scholarly journals Rare Case of Chagas Disease

2021 ◽  
Vol 6 (12) ◽  
Keyword(s):  
Latin America ◽  
Sudden Death ◽  
Chagas Disease ◽  
Cardiac Failure ◽  
Rare Case ◽  
Correct Diagnosis ◽  
Extensive Investigation ◽  
Arrhythmogenic Cardiomyopathy ◽  
Multisystem Disease ◽  
Chronic Chagas Disease

Chagas is a multisystem disease transmitted from Trypanosoma cruiz, not uncommon in Latin America. This disease causes parasympathetic failure resulting in cardiac failure, arrhythmogenic, cardiomyopathy, sudden death, mega esophagus and mega colon. In this article, we present a case of chronic Chagas disease who had extensive investigation prior to reaching a correct diagnosis. We will highlight the symptomatology and treatment.

Sudden death caused by chronic Chagas disease in a non-endemic country: Autopsy report

2010 ◽  
Vol 60 (3) ◽  
pp. 235-240 ◽  
Author(s):  
Fumiko Satoh ◽  
Hiroshi Tachibana ◽  
Iwao Hasegawa ◽  
Motoki Osawa
Keyword(s):  
Sudden Death ◽  
Chagas Disease ◽  
Endemic Country ◽  
Autopsy Report ◽  
Chronic Chagas Disease

scholarly journals Translating Chagasic dilating cardiomyopathy to surgical therapies: An under published global challenge

2019 ◽  
Vol 7 ◽  
pp. 205031211989592
Author(s):  
Zoe C Groom ◽  
Vasileios Zochios ◽  
Aristotle D Protopapas
Keyword(s):  
Heart Failure ◽  
Latin America ◽  
Chagas Disease ◽  
Cardiac Failure ◽  
Economic Burden ◽  
Social Deprivation ◽  
Single System ◽  
Translational Model ◽  
Global Challenge ◽  
Autochthonous Transmission

Chagas disease is a neglected parasitic anthropozoonosis of the Americas linked to social deprivation with no hope of eradication in the future. Having been the most common non-ischemic cause of dilating cardiomyopathy in Latin America, it now spreads beyond the geographical boundaries of its vector via imported and autochthonous transmission. We review the evidence on surgery in Chagasic heart failure and offer a brief narrative on the main aspects of translational management. There is very limited literature on surgery for Chagasic heart failure, especially assist devices and transplantation. This may be attributed to the often unsurmountable economic burden of this single-system parasymphatholytic heart failure to young sufferers who commonly have very limited access to the aforementioned procedures. Chagasic heart failure offers a so far neglected translational model of parasymphatholytic non-ischemic cardiac failure.

A Rare Case of Tuberculous Prostatitis

2016 ◽  
Vol 1 (2) ◽  
pp. 33
Author(s):  
Nurul Yaqeen Mohd Esa ◽  
Mohammad Hanafiah ◽  
Marymol Koshy ◽  
Hilmi Abdullah ◽  
Ahmad Izuanuddin Ismail ◽  
...  
Keyword(s):  
Rare Case ◽  
Correct Diagnosis ◽  
Immunocompetent Patient ◽  
Clinical Suspicion ◽  
Tuberculosis Infection ◽  
Advanced Age ◽  
Immunocompromised Patients ◽  
Prostatic Biopsy ◽  
High Clinical Suspicion

Tuberculous prostatitis is an uncommon form of tuberculosis infection. It is commonly seen in immunocompromised patients and in those of middle or advanced age. The diagnosis is often not straight forward due to the nature of its presentation. We report a case of tuberculous prostatitis in a young, healthy and immunocompetent patient, who initially presented with respiratory features, followed by episodes of seizures and testicular swelling. He was finally diagnosed with tuberculous prostatitis after prostatic biopsy. This case illustrates that in a high TB prevalence environment, when symptoms warrant, there should be a high clinical suspicion coupled with a thorough approach in order to arrive at a correct diagnosis of TB prostatitis.

Effects of repetitive stress during the acute phase ofTrypanosoma cruziinfection on chronic Chagas' disease in rats

Stress ◽  
2009 ◽  
Vol 12 (2) ◽  
pp. 144-151 ◽  
Author(s):  
Leony Cristina Caetano ◽  
Vânia Brazão ◽  
Marina Del Vecchio Filipin ◽  
Fabricia Helena Santello ◽  
Luana Naiara Caetano ◽  
...  
Keyword(s):  
Chagas Disease ◽  
Acute Phase ◽  
Repetitive Stress ◽  
Chronic Chagas Disease

Ficolin‐3 in chronic Chagas disease: Low serum levels associated with the risk of cardiac insufficiency

2021 ◽  
Author(s):  
Kárita Cláudia Freitas Lidani ◽  
Fabiana Antunes Andrade ◽  
Marcia Holsbach Beltrame ◽  
Indira Chakravarti ◽  
Maria Regina Tizzot ◽  
...  
Keyword(s):  
Chagas Disease ◽  
Serum Levels ◽  
Cardiac Insufficiency ◽  
Chronic Chagas Disease ◽  
Low Serum

scholarly journals Neurochagas: A Rare Case of Reactivation of Chagas Disease after Heart Transplantation

2021 ◽  
Vol 40 (4) ◽  
pp. S485
Author(s):  
C.A. Aragao ◽  
I.W. Campos ◽  
R.T. Dantas ◽  
M.T. Lira ◽  
D.S. Belfort ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Chagas Disease ◽  
Rare Case

scholarly journals Serological Diagnosis of Chronic Chagas Disease: Is It Time for a Change?

2016 ◽  
Vol 54 (6) ◽  
pp. 1566-1572 ◽  
Author(s):  
Alba Abras ◽  
Montserrat Gállego ◽  
Teresa Llovet ◽  
Silvia Tebar ◽  
Mercedes Herrero ◽  
...  
Keyword(s):  
Chagas Disease ◽  
False Positive ◽  
Disease Diagnosis ◽  
Cross Reactivity ◽  
Human Migration ◽  
Serological Diagnosis ◽  
Content Type ◽  
New Generation ◽  
Single Technique ◽  
Chronic Chagas Disease

Chagas disease has spread to areas that are nonendemic for the disease with human migration. Since no single reference standard test is available, serological diagnosis of chronic Chagas disease requires at least two tests. New-generation techniques have significantly improved the accuracy of Chagas disease diagnosis by the use of a large mixture of recombinant antigens with different detection systems, such as chemiluminescence. The aim of the present study was to assess the overall accuracy of a new-generation kit, the Architect Chagas (cutoff, ≥1 sample relative light units/cutoff value [S/CO]), as a single technique for the diagnosis of chronic Chagas disease. The Architect Chagas showed a sensitivity of 100% (95% confidence interval [CI], 99.5 to 100%) and a specificity of 97.6% (95% CI, 95.2 to 99.9%). Five out of six false-positive serum samples were a consequence of cross-reactivity withLeishmaniaspp., and all of them achieved results of <5 S/CO. We propose the Architect Chagas as a single technique for screening in blood banks and for routine diagnosis in clinical laboratories. Only gray-zone and positive sera with a result of ≤6 S/CO would need to be confirmed by a second serological assay, thus avoiding false-positive sera and the problem of cross-reactivity withLeishmaniaspecies. The application of this proposal would result in important savings in the cost of Chagas disease diagnosis and therefore in the management and control of the disease.

scholarly journals Heart rate variability: Analysis of time-domain indices in patients with chronic Chagas disease before and after an exercise program

2013 ◽  
Vol 32 (3) ◽  
pp. 219-227 ◽  
Author(s):  
Marcus Vinicius Amaral da Silva Souza ◽  
Carla Cristiane Santos Soares ◽  
Juliana Rega de Oliveira ◽  
Cláudia Rosa de Oliveira ◽  
Paloma Hargreaves Fialho ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Chagas Disease ◽  
Time Domain ◽  
Exercise Program ◽  
Heart Rate Variability Analysis ◽  
Variability Analysis ◽  
Before And After ◽  
Chronic Chagas Disease

scholarly journals Evolution of anti-Trypanosoma cruzi antibody production in patients with chronic Chagas disease: Correlation between antibody titers and development of cardiac disease severity

2017 ◽  
Vol 11 (7) ◽  
pp. e0005796 ◽  
Author(s):  
Ingebourg Georg ◽  
Alejandro Marcel Hasslocher-Moreno ◽  
Sergio Salles Xavier ◽  
Marcelo Teixeira de Holanda ◽  
Eric Henrique Roma ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Disease Severity ◽  
Chagas Disease ◽  
Antibody Production ◽  
Cardiac Disease ◽  
Antibody Titers ◽  
Chronic Chagas Disease
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