scholarly journals The role of three-phase bone scintigraphy in arthroplasty of hip and knee joints of clean-up workers of Chornobyl accident

Author(s):  
M. Tkachenko ◽  
◽  
P. Korol ◽  
◽  
2018 ◽  
pp. 73-78
Author(s):  
P. Korol ◽  
M. Tkachenko

For 10 years, we studied the diagnostic role of three-phase bone scintigraphy (3-f BS) in the early prognosis of paraendoprosthetic complications in patients with degenerative-dystrophic and infectious-inflammatory diseases of the hip and knee joints. Using 3-f BS, the kinetic radionuclide parameters of inclusion and distribution of radiopharmaceutical (RP) in the projection of affected joints were evaluated. It was determined that the kinetics of osteotropic RP in the foci of fixation of affected joints in infectious and inflammatory processes is characterized by the predominance of retention and specific accumulation of the drug in the early and delayed static phase of 3-f BS in comparison with foci of fixing RP in degenerative-dystrophic lesions, which correlates with the differences destructively-reparative processes in them.According to the results of the analysis of the kinetic parameters, a radionuclide model of the dynamics of inclusion and distribution of RP in septic and aseptic joint lesions has been developed.


2018 ◽  
pp. 73-78
Author(s):  
P. Korol ◽  
M. Tkachenko

For 10 years, we studied the diagnostic role of three-phase bone scintigraphy (3-f BS) in the early prognosis of paraendoprosthetic complications in patients with degenerative-dystrophic and infectious-inflammatory diseases of the hip and knee joints. Using 3-f BS, the kinetic radionuclide parameters of inclusion and distribution of radiopharmaceutical (RP) in the projection of affected joints were evaluated. It was determined that the kinetics of osteotropic RP in the foci of fixation of affected joints in infectious and inflammatory processes is characterized by the predominance of retention and specific accumulation of the drug in the early and delayed static phase of 3-f BS in comparison with foci of fixing RP in degenerative-dystrophic lesions, which correlates with the differences destructively-reparative processes in them.According to the results of the analysis of the kinetic parameters, a radionuclide model of the dynamics of inclusion and distribution of RP in septic and aseptic joint lesions has been developed.


2017 ◽  
Vol 13 (1-2) ◽  
pp. 66-73
Author(s):  
М.М. Tkachenko ◽  
P.O. Korol

Relevance. The issue of degenerative-dystrophic lesions of the hip and knee joints is becoming urgent in Ukraine. To date, in order to visualize degenerative-dystrophic and infectious-inflammatory lesions in the treatment and diagnostic process, the three-phase bone scintigraphy method is actively used, with the help of which it is possible to obtain a quantitative characteristic of metabolic changes and the morphological status of the organism. Objective. To determine the specific radionuclide parameters of three-phase bone scintigraphy for optimizing the prediction of paraendoprosthetic complications in pathological lesions of hip and knee joints of different genesis. Material and methods. The retrospective analysis of 455 patients with diseases of hip and knee joints of various genesis (including 274 women and 181 men), aged from 17 to 85 years, was conducted in the work. All patients underwent three-phase bone scintigraphy according to the standard protocol. Results. In the early static phase of bone scintigraphy, a gradual increase in the percentage of inclusion and distribution of radiopharmaceutical in degenerative-dystrophic and infectious-inflammatory foci is observed. The increase in accumulation of the indicator in the delayed static phase in the infectious-inflammatory foci of deforming osteoarthrosis is caused by an increase in the intensity of blood flow in the angiographic phase, which indicated the intensification of the arterial blood supply of such foci, due to active inflammation, exposure to an infectious agent or increased osteoblastic activity. Conclusion. The determination of the kinetic parameters of bone scintigraphy and the application of the radionuclide model of «dual time point imaging» contribute to the early detection of paraendoprosthetic complications in the postoperative period, the reduction of the number of revision procedures and the reduction in the duration of rehabilitation and recovery measures after endoprosthetics.


2013 ◽  
Vol 34 (7) ◽  
pp. 638-644 ◽  
Author(s):  
Maria F. Villani ◽  
Piergiorgio Falappa ◽  
Milena Pizzoferro ◽  
Renato M. Toniolo ◽  
Antonio Lembo ◽  
...  

2013 ◽  
Vol 22 (3) ◽  
pp. 90-93 ◽  
Author(s):  
Zehra Pınar Koç ◽  
Tansel Ansal Balcı ◽  
M. Oğuzhan Özyurtkan

2021 ◽  
Vol 11 (6) ◽  
pp. 719
Author(s):  
Monika Toth ◽  
Anke Sambeth ◽  
Arjan Blokland

The processing of pre-experimentally unfamiliar stimuli such as abstract figures and non-words is poorly understood. Here, we considered the role of memory strength in the discrimination process of such stimuli using a three-phase old/new recognition memory paradigm. Memory strength was manipulated as a function of the levels of processing (deep vs. shallow) and repetition. Behavioral results were matched to brain responses using EEG. We found that correct identification of the new abstract figures and non-words was superior to old item recognition when they were merely studied without repetition, but not when they were semantically processed or drawn. EEG results indicated that successful new item identification was marked by a combination of the absence of familiarity (N400) and recollection (P600) for the studied figures. For both the abstract figures and the non-words, the parietal P600 was found to differentiate between the old and new items (late old/new effects). The present study extends current knowledge on the processing of pre-experimentally unfamiliar figurative and verbal stimuli by showing that their discrimination depends on experimentally induced memory strength and that the underlying brain processes differ. Nevertheless, the P600, similar to pre-experimentally familiar figures and words, likely reflects improved recognition memory of meaningless pictorial and verbal items.


2021 ◽  
Vol 30 (2) ◽  
pp. 106-116
Author(s):  
Abira Reizer ◽  
Meni Koslowsky ◽  
Rivki Antilevich-Steg

In recent years, several investigations of the medical clowning profession have appeared in the literature. However, few studies have focused on factors associated with turnover among medical clowns early in their careers. The current study examined whether individual differences in humor disposition predicted turnover behavior. Participants were 111 medical clowns in a three-phase longitudinal study. Humor disposition was measured in the first week of their training, clowns' job satisfaction two months later, and turnover six months after that. Results showed that humor appreciation decreased actual turnover through the mediating role of job satisfaction, whereas individual differences in humor creation directly decreased turnover. In addition, previous traumatic experiences moderated the associations between humor appreciation and turnover. Overall, our research findings support the notion that humor disposition can help predict which clowns remain in the hospital.


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