scholarly journals Echocardiographic Characteristics of Left Ventricular Diastolic Dysfunction among Impaired Glucose Tolerance Patients

2020 ◽  
Vol 6 (1) ◽  
pp. 38-42
Author(s):  
AKM Mohiuddin Bhuiyan ◽  
Zakia Sultana ◽  
Md Fazlul Kader Khan ◽  
Abu Foyez M Motiour Rahman ◽  
M Razib Ahsan ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Diastolic Dysfunction ◽  
Impaired Glucose Tolerance ◽  
Systolic Function ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Case Group ◽  
Ventricular Diastolic Dysfunction ◽  
Group A ◽  
Group B

Background: The measurement of left ventricular diastolic dysfunction is important among the impaired glucose tolerance patients. Objectives: The purpose of the present study was to see the echocardiographic characteristics of left ventricular diastolic dysfunction among impaired glucose tolerance patients. Methodology: This cross sectional study was carried out in the Department of Cardiology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2005 to June 2007 for a period of two (02) years. Patients with impaired glucose tolerance (IGT) patients attending Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh and fulfilled selection criteria were included in this study as group A. The apparently healthy persons without cardiovascular disease were taken as group B. All the study subjects underwent 2D and M-mode echocardiography for chamber enlargement, ventricular hypertrophy and ventricular systolic function according to recommendation of American Society of Echocardiography. Result: 2D and M-mode echocardiographic characteristics were compared between groups. Among the parameters, LA size in the group A was 31.18±3.49 mm and in group B was 25.22±4.95 mm which was significantly higher (p<0.01) in the case group. LA size was also compared among left ventricular diastolic dysfunction (LVDD) present and absent group, which was (32.76±4.61 vs 28.79±4.11 mm, p<0.001) significantly higher in the LVDD present group. Conclusion: In conclusion there is a significant differences of echocardiographic characteristics of left ventricular diastolic dysfunction among impaired glucose tolerance patients. Journal of National Institute of Neurosciences Bangladesh, 2020;6(1): 38-42

scholarly journals Pulmonary Venous Flow Pattern due to Left Ventricular Diastolic Dysfunction among Impaired Glucose Tolerance Patients

2020 ◽  
Vol 7 (1) ◽  
pp. 3-6
Author(s):  
AKM Mohiuddin Bhuiyan ◽  
KAM Mahbub Hasan ◽  
Partho Pratim Saha ◽  
HEM Rejwanur Rahman ◽  
Zakia Sultana ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Diastolic Dysfunction ◽  
Impaired Glucose Tolerance ◽  
Flow Pattern ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Venous Flow ◽  
Pulmonary Venous Flow ◽  
Ventricular Diastolic Dysfunction ◽  
Group A

Background: The pattern of pulmonary venous flow due to left ventricular diastolic dysfunction is important among impaired glucose tolerance patients. Objectives: The purpose of the present study was to observe the pulmonary venous flow pattern due to left ventricular diastolic dysfunction among impaired glucose tolerance patients. Methodology: This cross sectional study was carried out in the Department of Cardiology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2005 to June 2007. Impaired glucose tolerance (IGT) patients attending Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders, Dhaka, Bangladesh were included in this study as group A. The apparently healthy persons without cardiovascular disease were taken as group B. All the study subjects underwent 2D and M-mode echocardiography. Result: Doppler pulmonary inflow parameters of group A and group B showed no statistically' significant difference in peak S-wave (46.42+10.06 vs 51.20±8.34 cm/s, P>0.05), peak D-wave (34.86±8.01 vs 40.48±5.77 cm/s, P>0.05) and S/D, ratio (1.35±0.21 vs 1.20±0.13, P>0.05). Doppler pulmonary inflow parameters were compared between left ventricular diastolic dysfunction present and absent in group A which showed no statistically significant differences in peak S-wave (p>0.01), peak D-wave (p>0.50), S/D ratio (p>0.05). Conclusion: In conclusion the pulmonary venous flow pattern is significantly difference due to left ventricular diastolic dysfunction among impaired glucose tolerance patients. Journal of Current and Advance Medical Research 2020;7(1): 3-6

scholarly journals Grading of Left Ventricular Diastolic Dysfunction with Preserved Systolic Function by the 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging Recommendations Contributes to Predicting Cardiovascular Events in Hemodialysis Patients

2019 ◽  
Vol 9 (3) ◽  
pp. 190-200 ◽  
Author(s):  
Tatsunori Toida ◽  
Reiko Toida ◽  
Risa Yamashita ◽  
Norihiro Komiya ◽  
Shigehiro Uezono ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Cardiovascular Events ◽  
Systolic Function ◽  
Hemodialysis Patients ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Kaplan Meier ◽  
Ventricular Diastolic Dysfunction ◽  
Cox's Regression ◽  
American Society

Background: Left ventricular diastolic dysfunction (LVDD) causes heart failure with a preserved left ventricular ejection fraction (LVEF) in the general population. Objective: To examine the relationships between the LVDD grades of the 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging (ASE/EACVI) recommendations and several arteriosclerotic parameters and major cardiovascular events (MACE) in hemodialysis patients with preserved LVEF. Method: Sixty-three prevalent hemodialysis patients (median age [interquartile range], 69 [64–75] years, 31.7% female) with normal systolic function (LVEF > 50%) were enrolled. LVDD evaluated by echocardiography at baseline was divided into three groups according to ASE/EACVI recommendations (normal diastolic function [ND], n = 24; intermediate, n = 19; diastolic dysfunction [DD], n = 20). All patients underwent analyses of several arteriosclerotic parameters (carotid intima-media thickness [CIMT], plaque score [PS], ankle brachial index [ABI], and brachial-ankle pulse wave velocity [baPWV]). The presence or absence of postdialysis orthostatic hypotension was assessed in each dialysis session. MACE during the 1-year follow-up period was obtained from medical records. Kaplan-Meier and Cox’s regression analyses were used to investigate the relationship between LVDD grades and MACE. Results: Postdialysis orthostatic hypotension and PS, but not CIMT, ABI, or baPWV, increased proportionally with LVDD grades. Eleven patients developed MACE, including 2 cardiovascular deaths. The Kaplan-Meier analysis showed that MACE frequently occurred in the DD grade (p = 0.002 by the log-rank test). Cox’s regression analysis adjusted for potential confounders (age, sex, diabetes, systolic blood pressure, and body mass index) revealed that the DD grade was associated with MACE when the ND grade was set as a reference. Conclusions: In maintenance hemodialysis patients with normal ventricular systolic function, a classification of LVDD by the 2016 ASE/EACVI recommendations may be a useful tool for predicting cardiovascular events.

scholarly journals Left ventricle diastolic dysfunction in diabetes: an update

2007 ◽  
Vol 51 (2) ◽  
pp. 168-175 ◽  
Author(s):  
Cláudia Maria V. Freire ◽  
Ana Luiza M.T. Moura ◽  
Márcia de Melo Barbosa ◽  
Lucas José de C. Machado ◽  
Anelise Impeliziere Nogueira ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Systolic Function ◽  
Systolic Dysfunction ◽  
Tissue Doppler ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Diabetic Patients ◽  
Detailed Evaluation ◽  
Ventricular Diastolic Dysfunction ◽  
And Function

Diabetes mellitus, a disease that has been reaching epidemic proportions, is an important risk factor to the development of cardiovascular complication. Diabetes causes changes within the cardiac structure and function, even in the absence of atherosclerotic disease. The left ventricular diastolic dysfunction (VE) represents the earliest pre-clinical manifestation of diabetic cardiomyopathy, preceding the systolic dysfunction and being able to evolve to symptomatic heart failure. The doppler echocardiography has emerged as an important noninvasive diagnostic tool, providing reliable data in the stages of diastolic function, as well as for systolic function. With the advent of recent echocardiographic techniques, such as tissue Doppler and color M-mode, the accuracy in identifying the moderate diastolic dysfunction, the pseudonormal pattern, has significantly improved. Due to cardiometabolic repercussions of DM, a detailed evaluation of cardiovascular function in diabetic patients is important, and some alterations may be seen even in patients with gestational diabetes.

scholarly journals Prevalence of left ventricular diastolic dysfunction by cardiac magnetic resonance imaging in thalassemia major patients with normal left ventricular systolic function

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Benjaporn Chinprateep ◽  
Nithima Ratanasit ◽  
Yodying Kaolawanich ◽  
Khemajira Karaketklang ◽  
Pairash Saiviroonporn ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Systolic Function ◽  
Left Ventricular Systolic Function ◽  
Thalassemia Major ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Beta Thalassemia ◽  
Ventricular Systolic Function ◽  
Normal Left Ventricular ◽  
Ventricular Diastolic Dysfunction

Abstract Background The leading cause of mortality of thalassemia major patients is iron overload cardiomyopathy. Early diagnosis with searching for left ventricular diastolic dysfunction before the systolic dysfunction ensued might yield better prognosis. This study aimed to define the prevalence of the left ventricular diastolic dysfunction (LVDD) in thalassemia major patients with normal left ventricular systolic function and the associated factors. Methods Adult thalassemia major patients with normal left ventricular systolic function who were referred for cardiac T2* at Siriraj Hospital – Thailand’s largest national tertiary referral center – during the October 2014 to January 2017 study period. Left ventricular diastolic function was defined by mitral valve filling parameters and left atrial volume index using CMR. Patients with moderate to severe valvular heart disease, pericardial disease, or incomplete data were excluded. Baseline characteristics, comorbid diseases, current medication, and laboratory results were recorded and analyzed. Results One hundred and sixteen patients were included, with a mean age of 27.5 ± 13.5 years, 57.8% were female, and 87.9% were transfusion dependent. Proportions of homozygous beta-thalassemia and beta-thalassemia hemoglobin E were 12.1 and 87.9%, respectively. The baseline hematocrit was 26.3 ± 3.3%. The prevalence of LVDD was 20.7% (95% CI: 13.7–29.2%). Cardiac T2* was abnormal in 7.8% (95% CI: 3.6–14.2%). Multivariate analysis revealed age, body surface area, homozygous beta-thalassemia, splenectomy, heart rate, and diastolic blood pressure to be significantly associated with LVDD. Conclusions LVDD already exists from the early stages of the disease before the abnormal heart T2 * is detected. Homozygous beta-thalassemia and splenectomy were strong predictors of LVDD. These data may increase awareness of the disease, especially in the high risk groups.

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