Selenium supplementation for the reduction of thyroid antibodies in Hashimoto’s thyroiditis patients: a systematic review

Author(s):  
Mikaila Beaver ◽  
Bradley Leech
2013 ◽  
Vol 3 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Esther J. van Zuuren ◽  
Amira Y. Albusta ◽  
Zbys Fedorowicz ◽  
Ben Carter ◽  
Hanno Pijl

Thyroid ◽  
2010 ◽  
Vol 20 (10) ◽  
pp. 1163-1173 ◽  
Author(s):  
Konstantinos A. Toulis ◽  
Athanasios D. Anastasilakis ◽  
Thrasivoulos G. Tzellos ◽  
Dimitrios G. Goulis ◽  
Dimitrios Kouvelas

2011 ◽  
Vol 55 (8) ◽  
pp. 628-631 ◽  
Author(s):  
Claudia Dutra Costantin Faria ◽  
Simone Ribeiro ◽  
Cristiane Kochi ◽  
Aryane Pereira Neves da Silva ◽  
Bruna Natalia Freire Ribeiro ◽  
...  

INTRODUCTION: Patients with Down syndrome (DS) often have elevated TSH (hypothalamic origin), which is called TSH neurosecretory dysfunction (TSH-nd). In these cases, there is slight elevation in TSH (5-15 µUI/mL), with normal free T4 and negative thyroid antibodies (AB). OBJECTIVE: To recognize the risk of progression to Hashimoto's thyroiditis (HT). SUBJECTS AND METHODS: We retrospectively analyzed 40 DS patients (mean age = 4.5 years), followed up for 6.8 years. RESULTS: HT was diagnosed in 9/40 patients, three early in monitoring, and six during evolution. In 31/40 patients, TSH-nd diagnosis remained unchanged over the years, with maximum TSH values ranging from 5 to 15 µUI/mL. In this group, free T4 also remained normal and AB were negative. There was a significant TSH reduction (p = 0.017), and normal TSH concentrations (< 5.0 µUI/mL) were observed in 29/31 patients, in at least one moment. No patient had TSH > 15 µUI/mL. CONCLUSION: DS patients with TSH-nd present low risk of progression to HT (10% for females and 6% for males).


1968 ◽  
Vol 13 (1) ◽  
pp. 13-16 ◽  
Author(s):  
J. A. Thomson ◽  
I. M. D. Jackson ◽  
W. P. Duguid

A patient is described who passed from a clinical state consistent with Hashimoto's thyroiditis to Riedel's thyroiditis over a period of 6 months. Serum levels of thyroid antibodies were high and there was a family history of Hashimoto's thyroiditis. A good therapeutic response to steroids was observed but these were without effect in a further patient with Riedel's thyroiditis of 10 years' duration. It is suggested that Riedel's thyroiditis is an uncommon variant of Hashimoto's thyroiditis.


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