scholarly journals Microbial Transformations of 3-methoxyflavone by the Strains of Aspergillus niger

2014 ◽  
Vol 63 (1) ◽  
pp. 111-114 ◽  
Author(s):  
EDYTA KOSTRZEWA-SUSŁOW ◽  
MONIKA DYMARSKA ◽  
TOMASZ JANECZKO

Microbial transformation of 3-methoxyflavone into 3'-hydroxyflavon-3-yloxymethyl myristate was presented. Six filamentous fungi were used as biocatalysts: a wild strain of Aspergillus niger KB, its four UV mutants (A. niger MB, SBP, SBJ, 13/5) and the strain of Penicillium chermesinum 113. The highest yields were observed for the strains of A. niger KB and A. niger SBP (69.8% and 63.1%, respectively).

2014 ◽  
Vol 106 (2) ◽  
pp. 197-209 ◽  
Author(s):  
Yesupatham Sathishkumar ◽  
Natarajan Velmurugan ◽  
Hyun Mi Lee ◽  
Kalyanaraman Rajagopal ◽  
Chan Ki Im ◽  
...  

2008 ◽  
Vol 63 (7-8) ◽  
pp. 561-564 ◽  
Author(s):  
Abou-El-Hamd H Mohamed ◽  
Ali K. Khalafallah ◽  
Afifi H. Yousof

Microbial transformation of glabratephrin, the major isolated compound from Tephrosia purpurea, afforded pseudosemiglabrin. The formation of the transformed compound seems to be performed via ring opening-closure of a five-membered ring causing transformation from a spiro into a fused system. The structure of the transformed compound was determined by comprehensive NMR studies, including DEPT, COSY, HMQC, NOE and MS.


2010 ◽  
Vol 5 (9) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Yoshiaki Noma ◽  
Yoshinori Asakawa

The biotransformation of (-)-nopol benzyl ether (5) by Aspergillus Niger TBUYN-2 and A. niger Tiegh CBSYN was investigated. A. niger biotransformed 5 to afford (-)-4-oxonopol-2’,4’-dihydroxybenzyl ether (6), and (-)-4-oxonopol (7) as main products. Compound 6 showed strong antioxidant activity (IC50 30.2 μM), which was very similar to that of butyl hydroxyl anisol (BHA).


2015 ◽  
Vol 14 (6) ◽  
pp. 602-615 ◽  
Author(s):  
Bert-Ewald Priegnitz ◽  
Ulrike Brandt ◽  
Khomaizon A. K. Pahirulzaman ◽  
Jeroen S. Dickschat ◽  
André Fleißner

ABSTRACTAdaptation to a changing environment is essential for the survival and propagation of sessile organisms, such as plants or fungi. Filamentous fungi commonly respond to a worsening of their growth conditions by differentiation of asexually or sexually produced spores. The formation of these specialized cell types is, however, also triggered as part of the general life cycle by hyphal age or density. Spores typically serve for dispersal and, therefore, translocation but can also act as resting states to endure times of scarcity. Eukaryotic differentiation in response to environmental and self-derived signals is commonly mediated by three-tiered mitogen-activated protein (MAP) kinase signaling cascades. Here, we report that the MAP kinase Fus3 of the black moldAspergillus niger(AngFus3) and its upstream kinase AngSte7 control vegetative spore formation and secondary metabolism. Mutants lacking these kinases are defective in conidium induction in response to hyphal density but are fully competent in starvation-induced sporulation, indicating that conidiation inA. nigeris triggered by various independent signals. In addition, the mutants exhibit an altered profile of volatile metabolites and secrete dark pigments into the growth medium, suggesting a dysregulation of the secondary metabolism. By assigning the AngFus3 MAP kinase pathway to the transduction of a potentially self-derived trigger, this work contributes to the unraveling of the intricate signaling networks controlling fungal differentiation. Moreover, our data further support earlier observations that differentiation and secondary metabolism are tightly linked in filamentous fungi.


2011 ◽  
Vol 79 (5) ◽  
pp. 1151-1167 ◽  
Author(s):  
Min Jin Kwon ◽  
Mark Arentshorst ◽  
Eelke D. Roos ◽  
Cees A. M. J. J. van den Hondel ◽  
Vera Meyer ◽  
...  

1986 ◽  
Vol 49 (1) ◽  
pp. 126-132 ◽  
Author(s):  
Andrés García-Granados ◽  
Antonio Martínez ◽  
M. Esther Onorato ◽  
Jose M. Arias

1990 ◽  
Vol 36 (9) ◽  
pp. 625-630 ◽  
Author(s):  
P. Vanacker ◽  
B. Bacle ◽  
G. Vidal ◽  
L. Lacoste

We have searched for producers of a saccharifying activity with improved thermostability compared with industrial amyloglucosidases. These producers were chosen among thermophilic, thermotolerant, or even mesophilic fungi. Among the 846 isolated strains, five species (two Thermoascus spp., a member of the Aspergillus fumigatus group, and two members of the Aspergillus niger group) showed an amyloglucosidasic complex with the required property. Whereas the first three of these were thermophilic or thermotolerant strains, the latter two strengthen the idea that mesophilic strains can produce thermostable enzymes. The thermostability of the saccharifying complex of the Thermoascus spp., established with a half-life measure, was found to be far better than the other ones. The industrial use of these strains was discussed, and Thermoascus crustaceus seems to be the most advantageous one. Key words: filamentous fungi, amyloglucosidases, thermostability, Thermoascus.


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