scholarly journals The Clinical Significance of Circadian Rhythm and Blood Pressure Variability

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Rafidah Hanim Mokhtar ◽  
Maizatul Azma Masri ◽  
Hanis Hidayu Kasim ◽  
Azizi Ayob
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Blood Pressure Monitoring ◽  
Target Organ Damage ◽  
Circadian Variation ◽  
Biological Clock ◽  
Organ Damage ◽  
Time Of Day ◽  
Cardiac Events ◽  
Factors Affecting

— Sleep-wake cycle is the most evident 24 hour rhythms observed in humans. This circadian variation is a normal biological clock. The physiological phenomenon, however has been able to explain the onset of cardiac events that also tend to occur during certain time of day. It has been known that there is a tendency for major cardiovascular episodes to occur during the mid-morning hours. With the advent of ambulatory blood pressure monitoring, the fluctuations of blood pressure throughout the day are able to be captured. This is called blood pressure variability (BPV). The factors affecting BPV include age, sex, physical activity, mental activity, behavioural and environmental. Recent studies have shown that high BPV is associated with target organ damage, in particular cardiovascular and coronary artery diseases. In the effort to explain the mechanisms related to these complications out of excessive BPV, several studies explored the role of history of family with hypertension, hyperglycaemia and hyperlipidemia towards developing pre-existing condition that lead to high BPV.

scholarly journals THE PARTICULARITIES OF ABPM PARAMETERS IN HYPERTENSIVE PATIENTS WITH NON-DIALYSIS CKD

2017 ◽  
Vol 64 (4) ◽  
pp. 279-283
Author(s):  
Alexandru Minca ◽  
◽  
Mihai Comsa ◽  
Maria Mirabela Manea ◽  
Maria Daniela Tanasescu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Kidney Disease ◽  
Arterial Stiffness ◽  
Blood Pressure Monitoring ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Stiffness Index ◽  
Area Index ◽  
Hypertensive Patients ◽  
Arterial Stiffness Index

Chronic kidney disease (CKD) affects approximately two million people (in a population of 20 million) in Romania. Hypertension is often associated with CKD and both (hypertension and CKD) are risk factors for cardiovascular (CV) events. Ambulatory blood pressure monitoring (ABPM) is increasingly used all around the world for the diagnosis and monitoring of BP (blood pressure) because it is proven that the ABPM is superior to office BP measurements in evaluating patients with hypertension, with or without CKD. Reduced nocturnal BP fall (non-dipping or reverse-dipping patterns) is associated with target organ damage, especially kidney disease and the proportion of non-dippers and reverse-dippers patients increases progressively with the reduction of glomerular filtration rate (GFR). Another ABPM parameter, ambulatory arterial stiffness index (AASI), is an index which was recently proposed for the evaluation of arterial stiffness (a better tool than PP). It has prognostic value for cardiac death and stroke and several studies have showed that is negatively related to eGFR and is positively related to albuminuria. Hyperbaric area index (HBI) might be considered a novel sensitive marker [independent of patterns of NBPC (nocturnal BP change)] for the reduction of kidney function. These facts suggest that ABPM offers multiple useful data with impact, not only in future CV and renal outcomes assessment, but also in the treatment and management of hypertensive patients with CKD.

Correlation between blood pressure variability and subclinical target organ damage in patients with essential hypertension

2019 ◽  
Vol 34 (9) ◽  
pp. 641-647 ◽  
Author(s):  
Mostafa El Mokadem ◽  
Hesham Boshra ◽  
Yasser Abd el Hady ◽  
Amany Kasla ◽  
Ahmed Gouda
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Blood Pressure Variability ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ
Sign in / Sign up

Export Citation Format

Share Document