scholarly journals Chondroid Syringoma Involving the Sub-brow Area

2021 ◽  
Vol 62 (7) ◽  
pp. 983-988
Author(s):  
Jungyul Park ◽  
Hee-Young Choi
Keyword(s):  
Hair Loss ◽  
Skin Incision ◽  
High Signal ◽  
Lateral Side ◽  
Incomplete Resection ◽  
Direct Closure ◽  
Chondroid Syringoma ◽  
Full Thickness Excision ◽  
Collagenous Stroma ◽  
Capsular Rupture

Purpose: Chondroid syringoma of the skin is a rare subcutaneous tumor and localization in the eyelid and orbital region that has rarely been described. We report a case of chondroid syringoma that involved the sub-brow region and was accompanied by hair loss. Case summary: A 57-year-old women presented with a mass on the lateral side of the left sub-brow region which was observed 25 years earlier. The mass, which recurred 2 months after surgery at another hospital through a skin incision was accompanied by an itching sensation. The mass was not tender or ulcerated but was reddish with superficial blood vessels and had a smooth surface with hair loss at the site of the mass. The mass showed high signal intensity on a T2-weighted magnetic resonance image and a round echogenic nodule with an irregular hypoechoic portion was observed on ultrasonography. A full-thickness excision including the adjacent normal tissue of the sub-brow mass and direct closure were subsequently performed. The pathological diagnosis was chondroid syringoma which was revealed as numerous tubular structures with various lumens in a collagenous stroma. Mucinous and fibrous findings were also observed. No recurrence was detected during the first 2 years after surgery. Conclusions: Chondroid syringoma in the eyelid and sub-brow region is uncommon. Complete resection is required to differentiate it from a malignancy and reduce the possibility of recurrence. Incomplete resection or capsular rupture during removal of the tumor could induce recurrence or a malignant change in the tumor.

scholarly journals Usefulness of Autofluorescence Video-Monitoring to Enhanced Localization of Parathyroid Glands

2020 ◽  
Vol 63 (12) ◽  
pp. 586-593
Author(s):  
Sung Won Kim ◽  
Yoon Soo Seo ◽  
Hyoung Shin Lee ◽  
Yikeun Kim ◽  
Yeh-Chan Ahn ◽  
...  
Keyword(s):  
Real Time ◽  
Parathyroid Gland ◽  
Parathyroid Glands ◽  
Video Monitoring ◽  
High Signal ◽  
Lateral Side ◽  
Fluorescence Signal ◽  
Video Monitor ◽  
Room Light ◽  
Monitoring Technique

Background and Objectives Near-infrared (NIR) fluorescence photo imaging provides real time parathyroid anatomy enhancement. Moreover, autofluorescence enables intraoperative virtual reality parathyroid exploration of the optical characteristics of the parathyroid gland. This study was performed to demonstrate the new technique of visualizing the parathyroid gland using video-guided autofluorescence during thyroid and parathyroid surgery and to evaluate the outcomes. This is the first study that introduces the video-monitoring technique for intraoperative parathyroid mapping.Subjects and Method A total of 26 patients underwent 18 total thyroidectomies and 8 hemithyroidectomies in 2016. Fifty-six parathyroid glands were enrolled in this study. Surgery was performed by NIR video-monitoring via thyroid lateral side dissection to find the parathyroid tissues and extract the thyroid glands. With the operation room light turned on, the parathyroid glands were identified by the video-guided autofluorescence detection technique carried out in 3 stages (P1, P2, and P3), which are imaging with surgeon’s eyes before parathyroids exposure (P1), after identification (P2), and in extracted specimen (P3).Results The parathryoid autofluorescence could be video-monitored in real time by our NIR camera system with the indoor room light turned on. Of the total 56 parathyroids, 52 were detected by fluorescence. Of these, the location of 43 glands were predicted by using the high signal in a before-exposure state and the glands were confirmed as containing parathyroid tissues [in P1, sensitivity=82.69%, positive predictive value (PPV)=100.00%]. Of the nine glands that did not show high signals in P1, seven glands visually showed fluorescence signals (in P1 and P2, sensitivity=96.15%, PPV=100.00%). One of the two glands that showed high signals in the extracted tissue was identified as parathyroid, but the other one was proved not by histologic examination by despite high intensity fluorescence signal (in P1-P3, sensitivity=100.00%, PPV=98.08%). The accuracy of video-guided parathyroid mapping in P1, P2, and P3 were 83.93%, 96.43%, and 96.43%, respectively.Conclusion This is the first study that demonstrates the parathyroid gland autofluorescence as a real-time video-monitoring technique and shows that it could be applied to real surgery. Although parathyroid autofluorescence is a phenomenon seen in the invisible wavelength, our data suggest that the operator can see the parathyroid fluorescent signal in real time on the video-monitor. This technique could help the operator to predict the gland location and preserve them safely.

scholarly journals Rapidly Growing Chondroid Syringoma of the External Auditory Canal: Report of a Rare Case

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Ioannis Vasileiadis ◽  
Stylianos Kapetanakis ◽  
Aristotelis Petousis ◽  
Euthimios Karakostas ◽  
Christos Simantirakis
Keyword(s):  
External Auditory Canal ◽  
Bone Erosion ◽  
Normal Skin ◽  
Benign Neoplasm ◽  
External Auditory Meatus ◽  
Posterior Wall ◽  
Benign Tumors ◽  
High Signal ◽  
Chondroid Syringoma ◽  
Intensity Lesion

Introduction. Chondroid syrinoma of the external auditory canal is an extremely rare benign neoplasm representing the cutaneous counterpart of pleomorphic adenoma of salivary glands. Less than 35 cases have been reported in the international literature.Case Presentation. We report a case of a 34-year-old male in whom a rapidly growing, well-circumscribed tumor arising from the external auditory canal was presented. Otoscopy revealed a smooth, nontender lesion covered by normal skin that almost obstructs the external auditory meatus. MRI was performed to define the extension of the lesion. It confirmed the presence of a1.5×0.8 cm T2 high-signal intensity lesion in the superior and posterior wall of EAC without signs of bone erosion. The patient underwent complete resection of the tumor. The diagnosis was confirmed by histopathologic examination.Conclusion. Although chondroid syringoma is extremely rare, it should always be considered in the differential diagnosis of an aural polyp. Chondroid syringomas are usually asymptomatic, slow-growing, single benign tumors in subcutaneous or intradermal location. In our case, the new information is that this benign tumor could present also as a rapidly growing lesion, arising the suspicion for malignancy.

Acquisition of EELS spectra for high-resolution spectroscopy

1993 ◽  
Vol 51 ◽  
pp. 578-579
Author(s):  
Maoxu Qian ◽  
Mehmet Sarikaya ◽  
Edward A. Stern
Keyword(s):  
Energy Loss ◽  
Detection System ◽  
High Resolution Spectroscopy ◽  
High Signal ◽  
Short Report ◽  
Edge Structure ◽  
High Background ◽  
Gain Variation ◽  
Sufficient Energy ◽  
On Line

It is difficult, in general, to perform quantitative EELS to determine, for example, relative or absolute compositions of elements with relatively high atomic numbers (using, e.g., K edge energies from 500 eV to 2000 eV), to study ELNES (energy loss near edge structure) signal using the white lines to determine oxidation states, and to analyze EXELFS (extended energy loss fine structure) to study short range ordering. In all these cases, it is essential to have high signal-to-noise (S/N) ratio (low systematical error) with high overall counts, and sufficient energy resolution (∽ 1 eV), requirements which are, in general, difficult to attain. The reason is mainly due to three important inherent limitations in spectrum acquisition with EELS in the TEM. These are (i) large intrinsic background in EELS spectra, (ii) channel-to-channel gain variation (CCGV) in the parallel detection system, and (iii) difficulties in obtaining statistically high total counts (∽106) per channel (CH). Except the high background in the EELS spectrum, the last two limitations may be circumvented, and the S/N ratio may be attained by the improvement in the on-line acquisition procedures. This short report addresses such procedures.

Chondroid syringoma

1972 ◽  
Vol 106 (3) ◽  
pp. 419c-420 ◽  
Author(s):  
E. G. Thorne
Keyword(s):  
Chondroid Syringoma

Manage Expectations in Treating Pattern Hair Loss

2006 ◽  
Vol 37 (3) ◽  
pp. 41
Author(s):  
DAMIAN MCNAMARA
Keyword(s):  
Hair Loss

High-Dose Finasteride Halts Hair Loss in Women

2012 ◽  
Vol 43 (12) ◽  
pp. 5
Author(s):  
BRUCE JANCIN
Keyword(s):  
Hair Loss ◽  
High Dose

Minimally Invasive Repair of Pectus Excavatum (MIRPE) - The Basel Experience

Swiss Surgery ◽  
2003 ◽  
Vol 9 (6) ◽  
pp. 289-295 ◽  
Author(s):  
Haecker ◽  
Bielek ◽  
von Schweinitz
Keyword(s):  
Minimally Invasive ◽  
Pectus Excavatum ◽  
Pulmonary Function Tests ◽  
Preoperative Evaluation ◽  
Skin Incision ◽  
Original Method ◽  
Restrictive Lung Disease ◽  
Cardiac Compression ◽  
Cardiac Evaluation ◽  
Indications For Operation

Purpose: Minimally invasive repair of pectus excavatum (MIRPE) was first reported in 1998 by D. Nuss. This technique has gained wide acceptance during the last 4-5 years. In the meantime, some modifications of the technique have been introduced by different authors. Our retrospective study reports our own experience over the last 36 months and modifications introduced due to a number of complications. Methods: From 3/2000 to 3/2003, 22 patients underwent MIRPE. Patients median age was 15.5 years (10.7 to 20.3 years). Standardised preoperative evaluation included 3D computerised tomography (CT) scan, pulmonary function tests, cardiac evaluation with electrocardiogram and echocardiography, and photo documentation. Indications for operation included at least two of the following: Haller CT index > 3.2, restrictive lung disease, cardiac compression, progression of the deformity and severe psychological alterations. Results: In 22 patients (2 girls, 20 boys) undergoing MIRPE procedure, a single bar was used in 21 patients and two bars in one boy. Lateral stabilisers were fixed with non resorbable sutures on both sides. Overall, postoperative complications occurred in six patients (27.3%). In two patients (9.1%) a redo-procedure was necessary due to bar displacement. An additional median skin incision was performed in two patients to elevate the sternum. Pneumothorax or hematothorax in two patients resulted in routine use of a chest tube on both sides. Long-term favourable results were noted in all patients. Conclusions: The MIRPE procedure is an effective method with elegant cosmetic results. Modifications of the original method help to decrease the complication rate and to accelerate acquirement of expertise.

Thrombin Generation Measured Ex Vivo Following Microvasculor Injury Is Increased in SLE Patients with Antiphospholipid-protein Antibodies

1997 ◽  
Vol 78 (04) ◽  
pp. 1173-1177 ◽  
Author(s):  
Jacek Musiał ◽  
Jakub Swadźba ◽  
Miłosz Jankowski ◽  
Marek Grzywacz ◽  
Stanisława Bazan-Socha ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Thrombin Generation ◽  
Ex Vivo ◽  
Skin Incision ◽  
Anticardiolipin Antibodies ◽  
Small Blood Vessel ◽  
Anionic Phospholipids ◽  
Increased Risk ◽  
High Concentrations

SummaryAntiphospholipid-protein antibodies (APA) include lupus-type anticoagulant (LA) and antibodies recognizing complexes of anionic phospholipids (e.g. cardiolipin) and proteins (e.g. prothrombin and (β2-glycoprotein I). The presence of APA is associated with an increased risk of both arterial and venous thrombosis. However, the pathogenic mechanism leading to thrombosis in patients with APA remains unclear. We studied 32 patients with systemic lupus erythematosus (SLE) who were divided into two groups depending on the presence (n = 19) or absence (n = 13) of APA. Healthy volunteers (n = 12) matched by age and sex served as controls. In all subjects LA and IgG class anticardiolipin antibodies (ACA) were determined. Thrombin generation was monitored ex vivo measuring fibrinopeptide A (FPA) and prothrombin fragment F1 + 2 (F1 + 2) in blood emerging from a skin microvasculature injury, collected at 30 second intervals. In subjects with antiphospholipid antibodies mean FPA and F1 + 2 concentrations were signiF1cantly higher at most blood sampling times than in controls. In some SLE patients with APA the process of thrombin generation was clearly disturbed and very high concentrations of F1brinopeptide A were detected already in the F1rst samples collected. Two minutes after skin incision SLE patients without APA produced slightly more FPA, but not F1 + 2, as compared to healthy subjects. Mathematical model applied to analyze the thrombin generation kinetics revealed that APA patients generated signiF1cantly greater amounts of thrombin than healthy controls (p = 0.02 for either marker). In contrast, in the same patients generation of thrombin in recalciF1ed plasma in vitro was delayed pointing to the role of endothelium in the phenomenon studied. In summary, these data show for the F1rst time that in SLE patients with antiphospholipid-protein antibodies thrombin generation after small blood vessel injury is markedly increased. Enhanced thrombin generation might explain thrombotic tendency observed in these patients.

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