scholarly journals Clinical and instrumental indices and features of risk factors for patients with recurrent ischemic stroke

Author(s):  
O. Mykytei

The aim of the study was to improve the diagnostic approach in patients with re-ischemic stroke based on the analysis of risk factors for the dynamics of neurological deficiency, taking into account clinical and instrumental indices. We were examined 124 patients, of which 94 patients with ischemic stroke in acute period, which arrived in the hospital for up to 2 days after the onset of the disease and were observed in the neurological department. The control group consisted of 30 patients with hypertensive encephalopathy. The analysis of the indicators of daily blood pressure monitoring, duplex scan of vessels of the head and neck in patients with repetitive ischemic stroke indicates a progressive course of stroke, changes in the elastic properties of the vascular wall of the major arter- ies, and a decrease in their speed indicators, which leads to progression of the decrease in the volume of cerebral blood flow Brain of patients. The conducted research allowed to improve the efficiency of diagnostics of the development of repeat ischemic stroke by studying the features of central and cerebral hemodynamics.

Author(s):  
N. Svyrydova ◽  
O. Mykytei

To conduct a comparative analysis of daily blood pressure profile in patients with recurrent and primary ischemic stroke. We were examined 124 patients, of which 94 patients with ischemic stroke in acute period, which came to the hospital in up to 2 days after the onset of the disease and were observed in the neurological department. The control group consisted of 30 patients with hypertensive encephalopathy. The conducted analysis of daily blood pressure monitoring in patients with recurrent and primary ischemic stroke indicates the importance of using this diagnostic method as a reliable difference in many indicators of arterial pressure is obtained. The difference averages of daily monitoring of blood pressure for all periods day informative confirms the difference in blood pressure in patients with primary and repeated ischemic stroke, as observed significant difference of values: the day indices of systolic, diastolic, blood pressure pulse heart rate parameters. The study allowed to increase the effectiveness of the diagnosis of recurrent ischemic stroke by studying the characteristics of central hemodynamics.


2016 ◽  
Vol 88 (9) ◽  
pp. 119-124 ◽  
Author(s):  
V A Korneva ◽  
T Yu Kuznetsova

Arterial wall stiffness is an early marker of cardiovascular diseases. The gold standard for assessment of the stiffness of large vessels is presently pulse wave velocity (PWV). Work is in progress on the study of the reference values of PWV in people of different genders and ages. 24-hour blood pressure (BP) monitoring is not only a procedure that can estimate diurnal BP variability, but also monitor the indicators of vascular wall stiffness in a number of cases over a 24-hour period. The given review highlights the pathophysiology of arterial stiffness, methods for its assessment, and the aspects of use in therapeutic practice.


2021 ◽  
Vol 06 (02) ◽  
pp. 079-085
Author(s):  
Ghizal Fatima ◽  
Ashish Jha ◽  
Mohsin Ali Khan

Abstract Background Shift work is associated with behavioral, psychosocial, and physiological consequences in the body that may cause cardiovascular disease (CVD) risk. Therefore, in this study we tried to demonstrate the disruption in circadian rhythm of blood pressure by ambulatory blood pressure monitor in shift working nurses. Methods A total of 50 nurses, 25 night shift working nurses (NSWN), and 25 day shift working nurses (DSWN) underwent ambulatory blood pressure monitoring (ABPM) for a period of 24 hours. Along with measurements of inflammatory markers (hs-CRP and IL-6) the risk factors for cardiovascular disease between NSWN and DSWN and their possible relationship with disrupted circadian rhythm were measured by circadian rhythm questionnaire. Results The mean systolic and diastolic pressure for a period of 24 hours and mean diastolic blood pressure analysis throughout the sleep time was found greater in the NSWN than the DSWN (118 mm Hg vs. 112 mm Hg, p < 0.05: 72 mm Hg vs. 68 mm Hg, p < 0.05: 62 mm Hg vs. 59 mm Hg, p < 0.05). High mean blood pressure readings were found to be more frequent in the NSWN (p < 0.05) than in DSWN. No significant differences were found in IL-6 and hs-CRP levels. However, a significant difference in circadian rhythm abnormality was found in NSWN than in DSWN. Conclusion The 7 day/24 hours ambulatory blood pressure monitoring (ABPM) in NSWN showed a reduced circadian rhythm variation in blood pressure along with abnormality in circadian rhythm itself as compared with DSWN. Work schedules and the consequent rest–activity schedules affect circadian rhythms, with likely long-term impact on health. Therefore, working in critical care unit during night hours leads to abnormal blood pressure in NSWN, suggesting that this type of work, in which sleep is disturbed, leading to mental stress, could be a direct risk factor in cardiovascular diseases.


2020 ◽  
Vol 11 ◽  
pp. 204062232093310
Author(s):  
Hailan Zhu ◽  
Xiaoyan Liang ◽  
Xiong-Fei Pan ◽  
Chunyi Huang ◽  
Jian Kuang ◽  
...  

Background: Hypertension, as a predominant risk factor for cardiovascular disease, is a severe public health burden in China. Home blood pressure monitoring (HBPM) is an important tool in the detection and management of hypertension. However, there is a lack of HBPM data from prospective cohorts in China. Hence, we designed this study to investigate the impact of HBPM on major health outcomes in Chinese population participating in regular health check-ups. Methods: Leveraging telemedicine technology, the open prospective, multicenter, HBPM-iCloud (Home Blood Pressure Monitoring Based on an Intelligent Cloud Platform) cohort study will recruit participants from three participating health check-up centers in southern China to participate in cloud-based HBPM for 1 week. The prevalence of sustained hypertension, white coat hypertension (WCH), masked hypertension (MH), white coat uncontrolled hypertension (WUCH), and masked uncontrolled hypertension (MUCH) will be defined by a combination of average readings of home-based and office-based blood pressure (BP). Cardiovascular risk factors and subclinical target organ damage will be recorded. Participants will be followed-up for 5 years to examine the incidence and associated risk factors of composite major adverse cardiovascular and cerebrovascular event. Conclusion: The study will help to determine the best way to implement telemedicine technology in BP control for better prevention and treatment of hypertension. Results will provide data for a Chinese population to aid in the construction of screening, risk stratification, and intervention strategies for abnormal BP phenotypes, including WCH, MH, WUCH, and MUCH.


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