Safety, Efficacy and Indications of ?-Blockers to Reduce Heart Rate prior to Coronary CT Angiography-An Overview

2012 ◽  
Vol 5 (1) ◽  
pp. 100-106
Author(s):  
WA Jahan ◽  
A Azam ◽  
S Deena ◽  
W Begum ◽  
M Rahman

For selected indications, coronary computed tomographic (CT) angiography is an established clinical technology for evaluation in patients suspected of having or known to have coronary artery disease. In coronary CT angiography, image quality is highly dependent on heart rate, with heart rate reduction to less than 60 beats per minute being important for both image quality and radiation dose reduction, especially when single-source CT scanners are used. â-Blockers are the first-line option for short-term reduction of heart rate prior to coronary CT angiography. In recent years, multiple âblocker administration protocols with oral and/or intravenous application have been proposed.This review article provides an overview of the indications, efficacy, and safety of â-blockade protocols prior to coronary CT angiography with respect to different scanner techniques. Moreover,implications for radiation exposure and left ventricular function analysis are discussed DOI: http://dx.doi.org/10.3329/cardio.v5i1.12280 Cardiovasc. j. 2012; 5(1): 100-106

2018 ◽  
Vol 28 (10) ◽  
pp. 1148-1153 ◽  
Author(s):  
Hirofumi Watanabe ◽  
Hiroshi Kamiyama ◽  
Masataka Kato ◽  
Akiko Komori ◽  
Yuriko Abe ◽  
...  

AbstractBackgroundThere is no standard dose or protocol for beta-blocker administration as preconditioning in children undergoing coronary CT angiography.MethodsA total of 63 consecutive patients, with a mean age of 10.0±3.1 years, who underwent coronary CT angiography to assess possible coronary complications were enrolled in a single-centre, retrospective study. All patients were given an oral beta-blocker 1 hour before coronary CT angiography. Additional oral beta-blocker or intravenous beta-blocker was given to those with a high heart rate. We compared image quality, radiation exposure, and adverse events among the patients without additional beta-blocker, with additional oral beta-blocker, and with additional intravenous beta-blocker.ResultsThere were no significant differences in image quality or radiation exposure among the groups. The heart rate just before scanning was significantly correlated with image quality (p<0.001, r=−0.533) but was not correlated with radiation exposure (p=0.45, r=0.096). There were no adverse events related to any allergic reaction, thereby showing the effectiveness of the beta-blocker.ConclusionInitial oral beta-blocker administration (0.8 mg/kg/dose) should be administered to all children undergoing coronary CT angiography. Additional intravenous beta-blocker should be given to those with poor heart rate control to improve image quality without increasing radiation exposure or allowing adverse events.


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pp. 614-623 ◽  
Author(s):  
Amir A. Mahabadi ◽  
Stephan Achenbach ◽  
Christof Burgstahler ◽  
Thorsten Dill ◽  
Roman Fischbach ◽  
...  

Radiology ◽  
2008 ◽  
Vol 248 (3) ◽  
pp. 792-798 ◽  
Author(s):  
Annick C. Weustink ◽  
Nico R. Mollet ◽  
Francesca Pugliese ◽  
Willem B. Meijboom ◽  
Koen Nieman ◽  
...  

Radiology ◽  
2021 ◽  
pp. 210245
Author(s):  
Thomas J. Stocker ◽  
Jonathon Leipsic ◽  
Marcus Y. Chen ◽  
Stephan Achenbach ◽  
Juhani Knuuti ◽  
...  

2011 ◽  
Vol 21 (11) ◽  
pp. 2277-2284 ◽  
Author(s):  
D. Muenzel ◽  
P. B. Noel ◽  
F. Dorn ◽  
M. Dobritz ◽  
E. J. Rummeny ◽  
...  

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