Class 1/4 Histone Deacetylase Inhibitor OKI-179

Mapping Intimacies ◽

10.32388/h3y959 ◽

2020 ◽

Author(s):

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Deacetylase Inhibitor ◽

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Randomized, double-blind, placebo-controlled phase II study of erlotinib with and without entinostat, a class 1 isoform selective histone deacetylase inhibitor (HDAC), in patients with advanced non-small cell lung cancer (NSCLC; ENCORE-401).

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.lba7532 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. LBA7532-LBA7532

Author(s):

R. Jotte ◽

S. E. Witta ◽

M. A. Neubauer ◽

A. I. Spira ◽

K. Konduri

Keyword(s):

Lung Cancer ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase Ii Study ◽

Small Cell Lung ◽

Double Blind ◽

Double Blind Placebo ◽

Deacetylase Inhibitor ◽

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A phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of CHR-3996, a class 1 selective histone deacetylase inhibitor (HDACi), in patients with advanced solid tumors.

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.2552 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. 2552-2552 ◽

Author(s):

U. Banerji ◽

L. van Doorn ◽

D. Papadatos-Pastos ◽

P. Debnam ◽

M. Tall ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Advanced Solid Tumors ◽

Deacetylase Inhibitor ◽

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Decision letter: MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice

10.7554/elife.52212.sa1 ◽

2020 ◽

Keyword(s):

Glycemic Control ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Deacetylase Inhibitor ◽

Class 1 ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1

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Author response: MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice

10.7554/elife.52212.sa2 ◽

2020 ◽

Author(s):

Shilpak Bele ◽

Shravan Babu Girada ◽

Aramita Ray ◽

Abhishek Gupta ◽

Srinivas Oruganti ◽

...

Keyword(s):

Glycemic Control ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Author Response ◽

Deacetylase Inhibitor ◽

Class 1 ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1

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Preliminary Phase II Data Suggest That Entinostat (SNDX275), a Class 1 Selective Histone Deacetylase Inhibitor (HDACi), May Resensitize Breast Cancer Patients Progressing on Aromataste Inhibitor (AI) Therapy to Their AI Therapy.

10.1158/0008-5472.sabcs-09-6111 ◽

2009 ◽

Author(s):

A. Wardley ◽

J. McCaffrey ◽

J. Crown ◽

R. Stein ◽

Z. Malik ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Histone Deacetylase ◽

Phase Ii ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Patients ◽

Deacetylase Inhibitor ◽

Class 1 ◽

Preliminary Phase

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Abstract 5439: Characterization of the class 1 histone deacetylase inhibitor entinostat in EGFRi acquired resistance models and in combination with cetuximab in NSCLC

10.1158/1538-7445.am10-5439 ◽

2010 ◽

Author(s):

Daniel C. Chan ◽

Samir E. Witta ◽

Di Zheng ◽

Veronika Franekova ◽

Xiaomei Sui ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Acquired Resistance ◽

Deacetylase Inhibitor ◽

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Phase II data for entinostat, a class 1 selective histone deacetylase inhibitor, in patients whose breast cancer is progressing on aromatase inhibitor therapy.

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.1052 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. 1052-1052 ◽

Author(s):

A. M. Wardley ◽

R. Stein ◽

J. McCaffrey ◽

J. Crown ◽

Z. Malik ◽

...

Keyword(s):

Breast Cancer ◽

Aromatase Inhibitor ◽

Histone Deacetylase ◽

Phase Ii ◽

Histone Deacetylase Inhibitor ◽

Inhibitor Therapy ◽

Aromatase Inhibitor Therapy ◽

Deacetylase Inhibitor ◽

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Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells

AIDS ◽

10.1097/qad.0000000000000067 ◽

2013 ◽

Vol 27 (18) ◽

pp. 2853-2862 ◽

Author(s):

Fiona Wightman ◽

Hao K. Lu ◽

Ajantha E. Solomon ◽

Suha Saleh ◽

Andrew N. Harman ◽

...

Keyword(s):

T Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Histone Deacetylases ◽

Deacetylase Inhibitor ◽

Class 1 ◽

Latently Infected

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Abstract B196: Entinostat: A novel class 1 isoform selective histone deacetylase inhibitor (HDACi) with unique pharmacological properties

10.1158/1535-7163.targ-09-b196 ◽

2009 ◽

Author(s):

Peter Ordentlich ◽

Gloria Lee ◽

Lori Kunkel ◽

Edward Sausville

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Pharmacological Properties ◽

Deacetylase Inhibitor ◽

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Electrocardiographic effects of class 1 selective histone deacetylase inhibitor romidepsin

Cancer Medicine ◽

10.1002/cam4.467 ◽

2015 ◽

Vol 4 (8) ◽

pp. 1178-1185 ◽

Author(s):

Philip T. Sager ◽

Barbara Balser ◽

Julie Wolfson ◽

Jean Nichols ◽

Richard Pilot ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Deacetylase Inhibitor ◽

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