scholarly journals Rimantadine Hydrochloride

2020 ◽  
Author(s):  
Keyword(s):  
Rimantadine Hydrochloride

scholarly journals Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics.

1983 ◽  
Vol 23 (3) ◽  
pp. 458-464 ◽  
Author(s):  
F G Hayden ◽  
H E Hoffman ◽  
D A Spyker
Keyword(s):  
Side Effects ◽  
Rimantadine Hydrochloride

Suppression of Dengue Virus Replication in Vitro by Rimantadine Hydrochloride *

1981 ◽  
Vol 30 (1) ◽  
pp. 184-189 ◽  
Author(s):  
Wayne C. Koff ◽  
Joe L. Elm ◽  
Scott B. Halstead
Keyword(s):  
Dengue Virus ◽  
Virus Replication ◽  
Rimantadine Hydrochloride

Rimantadine Hydrochloride

1984 ◽  
Vol 9 (9) ◽  
pp. 660
Author(s):  
J. Castañer
Keyword(s):  
Rimantadine Hydrochloride

scholarly journals Comparative Single-Dose Pharmacokinetics of Amantadine Hydrochloride and Rimantadine Hydrochloride in Young and Elderly Adults

1986 ◽  
Vol 30 (3) ◽  
pp. 519-519
Author(s):  
F. G. Hayden ◽  
A. Minocha ◽  
D. A. Spyker ◽  
H. E. Hoffman
Keyword(s):  
Single Dose ◽  
Elderly Adults ◽  
Rimantadine Hydrochloride

scholarly journals Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults.

1986 ◽  
Vol 29 (2) ◽  
pp. 339-341 ◽  
Author(s):  
F G Hayden ◽  
A S Monto
Keyword(s):  
Influenza A Virus ◽  
Influenza A ◽  
H3n2 Subtype ◽  
Rimantadine Hydrochloride

Crystal Structure Explains Crystal Habit for the Antiviral Drug Rimantadine Hydrochloride

2014 ◽  
Vol 69 (7) ◽  
pp. 823-828 ◽  
Author(s):  
Anatoly Mishnev ◽  
Dmitrijs Stepanovs
Keyword(s):  
Crystal Structure ◽  
Symmetry Axis ◽  
Antiviral Drug ◽  
Structural Features ◽  
Unit Cell ◽  
Crystal Habit ◽  
Maximal Dimension ◽  
X Ray ◽  
Rimantadine Hydrochloride ◽  
Inner Channel

The crystal structure of the antiviral drug rimantadine hydrochloride, C12H22N+ Cl−, has been elucidated by a single-crystal X-ray structure analysis. The structure consists of 1-(1- adamantyl)ethanamine (rimantadinium) cations and chloride anions. The Cl− anions link the rimantadinium cations via N-H...Cl hydrogen bonds into infinite rectangular chord-like structural units with charged groups in the inner channel and aliphatic groups on the surface, and oriented along the unit cell c axis. In contrast to strong electrostatic and hydrogen bonding inner interactions the chords in the crystal are held together by weak van der Waals forces only. A two-fold symmetry axis passes through the center of the chord. By indexing of the crystal faces it has been shown that the maximal dimension of the needle-like crystals coincides with the direction of the unit cell c axis. These structural features explain the crystal habit and the anisotropy of the mechanical properties of rimantadine hydrochloride crystals observed upon slicing and cleavage.

Rimantadine hydrochloride blocks the second step of influenza virus uncoating

1980 ◽  
Vol 66 (3) ◽  
pp. 275-282 ◽  
Author(s):  
A. G. Bukrinskaya ◽  
N. K. Vorkunova ◽  
R. A. Narmanbetova
Keyword(s):  
Influenza Virus ◽  
Second Step ◽  
Rimantadine Hydrochloride ◽  
Virus Uncoating
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