scholarly journals Anaesthesia for Live Related Liver Transplantation: Experience at a Teaching Hospital in Abroad

1970 ◽  
Vol 39 (3) ◽  
Author(s):  
K Sadar ◽  
MA Hannan ◽  
S Aneja
Keyword(s):  
Liver Transplantation ◽  
Therapeutic Option ◽  
Service Availability ◽  
Invasive Monitoring ◽  
Blood Products ◽  
Chronic Liver Failure ◽  
Laboratory Service ◽  
Non Invasive ◽  
Apollo Hospital ◽  
Liver Transplantations

ordinary, challenging and very much special for anaesthesiologists. The liver transplantation programme at Indraprastha Apollo Hospital, Delhi, India has been running since 1998. Both live related and cadveric liver transplantations are performed and it is about 100 to 120 per year. In this prospective study, the anaesthetic aspects of 10 live related liver transplantations are reviewed. Here we focused on anaesthetic technique used; indications for liver transplantation and type of graft transplanted; survival rate; duration of anaesthesia and cost; intra-operativeLive related liver transplantation is no longer experimental. It is the therapeutic option for patients with chronic liver failure. Adequate logistic and prompt laboratory service, availability of blood products, maximum invasive and non invasive monitoring is mandatory for better outcome.BMJ 2010; 39(3)

scholarly journals New Indications for Liver Transplantation

2021 ◽  
Vol 10 (17) ◽  
pp. 3867
Author(s):  
Alberto Zanetto ◽  
Sarah Shalaby ◽  
Martina Gambato ◽  
Giacomo Germani ◽  
Marco Senzolo ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Transplant Patient ◽  
Patient Survival ◽  
Therapeutic Option ◽  
Chronic Liver Failure ◽  
Exclusion Criteria ◽  
Cancer Metastases ◽  
Colorectal Cancer Metastases ◽  
Clinical Conditions

Liver transplantation (LT) is an important therapeutic option for the treatment of several liver diseases. Modern LT is characterized by remarkable improvements in post-transplant patient survival, graft survival, and quality of life. Thanks to these great improvements, indications for LT are expanding. Nowadays, clinical conditions historically considered exclusion criteria for LT, have been considered new indications for LT, showing survival advantages for patients. In this review, we provide an updated overview of the principal newer indications for LT, with particular attention to alcoholic hepatitis, acute-on-chronic liver failure (ACLF), cholangiocarcinoma and colorectal cancer metastases.

Adult-to-Adult Living-Donor Liver Transplantation

Swiss Surgery ◽  
2003 ◽  
Vol 9 (5) ◽  
pp. 227-236 ◽  
Author(s):  
Majno ◽  
Mentha ◽  
Berney ◽  
Bühler ◽  
Giostra ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Therapeutic Option ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Multidisciplinary Program ◽  
First Case ◽  
Living Donor Transplantation ◽  
The Right

Living donor liver transplantation is a relatively new procedure in which the right side of the liver is harvested in a healthy donor and transplanted into a recipient. After the first case in 1994, over 3000 cases have been done worldwide. This review summarizes the reasons why the procedure is needed, describes its main technical aspects, highlights the boundaries in which it can be done safely, summarizes the current experience worldwide and describes the main points of the program in our unit. We argue that living-donor transplantation is a viable alternative to a long time on the waiting list for several patients, and it can be performed safely and successfully provided that all precautions are undertaken to minimize the risks in the donor and to increase the chances of a good outcome in the recipients. If these prerequisites are met, and within the framework of a structured multidisciplinary program, we believe that living-donor liver transplantation should be funded by health insurances as a recognized therapeutic option.

The Need for Consensus About Liver Transplantation For Patients With Neuropsychiatric Wilson’s Disease

2021 ◽  
pp. 152692482110028
Author(s):  
Alberto Ferrarese ◽  
Patrizia Burra
Keyword(s):  
Liver Transplantation ◽  
Patient Outcomes ◽  
Wilson’S Disease ◽  
Therapeutic Option ◽  
Copper Metabolism ◽  
Wilson's Disease ◽  
Published Data ◽  
Neurological Improvement ◽  
Effective Therapeutic Option

Liver transplantation is considered an effective therapeutic option for Wilson’s disease (WD) patients with hepatic phenotype, since it removes the inherited defects of copper metabolism, and is associated with excellent graft and patient outcomes. The role of liver transplantation in WD patients with mixed hepatic and neuropsychiatric phenotype has remained controversial over time, mainly because of high post-operative complications, reduced survival and a variable, unpredictable rate of neurological improvement. This article critically discusses the recently published data in this field, focussing in more detail on isolated neuropsychiatric phenotype as a potential indication for liver transplantation in WD patients.

scholarly journals Methodology: non-invasive monitoring system based on standing wave ratio for detecting water content variations in plants

Plant Methods ◽  
2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Yunjeong Yang ◽  
Ji Eun Kim ◽  
Hak Jin Song ◽  
Eun Bin Lee ◽  
Yong-Keun Choi ◽  
...  
Keyword(s):  
Water Content ◽  
Monitoring System ◽  
Standing Wave ◽  
Magnetic Particles ◽  
Experimental Plant ◽  
Invasive Monitoring ◽  
Monitoring Method ◽  
Non Invasive ◽  
Content Variation ◽  
Stem Water

Abstract Background Water content variation during plant growth is one of the most important monitoring parameters in plant studies. Conventional parameters (such as dry weight) are unreliable; thus, the development of rapid, accurate methods that will allow the monitoring of water content variation in live plants is necessary. In this study, we aimed to develop a non-invasive, radiofrequency-based monitoring system to rapidly and accurately detect water content variation in live plants. The changes in standing wave ratio (SWR) caused by the presence of stem water and magnetic particles in the stem water flow were used as the basis of plant monitoring systems. Results The SWR of a coil probe was used to develop a non-invasive monitoring system to detect water content variation in live plants. When water was added to the live experimental plants with or without illumination under drought conditions, noticeable SWR changes at various frequencies were observed. When a fixed frequency (1.611 GHz) was applied to a single experimental plant (Radermachera sinica), a more comprehensive monitoring, such as water content variation within the plant and the effect of illumination on water content, was achieved. Conclusions Our study demonstrated that the SWR of a coil probe could be used as a real-time, non-invasive, non-destructive parameter for detecting water content variation and practical vital activity in live plants. Our non-invasive monitoring method based on SWR may also be applied to various plant studies.

How we treat sickle hepatopathy and liver transplantation in adults

Blood ◽  
2014 ◽  
Vol 123 (15) ◽  
pp. 2302-2307 ◽  
Author(s):  
Kate Gardner ◽  
Abid Suddle ◽  
Pauline Kane ◽  
John O’Grady ◽  
Nigel Heaton ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Sickle Cell ◽  
Liver Dysfunction ◽  
Therapeutic Option ◽  
Organ Damage ◽  
Treatment Modalities ◽  
Cell Disease ◽  
Limited Evidence ◽  
Acute Form ◽  
Future Work

Abstract Sickle cell disease (SCD) has evolved into a debilitating disorder with emerging end-organ damage. One of the organs affected is the liver, causing “sickle hepatopathy,” an umbrella term for a variety of acute and chronic pathologies. Prevalence of liver dysfunction in SCD is unknown, with estimates of 10%. Dominant etiologies include gallstones, hepatic sequestration, viral hepatitis, and sickle cell intrahepatic cholestasis (SCIC). In addition, causes of liver disease outside SCD must be identified and managed. SCIC is an uncommon, severe subtype, with outcome of its acute form having vastly improved with exchange blood transfusion (EBT). In its chronic form, there is limited evidence for EBT programs as a therapeutic option. Liver transplantation may have a role in a subset of patients with minimal SCD-related other organ damage. In the transplantation setting, EBT is important to maintain a low hemoglobin S fraction peri- and posttransplantation. Liver dysfunction in SCD is likely to escalate as life span increases and patients incur incremental transfusional iron overload. Future work must concentrate on not only investigating the underlying pathogenesis, but also identifying in whom and when to intervene with the 2 treatment modalities available: EBT and liver transplantation.

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