scholarly journals Herpes Zoster: Clinical Manifestation, Treatment, and Prevention

2020 ◽  
Vol 4 (3) ◽  
pp. 34-44
Author(s):  
Muhammad Izazi Hari Purwoko ◽  
Hari Darmawan
Keyword(s):  
Herpes Zoster ◽  
High Risk ◽  
Varicella Zoster Virus ◽  
The Elderly ◽  
Prevention Strategies ◽  
Zoster Vaccine ◽  
Varicella Zoster ◽  
Treatment And Prevention ◽  
Varicella Zoster Virus Vaccine ◽  
Recombinant Zoster Vaccine

Herpes zoster (HZ, shingles, zoster) is a disease due to reactivation and multiplication of persistent varicella zoster virus (VVZ) after suffering from previous varicella with characteristics of dermatomal rashes, pain, and unilateral. Dermatoms most often involved in HZ lesions are thoracal, trigeminal, lumbal, and cervical. The first lesion is usually erythematous macule or papule, which then turns into vesicle, then to pustule and to become crust, and persists for 2-3 weeks. The main goal of antiviral therapy in HZ patients is to reduce the expansion, duration, and severity of rashes and pain in primary dermatomes; prevent the spread of HZ to other places; and prevent post-herpes neuralgia. One of the prevention strategies for HZ in the elderly and high-risk individuals is vaccination using the varicella zoster virus vaccine that is live zoster vaccine or recombinant zoster vaccine.

scholarly journals Human Vaccines and Herpes Zoster Ophthalmicus: Clinical Manifestation, Treatment, and Prevention

2020 ◽  
Vol 8 (F) ◽  
pp. 203-207
Author(s):  
Vina Yuwanda
Keyword(s):  
Herpes Zoster ◽  
Immunosuppressive Agents ◽  
Antibody Detection ◽  
Zoster Vaccine ◽  
Herpes Zoster Ophthalmicus ◽  
Varicella Zoster ◽  
Ocular Manifestations ◽  
Treatment And Prevention ◽  
Control And Prevention ◽  
Recombinant Zoster Vaccine

Herpes zoster ophthalmicus (HZO) is a reactivation of HZ virus that is latent in ophthalmic division of trigeminal ganglion. Patients over 50 years old, premature infant, pregnancy woman, receiving immunosuppressive agents, and malignancies are at risk of having HZO. Ocular manifestations of HZ are ectropion, entropion, ectopic eyelash, keratitis, conjunctivitis, symblepharon, hypoesthesia, episcleritis, scleritis, scleral atrophy and thinning, uveitis, iris atrophy, posterior synechiae, acute retinal necrosis, progressive outer retinal necrosis, retinal detachment, retina atrophy, optic neuritis, optic atrophy, and strabismus. Polymerase chain reaction, antigen detection, and antibody detection can help to confirm diagnosis. Pharmacology treatments for HZ ophthalmicus are antiviral drugs, corticosteroids, analgesics, tricyclic antidepressants, and antiepileptic drug. Non-pharmacology therapies are scleral contact lens, phototherapeutic keratectomy, photorefractive keratectomy, and penetrating keratoplasty. There are two kinds of vaccination which can be given to patients: Live-attenuated varicella zoster vaccine and recombinant zoster vaccine. It is recommended by Centers for Disease Control and Prevention and Food and Drugs Administration to use recombinant zoster vaccine by 50 years old.

scholarly journals Varicella‐Zoster Virus–Specific Immune Responses to Herpes Zoster in Elderly Participants in a Trial of a Clinically Effective Zoster Vaccine

2009 ◽  
Vol 200 (7) ◽  
pp. 1068-1077 ◽  
Author(s):  
Adriana Weinberg ◽  
Jane H. Zhang ◽  
Michael N. Oxman ◽  
Gary R. Johnson ◽  
Anthony R. Hayward ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Immune Responses ◽  
Varicella Zoster Virus ◽  
Zoster Vaccine ◽  
Varicella Zoster

scholarly journals Varicella-Zoster Virus DNA in Blood After Administration of Herpes Zoster Vaccine

2018 ◽  
Vol 217 (7) ◽  
pp. 1055-1059 ◽  
Author(s):  
Myron J Levin ◽  
Guang-Yun Cai ◽  
Katherine S Lee ◽  
Nadine G Rouphael ◽  
Aneesh K Mehta ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Zoster Vaccine ◽  
Varicella Zoster

scholarly journals Herpes Zoster Caused by Vaccine-Strain Varicella Zoster Virus in an Immunocompetent Recipient of Zoster Vaccine

2014 ◽  
Vol 58 (8) ◽  
pp. 1125-1128 ◽  
Author(s):  
H. F. Tseng ◽  
D. S. Schmid ◽  
R. Harpaz ◽  
P. LaRussa ◽  
N. J. Jensen ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Vaccine Strain ◽  
Zoster Vaccine ◽  
Varicella Zoster
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