Open-label, randomised, parallel-group, multicentre study to evaluate the safety, tolerability and immunogenicity of an AS03B/oil-in-water emulsion-adjuvanted (AS03B) split-virion versus non-adjuvanted whole-virion H1N1 influenza vaccine in UK children 6 months to 12 years of age

CS Waddington; N Andrews; K Hoschler; WT Walker; C Oeser; A Reiner; T John; S Wilkins; M Casey; PE Eccleston; RJ Allen; I Okike; S Ladhani,; E Sheasby; P Waight; AC Collinson; PT Heath; A Finn; SN Faust; MD Snape; E Miller; AJ Pollard

doi:10.3310/hta14460-01

Open-label, randomised, parallel-group, multicentre study to evaluate the safety, tolerability and immunogenicity of an AS03B/oil-in-water emulsion-adjuvanted (AS03B) split-virion versus non-adjuvanted whole-virion H1N1 influenza vaccine in UK children 6 months to 12 years of age

Health Technology Assessment ◽

10.3310/hta14460-01 ◽

2010 ◽

Vol 14 (46) ◽

Cited By ~ 11

Author(s):

CS Waddington ◽

N Andrews ◽

K Hoschler ◽

WT Walker ◽

C Oeser ◽

...

Keyword(s):

Influenza Vaccine ◽

Multicentre Study ◽

H1n1 Influenza ◽

Open Label ◽

Water Emulsion ◽

Parallel Group ◽

Oil In Water ◽

Oil In Water Emulsion

Download Full-text

Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study

BMJ ◽

10.1136/bmj.c2649 ◽

2010 ◽

Vol 340 (may27 1) ◽

pp. c2649-c2649 ◽

Cited By ~ 130

Author(s):

C. S. Waddington ◽

W. T. Walker ◽

C. Oeser ◽

A. Reiner ◽

T. John ◽

...

Keyword(s):

Influenza Vaccine ◽

Multicentre Study ◽

H1n1 Influenza ◽

Open Label ◽

Parallel Group

Download Full-text

A novel oil-in-water emulsion as a potential adjuvant for influenza vaccine: Development, characterization, stability and in vivo evaluation

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2014.04.003 ◽

2014 ◽

Vol 468 (1-2) ◽

pp. 187-195 ◽

Cited By ~ 12

Author(s):

JiaHua Deng ◽

WeiHui Cai ◽

Fang Jin

Keyword(s):

Influenza Vaccine ◽

Vaccine Development ◽

In Vivo Evaluation ◽

Water Emulsion ◽

Oil In Water ◽

Oil In Water Emulsion

Download Full-text

Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania

Vaccine ◽

10.1016/j.vaccine.2012.10.048 ◽

2013 ◽

Vol 31 (12) ◽

pp. 1633-1640 ◽

Cited By ~ 10

Author(s):

Christopher B. Fox ◽

Chuong Huynh ◽

Michael K. O’Hara ◽

Adrian Onu

Keyword(s):

Technology Transfer ◽

Influenza Vaccine ◽

Pandemic Influenza ◽

Vaccine Production ◽

Water Emulsion ◽

Oil In Water ◽

Influenza Vaccine Production ◽

Oil In Water Emulsion

Download Full-text

Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania: Preclinical evaluation of split virion inactivated H5N1 vaccine with adjuvant

Human Vaccines & Immunotherapeutics ◽

10.1080/21645515.2015.1111495 ◽

2015 ◽

Vol 12 (4) ◽

pp. 1009-1026 ◽

Cited By ~ 6

Author(s):

Crina Stavaru ◽

Adrian Onu ◽

Emilia Lupulescu ◽

Catalin Tucureanu ◽

Orhan Rasid ◽

...

Keyword(s):

Technology Transfer ◽

Influenza Vaccine ◽

Pandemic Influenza ◽

Vaccine Production ◽

Water Emulsion ◽

Preclinical Evaluation ◽

Oil In Water ◽

Influenza Vaccine Production ◽

Oil In Water Emulsion ◽

H5n1 Vaccine

Download Full-text

Development of a novel oil-in-water emulsion and evaluation of its potential adjuvant function in a swine influenza vaccine in mice

BMC Veterinary Research ◽

10.1186/s12917-018-1719-2 ◽

2018 ◽

Vol 14 (1) ◽

Cited By ~ 4

Author(s):

Jinqiu Zhang ◽

Jinfeng Miao ◽

Xiangan Han ◽

Yu Lu ◽

Bihua Deng ◽

...

Keyword(s):

Influenza Vaccine ◽

Swine Influenza ◽

Water Emulsion ◽

Oil In Water ◽

Oil In Water Emulsion

Download Full-text

Oil-in-Water Emulsion Adjuvant with Influenza Vaccine in Young Children

New England Journal of Medicine ◽

10.1056/nejmoa1010331 ◽

2011 ◽

Vol 365 (15) ◽

pp. 1406-1416 ◽

Cited By ~ 215

Author(s):

Timo Vesikari ◽

Markus Knuf ◽

Peter Wutzler ◽

Aino Karvonen ◽

Dorothee Kieninger-Baum ◽

...

Keyword(s):

Young Children ◽

Influenza Vaccine ◽

Water Emulsion ◽

Oil In Water ◽

Oil In Water Emulsion

Download Full-text

Faculty Opinions recommendation of Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12236959.13406059 ◽

2011 ◽

Author(s):

Luigi Buonaguro ◽

Maria Tagliamonte

Keyword(s):

Nlrp3 Inflammasome ◽

Adaptor Protein ◽

Water Emulsion ◽

Oil In Water ◽

Oil In Water Emulsion

Download Full-text

Pharmacokinetics of an Oil-in-Water Emulsion Containing Isocarbacyclin Methyl Ester, TTC-909. (3). Tissue Distribution in Rats after Single Intravenous Administration.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.10.332 ◽

1995 ◽

Vol 10 (3) ◽

pp. 332-343

Author(s):

Yoshiro KOHNO ◽

Toshiya MINAGAWA ◽

Toshio SUWA ◽

Shiro KONDO ◽

Yoshio ESUMI ◽

...

Keyword(s):

Methyl Ester ◽

Tissue Distribution ◽

Intravenous Administration ◽

Water Emulsion ◽

Oil In Water ◽

Oil In Water Emulsion ◽

Single Intravenous Administration

Download Full-text

Natural killer cells contribute to enhanced respiratory disease after oil-in-water emulsion adjuvanted vaccination against respiratory syncytial virus and infection

Human Vaccines & Immunotherapeutics ◽

10.1080/21645515.2021.1915039 ◽

2021 ◽

pp. 1-12

Author(s):

Yoonsuh Park ◽

Ki-Hye Kim ◽

Youri Lee ◽

Young-Tae Lee ◽

Sang-Moo Kang ◽

...

Keyword(s):

Respiratory Syncytial Virus ◽

Natural Killer Cells ◽

Natural Killer ◽

Respiratory Disease ◽

Killer Cells ◽

Water Emulsion ◽

Oil In Water ◽

Syncytial Virus ◽

Oil In Water Emulsion

Download Full-text

Enhancing oil-in-water emulsion separation performance of polyvinyl alcohol hydrogel nanofibrous membrane by squeezing coalescence demulsification

Journal of Membrane Science ◽

10.1016/j.memsci.2021.119324 ◽

2021 ◽

pp. 119324

Author(s):

Xu Zhu ◽

Lei Zhu ◽

Hui Li ◽

Chunyu Zhang ◽

Jinwei Xue ◽

...

Keyword(s):

Polyvinyl Alcohol ◽

Nanofibrous Membrane ◽

Separation Performance ◽

Water Emulsion ◽

Oil In Water ◽

Emulsion Separation ◽

Oil In Water Emulsion

Download Full-text