Portuguese Water Dog | ScienceGate

Progressive rod-cone degeneration (PRCD) is a late onset autosomal photoreceptor degeneration found in canines. PRCD in canines is homologous to one form of retinitis pigmentosa (RP) found in humans and displays phenotypic similarity as well as having the identical causative mutation. The PRCD gene was mapped to the centromeric region of canine chromosome 9 (CFA9). We report here a population study of 699 dogs of the following breeds and the following frequencies of the disease-causing mutation: American Cocker Spaniel (0.09), English Cocker Spaniel (0.34), English Springer Spaniel (0.00), Welsh Springer Spaniel (0.00), Flat Coated Retriever (0.00), Golden Retriever (0.00), Chesapeake Bay Retriever (0.14), Nova Scotia Duck Tolling Retriever (0.44), Labrador Retriever (0.07), Poodle Toy (0.45), Poodle Miniature (0.20), Poodle Medium (0.05), Poodle Standard (0.00), Portuguese Water Dog (0.33), Chinese Crested Dog (0.02), Shipperke (0.06), and Australian Cattle Dog (0.00). The disease results in complete blindness in the affected individual in almost every case. The time of onset and disease progression varies between dog breeds as well as between individuals. A modifier gene is likely to segregate in genomic proximity to the PRCD gene and may influence phenotypic expression.

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Age relationships of postmortem observations in Portuguese Water Dogs

AGE ◽

10.1007/s11357-010-9181-5 ◽

2010 ◽

Vol 33 (3) ◽

pp. 461-473 ◽

Cited By ~ 10

Author(s):

Kevin Chase ◽

Dennis F. Lawler ◽

Lawrence D. McGill ◽

Shawn Miller ◽

Mark Nielsen ◽

...

Keyword(s):

Portuguese Water

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Metastatic thymoma in the liver of a dog

Journal of Veterinary Diagnostic Investigation ◽

10.1177/1040638718791222 ◽

2018 ◽

Vol 30 (5) ◽

pp. 774-778

Author(s):

Valerie Wiles ◽

Jamie Haddad ◽

Nicole Leibman ◽

Anne C. Avery ◽

Kelly L. Hughes

Keyword(s):

Flow Cytometry ◽

T Cell Receptor ◽

Mediastinal Mass ◽

Abdominal Ultrasound ◽

Cell Receptor ◽

Fine Needle ◽

Fine Needle Aspirates ◽

T Cell Receptor Genes ◽

History Of ◽

Portuguese Water

A 12-y-old neutered male Portuguese Water dog was presented because of a 1-y history of persistent hyporexia, diarrhea, and recurrent pyelonephritis. Abdominal ultrasound revealed hepatic nodules and diffuse splenomegaly, and radiographs revealed a mediastinal mass. Fine-needle aspirates of the liver, spleen, and mediastinal mass were suspicious for lymphoma. Flow cytometry identified small T cells that co-expressed CD4 and CD8 at all sites, most suspicious for thymoma, but lymphoma could not be ruled out. PCR for antigen receptor rearrangements analysis identified polyclonal amplification of the T-cell receptor genes, more consistent with thymoma than lymphoma. Histopathology of the liver and thymic mass confirmed thymoma with hepatic metastasis.

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Genetics Meets Proteomics: Correlating the Portuguese Water Dog Blood Serum Proteome with Genetic Markers

Proteomics Insights ◽

10.4137/pri.s6470 ◽

2011 ◽

Vol 4 ◽

pp. PRI.S6470

Author(s):

Sandra Sénéchal ◽

Martin Kussmann

Keyword(s):

Blood Serum ◽

Biomarker Discovery ◽

Protein Quantification ◽

Label Free ◽

Blood Profile ◽

Serum Proteome ◽

Genetic Level ◽

Portuguese Water ◽

Dog Blood ◽

Genetically Determined

Blood serum is a body fluid widely used for biomarker discovery and therefore numerous studies aim at defining its proteome. The serum proteome is subject to fluctuations resulting from biological variability (eg, diurnal variations) reflecting both healthy and/or disease-related conditions. Inter-individual differences originate partly at the genetic level and may influence clinical blood profile including the serum proteome. Therefore we investigated whether serum protein abundance is genetically determined: we report the study of a cohort of 146 Portuguese Water Dogs, a dog breed whose genetic background has been well characterized. We generated protein profiles of dog sera on 1D-gels and correlated them with microsatellite markers. We detected correlations between 7 gel bands and 11 genetic regions and developed a label-free protein quantification method to identify and quantify the proteins most accountable for serum proteome variation. An association between the abundance of RBP4 in dog serum and the adiponectin gene was detected.

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Data integration for infrastructure asset management in small to medium-sized water utilities

Water Science & Technology ◽

10.2166/wst.2020.377 ◽

2020 ◽

Vol 82 (12) ◽

pp. 2737-2744

Author(s):

N. Carriço ◽

B. Ferreira ◽

R. Barreira ◽

A. Antunes ◽

C. Grueau ◽

...

Keyword(s):

Information Management ◽

Asset Management ◽

Water Utilities ◽

Data Sets ◽

Sources Of Information ◽

Management Efficiency ◽

Portuguese Water ◽

And Performance ◽

Asset Managers ◽

Infrastructure Asset Management

Abstract Water utilities collect, store and manage vast data sets using many information systems (IS). For infrastructure asset management (IAM) planning those data need to be processed and transformed into information. However, information management efficiency often falls short of desired results. This happens particularly in municipalities where management is structured according to local government models. Along with the existing IS at the utilities' disposal, engineers and managers take their decisions based on information that is often incomplete, inaccurate or out-of-date. One of the main challenges faced by asset managers is integrating the several, often conflicting, sources of information available on the infrastructure, its condition and performance, and the various predictive analyses that can assist in prioritizing projects or interventions. This paper presents an overview of the IS used by Portuguese water utilities and discusses how data from different IS can be integrated in order to support IAM.

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Comparing private and public performance of Portuguese water services

Water Policy ◽

10.2166/wp.2007.033 ◽

2007 ◽

Vol 10 (1) ◽

pp. 25-42 ◽

Cited By ~ 45

Author(s):

Rui Cunha Marques

Keyword(s):

Empirical Studies ◽

Data Envelopment ◽

Water Services ◽

Public Performance ◽

Private Companies ◽

The Public ◽

Private And Public ◽

Portuguese Water ◽

Private Management

This article compares the performance of the Portuguese water services (WS) according to their ownership. Several techniques, such as performance indicators, total factor productivity and data envelopment analysis were used. First, the paper describes the water sector institutional framework in Portugal. Then, it reviews the major theories that relate performance to WS ownership and the main empirical studies developed in this area. Finally, it presents the case study. The conclusions drawn from the study seem to prove the outperformance of the WS under private management in Portugal when compared with the public ones. The quality of service provided by the former is better than that of the latter, which is particularly evident with regard to water quality. Productivity is also superior in private companies. However, the results suggest an opposite trend as far as efficiency is concerned.

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