further improve the predictive performance of model we used stacking technique. Among the three base classifiers (CNN, LSTM, GRU) the predictive performance of GRU are better as compared to individual model. The GRU is selected as a meta classifier to distinguish between Non-IDC and IDC breast images. The method Hold-Out has been incorporated and the data set is split into 90% and 10% for training and testing of the model, respectively. Model evaluation metrics have been computed for model performance evaluation. To analyze the efficacy of the model, we have used breast histology images data set. Our experimental results demonstrated that the proposed StackBC method achieved improved performance by gaining 99.02% accuracy and 100% area under the receiver operating characteristics curve (AUC-ROC) compared to state-of-the-art methods. Due to the high performance of the proposed method, we recommend it for early recognition of breast cancer in E-Healthcare.

scholarly journals Breast Cancer Detection using Residual Convolutional Neural Network and Weighted Loss

2019 ◽  
Vol 11 (2) ◽  
pp. 43
Author(s):  
Samuel Aji Sena ◽  
Panca Mudjirahardjo ◽  
Sholeh Hadi Pramono
Keyword(s):  
Breast Cancer ◽  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Cancer Detection ◽  
Ductal Carcinoma ◽  
Detection System ◽  
Breast Cancer Detection ◽  
University Of Pennsylvania ◽  
Training Approach

This research presents a breast cancer detection system using deep learning method. Breast cancer detection in a large slide of biopsy image is a hard task because it needs manual observation by a pathologist to find the malignant region. The deep learning model used in this research is made up of multiple layers of the residual convolutional neural network, and instead of using another type of classifier, a multilayer neural network was used as the classifier and stacked together and trained using end-to-end training approach. The system is trained using invasive ductal carcinoma dataset from the Hospital of the University of Pennsylvania and The Cancer Institute of New Jersey. From this dataset, 80% and 20% were randomly sampled and used as training and testing data respectively. Training a neural network on an imbalanced dataset is quite challenging. Weighted loss function was used as the objective function to tackle this problem. We achieve 78.26% and 78.03% for Recall and F1-Score metrics, respectively which are an improvement compared to the previous approach.

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