scholarly journals Retinal Dehydrogenase 1

2020 ◽  
Author(s):  
Keyword(s):  
Retinal Dehydrogenase

Cloning of a rat cDNA encoding retinal dehydrogenase isozyme type I and its expression in E. coli

Gene ◽  
1997 ◽  
Vol 191 (2) ◽  
pp. 167-172 ◽  
Author(s):  
Peter Penzes ◽  
Xianshu Wang ◽  
Zuzana Sperkova ◽  
Joseph L Napoli
Keyword(s):  
Type I ◽  
E Coli ◽  
Dehydrogenase Isozyme ◽  
Retinal Dehydrogenase

Localization of retinal dehydrogenase type 1 in the stomach and intestine

2000 ◽  
Vol 302 (3) ◽  
pp. 397-400 ◽  
Author(s):  
Andréa Frota-Ruchon ◽  
Mieczyslaw Marcinkiewicz ◽  
Pangala V. Bhat
Keyword(s):  
Retinal Dehydrogenase

scholarly journals Changing Patterns of Renal Retinal Dehydrogenase Expression Parallel Nephron Development in the Rat

1998 ◽  
Vol 46 (9) ◽  
pp. 1025-1032 ◽  
Author(s):  
Pangala V. Bhat ◽  
Mieczyslaw Marcinkiewicz ◽  
Yuan Li ◽  
Sylvie Mader
Keyword(s):  
Retinoic Acid ◽  
Kidney Development ◽  
Rat Kidney ◽  
Distribution Patterns ◽  
Cell Types ◽  
Adult Rat ◽  
Changing Patterns ◽  
Cell Growth And Differentiation ◽  
Retinal Dehydrogenase ◽  
Nephron Development

We have recently characterized a cytosolic aldehyde dehydrogenase from rat kidney that functions as a retinal dehydrogenase (RALDH) and have cloned the corresponding gene. RALDH catalyzes the oxidation of retinal to retinoic acid, which regulates cell growth and differentiation by activating retinoic acid receptors. In situ hybridization demonstrates that RALDH mRNA expression is prominent in kidney in 2-day-old rats, is detected in lung and in epithelia of several tissues, but is not found in liver tissue. Retinal dehydrogenase activity peaks in kidney at Day 2 after birth and decreases gradually until adulthood, correlating well with RALDH expression. Weaker activity is also detectable in lungs but not in liver. Notably, distribution patterns of RALDH in kidney tissues are dramatically altered during postnatal development (P). From P0 to P6, hybridization is essentially concentrated within the marginal nephrogenic zone of the cortex. Expression progresses to deeper cortical layers from P12 to P16 and is intense in the medulla at P42, and focal expression is still detectable in the cortex. Immunocytochemical localization of RALDH in neonatal kidney shows staining mostly in cortical zone convoluted tubules and in adult rat shows staining in segments of distal and proximal tubules. These data suggest an important role for RALDH in modulating retinoic acid levels in different cell types during rat kidney development. The changing patterns of RALDH expression mirror stages of nephron formation in the developing rat kidney, strongly suggesting a central role for RALDH and thus for retinoids in controlling kidney development.

scholarly journals Purification, crystallization and preliminary X-ray diffraction studies of retinal dehydrogenase type II

1998 ◽  
Vol 54 (4) ◽  
pp. 639-642 ◽  
Author(s):  
Audrey L. Lamb ◽  
Xianshu Wang ◽  
Joseph L. Napoli ◽  
Marcia E. Newcomer
Keyword(s):  
Type Ii ◽  
X Ray Diffraction ◽  
X Ray ◽  
Retinal Dehydrogenase

Enzymatic characteristics of retinal dehydrogenase type I expressed in Escherichia coli

1997 ◽  
Vol 1342 (2) ◽  
pp. 175-181 ◽  
Author(s):  
Peter Penzes ◽  
Xianshu Wang ◽  
Joseph L Napoli
Keyword(s):  
Escherichia Coli ◽  
Type I ◽  
Enzymatic Characteristics ◽  
Retinal Dehydrogenase

Postnatal changes in gene expression of retinal dehydrogenase and retinoid receptors in liver of rats

Life Sciences ◽  
2004 ◽  
Vol 74 (12) ◽  
pp. 1519-1528 ◽  
Author(s):  
Yuko Ogura ◽  
Kazuhito Suruga ◽  
Hiroko Mochizuki ◽  
Takeshi Yamamoto ◽  
Sachiko Takase ◽  
...  
Keyword(s):  
Gene Expression ◽  
Retinoid Receptors ◽  
Retinal Dehydrogenase

scholarly journals Cutting Edge: 4-1BB Controls Regulatory Activity in Dendritic Cells through Promoting Optimal Expression of Retinal Dehydrogenase

2012 ◽  
Vol 189 (6) ◽  
pp. 2697-2701 ◽  
Author(s):  
Seung-Woo Lee ◽  
Yunji Park ◽  
So-Young Eun ◽  
Shravan Madireddi ◽  
Hilde Cheroutre ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Cutting Edge ◽  
Regulatory Activity ◽  
Retinal Dehydrogenase

Kinetic characterization of recombinant mouse retinal dehydrogenase types 3 and 4 for retinal substrates

2009 ◽  
Vol 1790 (12) ◽  
pp. 1660-1664 ◽  
Author(s):  
Aurelia Sima ◽  
Maxime Parisotto ◽  
Sylvie Mader ◽  
Pangala V. Bhat
Keyword(s):  
Kinetic Characterization ◽  
Recombinant Mouse ◽  
Retinal Dehydrogenase

scholarly journals Low Retinal Dehydrogenase 1 (RALDH1) Level in Prepubertal Boys with Autism Spectrum Disorder: A Possible Link to Dopamine Dysfunction?

2017 ◽  
Vol 15 (3) ◽  
pp. 229-236 ◽  
Author(s):  
Denis Pavăl ◽  
Florina Rad ◽  
Răzvan Rusu ◽  
Alexandru-Ştefan Niculae ◽  
Horaţiu Alexandru Colosi ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Prepubertal Boys ◽  
Retinal Dehydrogenase

Increased hepatic retinal dehydrogenase activity after phenobarbital and ethanol administration

1989 ◽  
Vol 38 (1) ◽  
pp. 97-103 ◽  
Author(s):  
Maria Anna Leo ◽  
Cho-Il Kim ◽  
Nancy Lowe ◽  
Charles S. Lieber
Keyword(s):  
Dehydrogenase Activity ◽  
Ethanol Administration ◽  
Retinal Dehydrogenase
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