scholarly journals Study on Primary Percutaneous Coronary Intervention (PCI) in Patient with Acute Myocardial Infarction: In-Hospital and 30-days Survival Outcome

1970 ◽  
Vol 2 (2) ◽  
pp. 212-217 ◽  
Author(s):  
AQM Reza ◽  
AHMW Islam ◽  
S Munwar ◽  
S Talukder
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Hospital Setting ◽  
Coronary Intervention ◽  
Anterior Wall ◽  
Survival Outcome ◽  
Drug Eluting Stent ◽  
Primary Pci ◽  
Catheterization Laboratory ◽  
Cardiac Catheterization Laboratory

Objective: Aim of our study was to evaluate the safety and survival outcome of Primary PCI (pPCI) in patients with Acute Myocardial infarction in our hospital setting. Methods: Total 30 (Female 5; Male 25) patients were enrolled in this study who were brought in to our hospital with STEMI. Average age was, Male 56, Female 52. Primary PCI was performed after transferring patient from Emergency Department (ED) to Cardiac Catheterization laboratory. Cardiovascular risk factors among the studied population were Dyslipidemia, Diabetes Mellitus, Hypertension, Smoking and Family History. Results: Primary PCI either with Bare Metal Stent (BMS) or Drug Eluting Stent (Sirolimus-eluting stent or Paclitaxel stent) were performed in total 13 LAD lesion and 15 RCA lesion and 2 LCX lesion. BMS used were 66.7%, Sirolimus 20% and Paclitaxel-eluting stent 13.3%. Total 2 patients expired but due to hemorrhagic CVA and refractory heart failure. At presentation, ECG evidenced diagnosis were Acute Anterior Wall MI : 12 (40%), Inferior MI: 16 (53%), Infero-Posterior MI: 2 (6.7%). Our study showed that Primary PCI increases the higher survival outcome 28 (93.3%) out of 30 patients with acute MI. Conclusion: Our present study revealed that revascularization by Primary PCI showed safety and better percentage of In-hospital and 30-days survival outcome in patients with Acute myocardial infarction in our hospital setting. Keywords: Primary PCI; STEMI. DOI: 10.3329/cardio.v2i2.6641Cardiovasc. j. 2010; 2(2) : 212-217

scholarly journals Outcomes of primary percutaneous coronary intervention (PCI) in NICVD, Dhaka,Bangladesh- our initial experiences

2015 ◽  
Vol 9 (2) ◽  
pp. 83-87 ◽  
Author(s):  
Mir Jamaluddin ◽  
Ibrahim Khalil ◽  
Kajal Kumar Karmakar ◽  
Humayun Kabir ◽  
Rakibul Islam Litu ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Primary Percutaneous Coronary Intervention ◽  
Positive Family History ◽  
Coronary Intervention ◽  
Bare Metal Stent ◽  
Drug Eluting Stent ◽  
Primary Pci ◽  
Catheterization Laboratory ◽  
Cardiac Catheterization Laboratory ◽  
Percutaneous Coronary

The aim of the study is to determine the out comes of primary percutaneous coronary intervention (PCI) in patients with acute myocardial infarction in NICVD the only government cardiac hospital of Bangladesh where resources are very limited. Total 73 (male 70, female 3) patients were enrolled in this study who were brought in to our hospital with STEMI between August 2010 to October 2013. Average age was 55.6 ±11.78. Primary PCI was performed after transferring patient from Emergency Department to cardiac catheterization laboratory. Cardiovascular risk factors among the studied population were Diabetes mellitus, Hypertension, Smoking, Dyslipidemia and Positive family history for IHD. Primary PCI either with Bare Metal Stent (BMS) or Drug Eluting Stent (DES) were performed in total 42 LAD lesions, 28 RCA lesions and 3 LCX lesions. BMS used were 87.7%, DES used were 12.3%. The procedural success was 95.8%.Four patients (5.4%) died during hospital stay. Out of four patients who died, one had cardiogenic shock. No mortality was observed in the 30 days follow up from discharge, while other complications like unstable angina and congestive heart failure were 5.7% and 4.3% respectively. Our findings suggest favorable outcomes, matching the international data which was achieved in our patients with primary PCI in the management of STEMI despite all the limitations. Primary PCI as a preferred method of reperfusion strategy needs to be practiced more often in our part of world.University Heart Journal Vol. 9, No. 2, July 2013; 83-87

scholarly journals Case Report of the Patient with Acute Myocardial Infarction: “From Flatline to Stent Implantation”

2017 ◽  
Vol 34 (4) ◽  
pp. 329-337
Author(s):  
Dejan Petrović ◽  
Marina Deljanin Ilić ◽  
Bojan Ilić ◽  
Sanja Stojanović ◽  
Milovan Stojanović ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiac Arrest ◽  
Lung Tumor ◽  
Early Recognition ◽  
Coronary Intervention ◽  
Anterior Wall ◽  
Severe Form ◽  
St Segment Elevation ◽  
Catheterization Laboratory

Summary Asystole is a rare primary manifestation in the development of sudden cardiac death (SCD), and survival during cardiac arrest as the consequence of asystole is extremely low. The aim of our paper is to illustrate successful cardiopulmonary resuscitation (CPR) in patients with acute myocardial infarction (AMI) and rare and severe form of cardiac arrest - asystole. A very short time between cardiac arrest in acute myocardial infarction, which was manifested by asystole, and the adequate CPR measures that have been taken are of great importance for the survival of our patient. After successful reanimation, the diagnosis of anterior wall AMI with ST segment elevation was established. The right therapeutic strategy is certainly the early primary percutaneous coronary intervention (PPCI). In less than two hours, after recording the “flatline” and successful reanimation, the patient was in the catheterization laboratory, where a successful PPCI of LAD was performed, after emergency coronary angiography. In the further treatment course of the patient, the majority of risk factors were corrected, except for smoking, which may be the reason for newly discovered lung tumor disease. Early recognition and properly applied treatment of CPR can produce higher rates of survival.

Thrombolytic Therapy in the Current ERA: Myocardial Infarction and Beyond

2018 ◽  
Vol 24 (4) ◽  
pp. 414-426 ◽  
Author(s):  
Patrick Proctor ◽  
Massoud A. Leesar ◽  
Arka Chatterjee
Keyword(s):  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Acute Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Ischemic Stroke ◽  
Thrombolytic Therapy ◽  
Coronary Intervention ◽  
Evidence Base ◽  
Primary Pci ◽  
Percutaneous Coronary

Thrombolytic therapy kick-started the era of modern cardiology but in the last few decades it has been largely supplanted by primary percutaneous coronary intervention (PCI) as the go-to treatment for acute myocardial infarction. However, these agents remain important for vast populations without access to primary PCI and acute ischemic stroke. More innovative uses have recently come up for the treatment of a variety of conditions. This article summarizes the history, evidence base and current use of thrombolytics in cardiovascular disease.

Abstract 2832: Which Cardiac Marker is Most Useful to Predict Final Infarct Size and Cardiac Function Following Primary Percutaneous Coronary Intervention For Acute Myocardial Infarction?

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Stanley Chia ◽  
O. Christopher Raffel ◽  
Faisal Merchant ◽  
Frans J Wackers ◽  
Fred Senatore ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Infarct Size ◽  
Troponin I ◽  
Troponin T ◽  
Coronary Intervention ◽  
Left Ventricular ◽  
Cardiac Biomarkers ◽  
Primary Pci ◽  
Percutaneous Coronary

Background: Assessment of cardiac biomarker release has been traditionally used to estimate the size of myocardial damage after acute myocardial infarction (AMI). However, the significance of cardiac biomarkers in the setting of primary percutaneous coronary intervention (PCI) has not been systematically studied in a large patient cohort. We evaluated the usefulness of serial and single time-point measures of various cardiac biomarkers (creatine kinase (CK), CK-MB, troponin T and I) in predicting infarct size and left ventricular ejection fraction (LVEF) after primary PCI. Methods: EVOLVE (Evaluation of MCC-135 for Left Ventricular Salvage in AMI) was a randomized double-blind, placebo-controlled trial comparing the efficacy of intracellular calcium modulator as an adjunct to primary PCI in patients with first large AMI. Levels of cardiac biomarkers (CK, CK-MB mass, troponin T and I) were determined in 375 patients at baseline before PCI and 2, 4, 12, 24, 48 and 72 hours thereafter. Single photon emission computed tomography imaging was performed to measure infarct size and LVEF on day 5. Results: Area under curve and peak concentrations of all cardiac markers: CK, CK-MB mass, troponin T and troponin I were significantly correlated with myocardial infarct size and LVEF determined on day 5 (Spearman correlation, all P< 0.001; Table ). Troponin I, however provided the best predictor and a single measure at 72 hr was a strong indicator of both infarct size and LVEF. Using receiver operator characteristics curve, troponin I cutoff value of >55 pg/mL at 72 hr has 90% sensitivity and 70% specificity for detection of large infarct size≥10% ( c =0.88; P< 0.001). Conclusions: Plasma levels of CK, CK-MB, troponin T and troponin I remain useful predictors of infarct size and cardiac function in the era of primary PCI for AMI. A single measurement of circulating troponin I at 72 hours can provide an effective and convenient indicator of infarct size and LVEF in clinical practice. Correlation of cardiac biomarkers with Day 5 SPECT determined infarct size and LVEF

scholarly journals Effect of primary percutaneous coronary intervention on ventricular repolarization through evaluation of QT dispersion in patient with acute myocardial infarction

2018 ◽  
Vol 5 (2) ◽  
pp. 506
Author(s):  
Behzad Babapour ◽  
Bita Shahbazzadegan ◽  
Bahareh Khademi
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Ventricular Arrhythmia ◽  
Primary Percutaneous Coronary Intervention ◽  
Qt Dispersion ◽  
Coronary Intervention ◽  
Ventricular Repolarization ◽  
Primary Pci ◽  
Percutaneous Coronary

Background: Cardiovascular disease is the most common cause of death around the world. QT dispersion is one of the parameters that used for evaluation of ventricular arrhythmia. Primary PCI increases probability of coronary artery and reperfusion of the ventricular arrhythmia. The aim of this study was to determine effect of primary percutaneous coronary intervention (PCI) on ventricular repolarization through evaluation of QT dispersion in patient with acute myocardial infarction. Methods: In this pre-post test study, 77 patients with acute ST with elevated myocardial infarction under primary PCI were investigated. The ECG and ST dispersion before PCI and 24 hours after PCI were determined and then the amount of QTd was calculated. The repeated measurement ANOVA was used to compare QTd of pre- PCI treatment and QTd in 24 hours after PCI. Data analysis was performed using statistical software SPSS ver.17. Results: From 77 participants, 60 were male and 17 were female. 43 (55.8%) had a MI position in ANT, PRE, and EXT, 33 (42.9%) had in the INF, and only one person (1.3%) had a MI position in LAT. The results showed that mean QT dispersion in ECG, 24h after primary PCI, for most of measured variables was deceased compare to before primary PCI, but the difference was not significant. Conclusions: The amount of QTd 24 hours after PCI decreased but its decline was not significant. With regards to lack of convenience data, more researches are recommended in this field. 

Abstract 1999: Percutaneous Coronary Intervention with Off-site Cardiac Surgery Backup for Acute Myocardial Infarction as a Strategy to Reduce Door-to-Balloon Time.

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Victor A Umans ◽  
Hans O Peels ◽  
Hans de Swart ◽  
Raymond Hautvast
Keyword(s):  
Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Cardiac Surgery ◽  
Community Hospital ◽  
Hospital Setting ◽  
Coronary Intervention ◽  
Primary Pci ◽  
Percutaneous Coronary ◽  
Tertiary Center ◽  
Door To Balloon

We sought to determine whether primary percutaneous coronary intervention (PCI) for patients admitted with an acute ST-segment elevation myocardial infarction (STEMI) can be performed more rapidly and with comparable outcomes in a community hospital vs. a tertiary center with cardiac surgery. We started the first PCI with off-site surgery program in the Netherlands in 2002 and report the results of 639 consecutive pts. In the safety phase, 199 patients presenting with STEMI were randomly assigned to treatment at our off-site center vs a more distant cardiac surgery center. In the confirmation phase, 440 consecutive patients were treated in the off-site hospital. Safety and efficacy endpoints were the rate of angiographically successful PCI procedure (diameter stenosis <50% and TIMI 3 flow) in the absence of major adverse cardiac and cerebrovascular events (MACCE) at 30 days. The randomization phase showed a significant decrease of 37 minutes in door-to-balloon time (p<0.001) with comparable procedural and clinical success (91% TIMI-3 flow in both groups). In the confirmation phase, the 30-day MACCE-free rate was 95%. None of the 639 patients in the study required emergency surgery for failed primary PCI. Time to treatment with primary PCI can be significantly reduced when treating patients in a community hospital setting with off-site cardiac surgery backup as compared with transport for PCI to a referral center with on-site surgery. PCI at hospitals with off-site cardiac surgery backup can be considered as one of the needed strategies to improve access to primary PCI for a larger segment of the population basis, and can be delivered with a very favorable safety profile.

Sign in / Sign up

Export Citation Format

Share Document