Urological Causes of Male Infertility and Erectile Dysfunction

Author(s):  
Abimbola Abolarinwa
2004 ◽  
Vol 171 (4S) ◽  
pp. 369-369
Author(s):  
Jeanne H. O'Brien ◽  
Ben Bowles ◽  
Stephen Lazarou ◽  
Keith A. Jarvi ◽  
Armand Zini

2019 ◽  
Vol 14 (5) ◽  
pp. 321-334 ◽  
Author(s):  
Giulia Rastrelli ◽  
Francesco Lotti ◽  
Yacov Reisman ◽  
Alessandra Sforza ◽  
Mario Maggi ◽  
...  

1999 ◽  
Vol 80 (10) ◽  
pp. 1331-1339 ◽  
Author(s):  
Manoj Monga ◽  
Jonathan Bernie ◽  
Mahadevan Rajasekaran

2018 ◽  
Vol 5 (8) ◽  
pp. 2862
Author(s):  
Junaid Alam ◽  
Pawan Choudhary ◽  
Mohammad Aslam

Background: Infertility is a condition with psychological, economic, medical implications resulting in mental trauma, stress particularly in social set up like ours, with strong emphasis on child bearing. According to the International Committee for Monitoring Assisted Reproductive Technology, World Health Organization (WHO), Infertility is disease of reproductive system defined by failure to achieve the clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.Methods: This study was conducted in Department of Surgery in Jawaharlal Nehru Medical College, Aligarh from January 2017 to December 2017 on 120 patients to study the clinical profile, causes of male infertility and to evaluate the risk factors associated with it.Results: There were 54 (45%) patients with azoospermia and 66 (55%) had oligospermia. Out of them 52 (43.3%) had sperm counts of 1-8 millions/ml and 14 (11.6%) had sperm count between >9-15 millions/ml. 46 (38.3%) patients had low testosterone level. 86 of cases had motility <50% after one hour, remaining 34 had motility >50%. Out of 120 cases of male infertility, 12 (10%) had Obesity and rest 108 (90%) had normal BMI. Out of 120 cases of male infertility, 8 (6.6%) were known Diabetics rest 112 (93.3%) had normal blood sugar levels. Out of 120 cases of male infertility, 36 (30%) had Erectile dysfunction and rest 84 (70%) were normal.Conclusions: The study concluded that Erectile dysfunction was the most common cause of male infertility. Varicoceles and small sized testes were the most common clinical abnormalities seen in infertile males. Smoking, Alcohol and Tobacco use were frequently associated with most infertile males.


2022 ◽  
Vol 12 ◽  
Author(s):  
Yi Lu ◽  
Hao Su ◽  
Jianzhong Zhang ◽  
Yutao Wang ◽  
Hongjun Li

Background: Pentoxifylline (PTX) is a member of methylxanthine chemicals and a type of non-selective phosphodiesterase-5 inhibitors, which has been used in male infertility treatment to improve sperm quality and erectile dysfunction (ED) treatment. Mutually tight associations existed between ED and male infertility. Using PTX might kill two birds with one stone by improving sperm quality and erectile function in infertile men with ED.Methods: PubMed, Cochrane Library, EMBASE, and Web of Science were searched by October 2021. Based on available evidence from observational studies and randomized-controlled trials (RCTs), we conducted a systematic review to summarize the efficacy and safety of PTX in treating ED and male infertility. The protocol of the article was registered and updated in PROSPERO (CRD42021291396).Results: From 202 records, eight studies (7 RCTs) evaluating the role of PTX in ED and three studies (2 RCTs) assessing the efficacy of PTX in male infertility were included in the systematic review. Three studies (100.00%) and two studies (100.00%) reported the beneficial role of PTX in improving sperm progressive motility and normal sperm morphology rate, respectively. In contrast, only one study (33.33%) indicated the favorable role of PTX in enhancing sperm concentration. As for ED, three (60.00%) studies supported the treatment role of PTX alone in ED, and two studies (66.67%) favored the combination use of PTX and selective PDE5Is compared with selective PDE5Is alone. Safety analysis showed that PTX was a well-tolerated drug in ED and male infertility treatment.Conclusion: Given the association between ED and male infertility and satisfying findings from available evidence, PTX administration for the simultaneous treatment of poor sperm quality and mild ED in infertile men will highly enhance the treatment compliance. However, the finding should be treated carefully until validated by further studies.


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