scholarly journals Intratumoral Therapy

2020 ◽  
Author(s):  
Keyword(s):  
Intratumoral Therapy

Endoscopic transventricular positioning of intracystic catheter for treatment of craniopharyngioma

2009 ◽  
Vol 4 (3) ◽  
pp. 245-248 ◽  
Author(s):  
Benedetta L. Pettorini ◽  
Gianpiero Tamburrini ◽  
Luca Massimi ◽  
Massimo Caldarelli ◽  
Concezio Di Rocco
Keyword(s):  
Interferon Α ◽  
Ventricular Catheter ◽  
Endoscopic View ◽  
Frontal Horn ◽  
Control Tumor Growth ◽  
Intratumoral Therapy ◽  
Subcutaneous Space ◽  
Control Tumor ◽  
Harmful Effects ◽  
Intracystic Injection

The intracystic injection of chemo- and radiotherapeutic agents was introduced for the treatment of craniopharyngioma to control tumor growth and to delay the potentially harmful effects of surgery or radiation therapy. The positioning of cyst catheters has been performed by means of direct vision, stereotactically guided insertion, and ultrasonographic and ventriculoscopic guidance. The insertion of a catheter into the cyst is not devoid of complications, with an incidence ranging up to 16%, independent of the surgical technique used. Eight patients (mean age 25.8 years) with symptomatic cystic craniopharyngioma were treated by means of an endoscopic transventricular approach for the insertion of an intracystic catheter for intratumoral therapy with interferon-α. A single right precoronal bur hole is made, and the frontal horn of the lateral ventricle is accessed under neuronavigation guidance. A ventricular catheter with an inserted stylet was advanced anterior to the endoscope sheath through the same cortical access as the endoscope and was guided under endoscopic view down to the cyst dome wall. The coagulated surface of the craniopharyngioma cyst was punctured and the tip of the ventricular catheter was advanced; the depth was established preoperatively on MR scans and confirmed by neuronavigation guidance. The proximal end of the cystic catheter was connected to an access chamber to be left in the subcutaneous space, and the endoscope was slowly retracted. The authors' experience favors the use of neuroendoscopic positioning of intracystic catheters as safer than open and stereotactic approaches.

Intratumoral Therapy I: Association of Immunotherapy with Permanent Long Term Cure of Metastatic Cancer

2018 ◽  
Vol 07 (04) ◽  
Author(s):  
Max Cohen ◽  
Alfred Ketcham ◽  
Ronald Herberman
Keyword(s):  
Metastatic Cancer ◽  
Intratumoral Therapy

scholarly journals ATNT-03FIRST IN HUMAN STUDY OF RHENIUM NANOLIPOSOMES FOR INTRATUMORAL THERAPY OF GLIOMA

2015 ◽  
Vol 17 (suppl 5) ◽  
pp. v10.3-v10
Author(s):  
John Floyd ◽  
William Phillips ◽  
Beth Goins ◽  
Ande Bao ◽  
Andrew Brenner
Keyword(s):  
Human Study ◽  
Intratumoral Therapy

Intratumoral Therapy of Cisplatin/Epinephrine Injectable Gel for Palliation in Patients With Obstructive Esophageal Cancer

2000 ◽  
Vol 23 (4) ◽  
pp. 386-392 ◽  
Author(s):  
Satdarshan P. S. Monga ◽  
Robert Wadleigh ◽  
A. Sharma ◽  
Houtan Adib ◽  
Doris Strader ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Intratumoral Therapy

scholarly journals Endoscopic ultrasound.guided fine-needle tissue acquisition – A review and update of literature

2015 ◽  
Vol 06 (01) ◽  
pp. 001-010
Author(s):  
Benjamin Tharian ◽  
Nayana George ◽  
Ashley Canipe ◽  
Bronte Holt ◽  
Konrad Krall ◽  
...  
Keyword(s):  
Best Practices ◽  
Neoadjuvant Therapy ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Intratumoral Therapy ◽  
Tissue Acquisition ◽  
Indispensable Tool

AbstractEver since the first endoscopic ultrasound-guided fine needle aspiration (FNA) was done in 1992, the procedure has evolved to become an indispensable tool for tissue acquisition in patients with gastrointestinal tumors and periluminal lesions. With the growing evidence of neoadjuvant therapy and research into intratumoral therapy, the need to obtain tissue diagnosis for tumors is quite apparent. This review provides an overall perspective to the endosonographer on various issues that are a key for best practices in FNA, in addition to being an update for practicing experienced endosonographers.

Phase I trial of intratumoral therapy using HF10, an oncolytic HSV-1, demonstrates safety in HSV+/HSV- patients with refractory and superficial cancers.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 6082-6082 ◽  
Author(s):  
Robert L. Ferris ◽  
Neil D. Gross ◽  
John J. Nemunaitis ◽  
Robert Hans Ingemar Andtbacka ◽  
Athanassios Argiris ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Trial ◽  
Intratumoral Therapy ◽  
Hsv 1

Intratumoral Therapy II: In Vitro and In Vivo Immunologic Testing and Therapy Options

2018 ◽  
Vol 07 (04) ◽  
Author(s):  
Max Cohen ◽  
Alfred Ketcham ◽  
Ronald Herberman
Keyword(s):  
Therapy Options ◽  
Intratumoral Therapy

Intratumoral Therapy With Interferon-α in a Locoregional Advanced Malignant Blue Nevus

2010 ◽  
Vol 33 (1) ◽  
pp. 92-95 ◽  
Author(s):  
Roger von Moos ◽  
Reto Schaffner ◽  
Richard Cathomas ◽  
Birgit Grimm
Keyword(s):  
Interferon Α ◽  
Blue Nevus ◽  
Intratumoral Therapy
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