scholarly journals Enhancements to angioplasty for peripheral arterial occlusive disease: systematic review, cost-effectiveness assessment and expected value of information analysis

2014 ◽  
Vol 18 (10) ◽  
Author(s):  
Emma L Simpson ◽  
Benjamin Kearns ◽  
Matthew D Stevenson ◽  
Anna J Cantrell ◽  
Chris Littlewood ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cost Effectiveness ◽  
Peripheral Arterial Occlusive Disease ◽  
Value Of Information ◽  
Arterial Occlusive Disease ◽  
Information Analysis ◽  
Expected Value Of Information ◽  
Peripheral Arterial ◽  
Effectiveness Assessment ◽  
Cost Effectiveness Assessment

scholarly journals Subintimal Angioplasty for Peripheral Arterial Occlusive Disease: A Systematic Review

2008 ◽  
Vol 31 (4) ◽  
pp. 687-697 ◽  
Author(s):  
Rosemarie Met ◽  
Krijn P. Van Lienden ◽  
Mark J. W. Koelemay ◽  
Shandra Bipat ◽  
Dink A. Legemate ◽  
...  
Keyword(s):  
Systematic Review ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Subintimal Angioplasty ◽  
Peripheral Arterial

scholarly journals Systematic review and meta-analysis of additional technologies to enhance angioplasty for infrainguinal peripheral arterial occlusive disease

2013 ◽  
Vol 100 (9) ◽  
pp. 1128-1137 ◽  
Author(s):  
E. L. Simpson ◽  
J. A. Michaels ◽  
S. M. Thomas ◽  
A. J. Cantrell
Keyword(s):  
Systematic Review ◽  
Peripheral Arterial Occlusive Disease ◽  
Meta Analysis ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Peripheral Arterial

scholarly journals Factors influencing quality of life following lower limb amputation for peripheral arterial occlusive disease: A systematic review of the literature

2017 ◽  
Vol 41 (6) ◽  
pp. 537-547 ◽  
Author(s):  
Fiona Davie-Smith ◽  
Elaine Coulter ◽  
Brian Kennon ◽  
Sally Wyke ◽  
Lorna Paul
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Lower Limb ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Lower Limb Amputation ◽  
Limb Amputation ◽  
Peripheral Arterial

Background: The majority of lower limb amputations are undertaken in people with peripheral arterial occlusive disease, and approximately 50% have diabetes. Quality of life is an important outcome in lower limb amputations; little is known about what influences it, and therefore how to improve it. Objectives: The aim of this systematic review was to identify the factors that influence quality of life after lower limb amputation for peripheral arterial occlusive disease. Methods: MEDLINE, EMBASE, CINAHL, PsycINFO, Web of Science and Cochrane databases were searched to identify articles that quantitatively measured quality of life in those with a lower limb amputation for peripheral arterial occlusive disease. Articles were quality assessed by two assessors, evidence tables summarised each article and a narrative synthesis was performed. Study design: Systematic review. Results: Twelve articles were included. Study designs and outcome measures used varied. Quality assessment scores ranged from 36% to 92%. The ability to walk successfully with a prosthesis had the greatest positive impact on quality of life. A trans-femoral amputation was negatively associated with quality of life due to increased difficulty in walking with a prosthesis. Other factors such as older age, being male, longer time since amputation, level of social support and presence of diabetes also negatively affected quality of life. Conclusion: Being able to walk with a prosthesis is of primary importance to improve quality of life for people with lower limb amputation due to peripheral arterial occlusive disease. To further understand and improve the quality of life of this population, there is a need for more prospective longitudinal studies, with a standardised outcome measure. Clinical relevance This is of clinical relevance to those who are involved in the rehabilitation of persons with lower limb amputations. Improved quality of life is associated with successful prosthetic use and focus should be directed toward achieving this.

Cost-Effective Strategies for the Management of Vascular Disease

1997 ◽  
Vol 2 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Jeffrey A West
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cost Effectiveness ◽  
Coronary Artery ◽  
Peripheral Arterial Occlusive Disease ◽  
Cost Effectiveness Analysis ◽  
Arterial Occlusive Disease ◽  
Effectiveness Analysis ◽  
Artery Disease ◽  
Peripheral Arterial

Cardiovascular disease accounts for over 950 000 deaths and an estimated $151 billion in direct and indirect costs. Because of this escalating clinical and financial burden, economic analysis has become essential for the evaluation of preventative therapies for vascular disease. Economic analysis compares competing interventions or management strategies for costs and benefits; more specifically, cost-effectiveness analysis compares cost in financial terms like dollars to measures of effectiveness like years of life saved. Important concepts in the creation of a valid cost-effectiveness analysis include perspective, time horizon, measurement of costs and effectiveness and sensitivity analysis. In patients with peripheral arterial occlusive disease, most morbidity and mortality arises from complications of coronary artery disease. Because coronary artery disease and peripheral arterial occlusive disease commonly occur together and share risk factors, pathophysiology and response to preventative therapy, economic evaluations of preventative therapies for coronary artery disease have relevance for patients with vascular disease. Cost-effectiveness analysis reveals that modification of vascular risk factors like tobacco use, hypertension and hypercholesterolemia improve clinical outcomes at acceptable cost-effectiveness ratios, usually less than $20 000 per year of life saved. More importantly, interventions like smoking cessation or lipid modification in high-risk groups may be cost saving, with treatment costs outweighed by financial benefits. From the patient, clinician and societal perspective, cost-effectiveness analysis supports the aggressive modification of cardiovascular risk factors in patients with peripheral arterial occlusive disease.

scholarly journals Quality Indicators in Peripheral Arterial Occlusive Disease Treatment: A Systematic Review

2019 ◽  
Vol 58 (5) ◽  
pp. 738-745 ◽  
Author(s):  
Sandra Hischke ◽  
Henrik C. Rieß ◽  
Maria K. Bublitz ◽  
Levente Kriston ◽  
Thea Schwaneberg ◽  
...  
Keyword(s):  
Systematic Review ◽  
Quality Indicators ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Disease Treatment ◽  
Peripheral Arterial

scholarly journals The Association of Periodontitis and Peripheral Arterial Occlusive Disease—A Systematic Review

2019 ◽  
Vol 20 (12) ◽  
pp. 2936 ◽  
Author(s):  
Mark Kaschwich ◽  
Christian-Alexander Behrendt ◽  
Guido Heydecke ◽  
Andreas Bayer ◽  
Eike Sebastian Debus ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Peripheral Arterial Occlusive Disease ◽  
Case Series ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Pubmed Database ◽  
Peripheral Arterial ◽  
Meta Analyses ◽  
Degrees Of Severity

Background: Observational studies support an association between periodontitis (PD) and atherosclerotic vascular disease, but little is known specifically about peripheral arterial occlusive disease (PAOD). Objectives: To systematically review the evidence for an association between PD and PAOD. Data Sources: Medline via PubMed. Review Methods: We searched the Pubmed database for original studies, case reports, case series, meta-analyses and systematic reviews that assessed whether there is an association between PD (all degrees of severity) and PAOD (all degrees of severity). The reporting of this systematic review was in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement following the Population, Intervention, Control, and Outcome (PICO) format. Results: 17 out of 755 detected studies were included in the qualitative synthesis. Nine studies demonstrated associations between PD and PAOD, and two studies reported associations between tooth loss and PAOD. Six studies addressed the pathomechanism regarding PD as a possible trigger for PAOD. No study that dismissed an association could be detected. Odds ratios or hazard ratios ranged from 1.3 to 3.9 in four large cohort studies after adjusting for established cardiovascular risk factors. Conclusions: The presented evidence supports a link between PD and PAOD. Further studies which address the temporality of PD and PAOD and randomized controlled intervention trials examining the causal impact of PD on PAOD are needed. Although our results cannot confirm a causal role of PD in the development of PAOD, it is likely that PD is associated with PAOD and plays a contributing role.

High prevalence of peripheral arterial occlusive disease (PAOD) in patients with obstructive sleep apnea

Pneumologie ◽  
2012 ◽  
Vol 66 (S 01) ◽  
Author(s):  
G Vogel ◽  
C Schäfer ◽  
L Adam ◽  
J Weisser-Thomas ◽  
C Hammerstingl ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Obstructive Sleep ◽  
High Prevalence ◽  
Peripheral Arterial

Causes and the way of treatment of patients with chronic leg ulcers

Phlebologie ◽  
2009 ◽  
Vol 38 (05) ◽  
pp. 211-218 ◽  
Author(s):  
C. Wax ◽  
A. Körber ◽  
J. Dissemond ◽  
J. Klode
Keyword(s):  
Treatment Period ◽  
General Practitioners ◽  
Peripheral Arterial Occlusive Disease ◽  
Mean Value ◽  
Arterial Occlusive Disease ◽  
Leg Ulcer ◽  
Leg Ulcers ◽  
Patient Will ◽  
Peripheral Arterial ◽  
Chronic Leg Ulcers

SummaryChronic leg ulcer may have various causes, which are currently not centrally recorded in Germany. It is also unclear who treats patients with chronic leg ulcers in Germany and how the basic implementation of diagnosis and treatment of these patients looks like. Patients, methods: Therefore, we started a survey of 1000 general practitioners and practising specialists in dermatology, surgery and phlebology in five different regions of Germany. We carried out the genesis of a total of 6275 patients from 62 different practising therapists, 33 specialists in dermatology, surgery or phlebology and 29 general practitioners. Results: In 66.1% of all patients we found a venous leg ulcer, in 9.1% a leg ulcer from peripheral arterial occlusive disease, and in 8.5% a mixture of both. Thus there suffered a total of 83.8% of patients on chronic venous insufficiency or peripheral arterial occlusive disease as a major factor in the genesis of the chronic leg ulcer. However, even the rarely diagnosed entities such as exogenous factors, vasculitis, pyoderma gangrenosum or infectious diseases are occur in summation in 16.2% of all patients and should therefore be known and excluded. In addition, the treatment periods and referral routes of patients with chronic leg ulcer should be identified. The analysis showed that the vast majority (86.8%) of patients with chronic ulcers who were investigated by us is treated by specialists. The treatment duration of general practitioners is 6.3 weeks (mean value) before the patient will be referred to a specialist. This treatment period is significantly shorter compared to the treatment period of the specialists, who treat their patients 14.1 weeks (mean value) before the patient will be referred to another specialist or to a clinic. Conclusion: Our results show the current aspects of aetiology and the way of treatment of patients with chronic leg ulcers in Germany.

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