scholarly journals Management of anthracnose and blight diseases of Houttuynia cordata Thunb. with fungicides

2015 ◽  
Vol 39 (1) ◽  
pp. 83-90
Author(s):  
Shamim Shamsi ◽  
Trisha Saha
Keyword(s):  
Colletotrichum Gloeosporioides ◽  
Pathogenic Fungi ◽  
Efficient Inhibitor ◽  
Houttuynia Cordata ◽  
In Vivo Treatment ◽  
Houttuynia Cordata Thunb ◽  
Academy Of Sciences

Two types of symptoms, namely anthracnose and blight were recorded on Houttuynia cordata Thunb. during the period of April to December 2013. The isolated fungi from the diseased plants were Alterneria alternata (Fr.) Keissler and Colletotrichum gloeosporioides (Penz.) Sacc. Five fungicides viz., Bavistin DF, Dithane M-45, Indofil, Salcox 50 WP and Tall 25 EC were evaluated against the pathogenic fungi at 100, 200, 300, 400 and 500 ppm concentrations. Tall 25 EC was found most efficient inhibitor of the test fungi followed by Bavistin, Indofil, Dithane M-45 and Salcox. In vivo treatment Tall 25 EC was found most effective in controlling the diseases.Journal of Bangladesh Academy of Sciences, Vol. 39, No. 1, 83-90, 2015

scholarly journals Effects of botanicals against anthracnose and blight diseases of Houttuynia cordata Thunb

2016 ◽  
Vol 42 (1) ◽  
pp. 41-48
Author(s):  
Trisha Saha ◽  
Shamim Shamsi
Keyword(s):  
Azadirachta Indica ◽  
Pathogenic Fungi ◽  
Tagetes Erecta ◽  
Citrus Limon ◽  
Leaf Extracts ◽  
Houttuynia Cordata ◽  
Datura Metel ◽  
Houttuynia Cordata Thunb

Anthracnose and blight were recorded on Houttuynia cordata Thunb. during April 2013 to December 2013. The isolated fungi from the symptomatic plants were identified as Alterneria alternata (Fr.) Keissler and Colletotrichum gloeosporoides (Penz.) Sacc. Ethanol leaf extracts of five plants viz.,Azadirachta indica L., Citrus limon L., Datura metel L., Sennaalata L. and Tagetes erecta L.were evaluated against the pathogenic fungi A. alternata and C. gloeosporoides at 5%, 10% and 20% concentrations in vitro. A. indica recorded as good inhibitor against the test fungi followed by C. limon, S. alata, D. metel and T.erecta. In vivo treatment also showed that A.indica is the most effective in controlling diseases at 10% concentration. The plants treated with A. indica were fresh and healthy up to one month of observation.J. Asiat. Soc. Bangladesh, Sci. 42(1): 41-48, June 2016

scholarly journals Latent Pathogenic Fungi in the Medicinal Plant Houttuynia cordata Thunb. Are Modulated by Secondary Metabolites and Colonizing Microbiota Originating from Soil

2021 ◽  
Vol 70 (3) ◽  
pp. 359-372
Author(s):  
HAI-TAO YE ◽  
SHI-QIONG LUO ◽  
ZHAN-NAN YANG ◽  
YUAN-SHUAI WANG ◽  
QIAN DING
Keyword(s):  
Secondary Metabolites ◽  
Pathogenic Fungi ◽  
Penicillium Citrinum ◽  
Sterile Soil ◽  
Mutual Inhibition ◽  
Houttuynia Cordata ◽  
Negative Effect ◽  
Houttuynia Cordata Thunb ◽  
In Vitro Antifungal Activity

Latent pathogenic fungi (LPFs) affect plant growth, but some of them may stably colonize plants. LPFs were isolated from healthy Houttuynia cordata rhizomes to reveal this mechanism and identified as Ilyonectria liriodendri, an unidentified fungal sp., and Penicillium citrinum. Sterile H. cordata seedlings were cultivated in sterile or non-sterile soils and inoculated with the LPFs, followed by the plants’ analysis. The in vitro antifungal activity of H. cordata rhizome crude extracts on LPF were determined. The effect of inoculation of sterile seedlings by LPFs on the concentrations of rhizome phenolics was evaluated. The rates of in vitro growth inhibition amongst LPFs were determined. The LPFs had a strong negative effect on H. cordata in sterile soil; microbiota in non-sterile soil eliminated such influence. There was an interactive inhibition among LPFs; the secondary metabolites also regulated their colonization in H. cordata rhizomes. LPFs changed the accumulation of phenolics in H. cordata. The results provide that colonization of LPFs in rhizomes was regulated by the colonizing microbiota of H. cordata, the secondary metabolites in the H. cordata rhizomes, and the mutual inhibition and competition between the different latent pathogens.

scholarly journals Identification and pathogenic potentiality of fungi associated with Houttuynia cordata thunb.

1970 ◽  
Vol 20 (2) ◽  
pp. 131-138
Author(s):  
Rumana Azad ◽  
Shamim Shamsi
Keyword(s):  
Aspergillus Niger ◽  
Aspergillus Flavus ◽  
New Record ◽  
Colletotrichum Gloeosporioides ◽  
Trichoderma Viride ◽  
Houttuynia Cordata ◽  
Colletotrichum Dematium ◽  
Fusarium Sp ◽  
Colletotrichum Coffeanum ◽  
Houttuynia Cordata Thunb

A total of 17 species of fungi representing 11 genera were found to be associated with Houttuynia cordata Thunb. The isolated fungi were Aspergillus flavus Link, Aspergillus niger Van Tiegh., Cercospora houtttuyniicola Goh et Hsieh, Colletotrichum coffeanum Noack, Colletotrichum dematium (Pers. Ex Fr.) Grove, Colletotrichum gloeosporioides (Penz.) Sacc., Curvularia brachyspora Boedijn., Curvularia fallax Boedijn., Curvularia pallescens Boedijn., Fusarium sp., Nigrospora sacchari (Speg.) Mason., Penicillium sp., Pestalotiopsis spp., Syncephalastrum sp., Trichoderma viride Pers. Ex Fries. and a member of Zygomycetes. Cercospora houtttuyniicola is a new record for Bangladesh. All the isolated fungi were tested for pathogenicity. Key words: Fungi; Association; Houttuynia cordata; Pathogenic potentiality DOI: http://dx.doi.org/10.3329/dujbs.v20i2.8973 DUJBS 2011; 20(2): 131-138

scholarly journals Suppressive Effect and Molecular Mechanism of Houttuynia cordata Thunb. Extract against Prostate Carcinogenesis and Castration-Resistant Prostate Cancer

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3403
Author(s):  
Subhawat Subhawa ◽  
Aya Naiki-Ito ◽  
Hiroyuki Kato ◽  
Taku Naiki ◽  
Masayuki Komura ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Castration Resistant Prostate Cancer ◽  
Lncap Cells ◽  
In Vivo Models ◽  
Houttuynia Cordata ◽  
Mesenchymal Transition ◽  
Prostate Carcinogenesis ◽  
Castration Resistant ◽  
Houttuynia Cordata Thunb

Houttuynia cordata Thunb. (HCT) is a well-known Asian medicinal plant with biological activities used in the treatment of many diseases including cancer. This study investigated the effects of HCT extract and its ethyl acetate fraction (EA) on prostate carcinogenesis and castration-resistant prostate cancer (CRPC). HCT and EA induced apoptosis in androgen-sensitive prostate cancer cells (LNCaP) and CRPC cells (PCai1) through activation of caspases, down-regulation of androgen receptor, and inactivation of AKT/ERK/MAPK signaling. Rutin was found to be a major component in HCT (44.00 ± 5.61 mg/g) and EA (81.34 ± 5.21 mg/g) in a previous study. Rutin had similar effects to HCT/EA on LNCaP cells and was considered to be one of the active compounds. Moreover, HCT/EA inhibited cell migration and epithelial-mesenchymal transition phenotypes via STAT3/Snail/Twist pathways in LNCaP cells. The consumption of 1% HCT-mixed diet significantly decreased the incidence of adenocarcinoma in the lateral prostate lobe of the Transgenic rat for adenocarcinoma of prostate model. Similarly, tumor growth of PCai1 xenografts was significantly suppressed by 1% HCT treatment. HCT also induced caspase-dependent apoptosis via AKT inactivation in both in vivo models. Together, the results of in vitro and in vivo studies indicate that HCT has inhibitory effects against prostate carcinogenesis and CRPC. This plant therefore should receive more attention as a source for the future development of non-toxic chemopreventive agents against various cancers.

scholarly journals Ibrexafungerp: A First-in-Class Oral Triterpenoid Glucan Synthase Inhibitor

2021 ◽  
Vol 7 (3) ◽  
pp. 163 ◽  
Author(s):  
Sabelle Jallow ◽  
Nelesh P. Govender
Keyword(s):  
Pathogenic Fungi ◽  
Candida Spp ◽  
Fungal Cell ◽  
Favourable Safety ◽  
Favourable Safety Profile ◽  
Synthase Inhibitor ◽  
Increased Activity ◽  
In Vitro Data

Ibrexafungerp (formerly SCY-078 or MK-3118) is a first-in-class triterpenoid antifungal or “fungerp” that inhibits biosynthesis of β-(1,3)-D-glucan in the fungal cell wall, a mechanism of action similar to that of echinocandins. Distinguishing characteristics of ibrexafungerp include oral bioavailability, a favourable safety profile, few drug–drug interactions, good tissue penetration, increased activity at low pH and activity against multi-drug resistant isolates including C. auris and C. glabrata. In vitro data has demonstrated broad and potent activity against Candida and Aspergillus species. Importantly, ibrexafungerp also has potent activity against azole-resistant isolates, including biofilm-forming Candida spp., and echinocandin-resistant isolates. It also has activity against the asci form of Pneumocystis spp., and other pathogenic fungi including some non-Candida yeasts and non-Aspergillus moulds. In vivo data have shown IBX to be effective for treatment of candidiasis and aspergillosis. Ibrexafungerp is effective for the treatment of acute vulvovaginal candidiasis in completed phase 3 clinical trials.

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