scholarly journals Acoustic analysis of swallowing as an auxiliary method for assessing dysphagia in Parkinson's disease

2021 ◽  
Vol 10 (16) ◽  
pp. e323101623298
Author(s):  
Glauce Souza da Silva ◽  
Ana Clara Gonçalves de Figueiredo ◽  
Bianca Simone Zeigelboim ◽  
Cristiano Miranda de Araújo ◽  
José Stechmann Neto ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Predictive Value ◽  
Acoustic Analysis ◽  
Screening Method ◽  
Oropharyngeal Dysphagia ◽  
Accuracy Study ◽  
Swallow Study ◽  
Videofluoroscopic Swallow Study ◽  
Tracheal Aspiration

Objective: To measure the accuracy of DeglutiSom as an auxiliary method to assess swallowing in patients with Parkinson's disease (PD). Methodology: Accuracy study. Among 248 individuals, 91 participants met the inclusion criteria, with a mean age of 64.9 years (SD 7.7), 53.8% male and 46.2% female, with a mean disease duration of 12.6 years (SD 3.8 years). Two instrumental studies were performed: An acoustic analysis with Sonar Doppler via the DeglutiSom Software, and a videofluoroscopic swallow study. Three judges analyzed the swallowing sounds in the DeglutiSom software and the instrumental examination findings. Results: The inter-rater reliability was 90.1%, with 4.4% degree of partial agreement and 5.5% disagreement. Sensitivity resulted in 90.0% and specificity in 90.0%. A sensitivity of 97.0% and specificity of 91.0% are indicators of a high validity for the dysphagia screening method, with predictive value (+) of 97.0% and predictive value (-) of 91.0%, with an accuracy method of 96.0%. The validity indicator values for screening aspiration were also high, with a sensitivity of 90.0%, specificity of 90.0%, predictive value (+) of 82.0%, predictive value (-) of 95% , 0% and 90.0% accuracy. Conclusion: The method proposed is considered appropriate for oropharyngeal dysphagia and tracheal aspiration screening in patients with Parkinson's Disease.

Videofluoroscopic Swallow Studies and Diagnostic Outcomes in Otherwise Healthy Infants With Dysphagia

2021 ◽  
pp. 000348942110477
Author(s):  
Michael C. Shih ◽  
Christina Rappazzo ◽  
Caroline Hudson ◽  
Julina Ongkasuwan
Keyword(s):  
Chart Review ◽  
Future Research ◽  
Silent Aspiration ◽  
Healthy Infants ◽  
Laryngeal Penetration ◽  
Swallow Study ◽  
Videofluoroscopic Swallow Study ◽  
Diagnostic Outcomes ◽  
Tracheal Aspiration

Objectives: To evaluate videofluoroscopic swallow study (VFSS) findings in infants with dysphagia and without prior diagnoses, and to characterize the outcomes and any diagnoses that follow. Methods: A chart review of all pediatric patients who received a VFSS at a tertiary children’s hospital from November 2008 to March 2017 was performed. Results: There were 106 infants (57 males and 49 females) with 108 VFSS. VFSS was normal in 18 (16.98%) infants. Regarding airway protection, 50 (47.17%) infants had laryngeal penetration, and 8 (7.55%) had tracheal aspiration; 3 (2.83%, 37.5% of all aspirators) exhibited silent aspiration. Of the 75 infants with minimum 2-year follow-up, 35 (46.67%) had no sequelae of disease and received no diagnoses. The most common diagnoses and pathologic sequelae were gastroesophageal reflux (n = 18, 24.00%), asthma (n = 8, 10.67%), laryngomalacia (n = 6, 8.00%), and tracheomalacia (n = 4, 5.33%), all consistent with United States pediatric data on prevalence. All infants (n = 51) with follow-up for dysphagia had resolution of symptoms within 9 months from VFSS order date. Conclusions: Otherwise healthy infants may show signs of dysphagia and not develop later illness. Parents can thus be counseled on the implications of dysphagia in a previously healthy infant. Our findings provide comparative statistics for future research in pediatric dysphagia.

scholarly journals Impact of levodopa treatment in the voice pattern of Parkinson’s disease patients: a systematic review and meta-analysis

CoDAS ◽  
2018 ◽  
Vol 30 (5) ◽  
Author(s):  
Patrícia Pinho ◽  
Larissa Monteiro ◽  
Maria Francisca de Paula Soares ◽  
Lorena Tourinho ◽  
Ailton Melo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Acoustic Analysis ◽  
Meta Analysis ◽  
Speech Disorders ◽  
Levodopa Therapy ◽  
Eligibility Criteria ◽  
Perceptual Analysis ◽  
Vocal Intensity

Abstract Purpose Investigate the association between levodopa therapy and vocal characteristics in Parkinson’s disease patients. Search strategy Studies published at MEDLINE, LILACS, and SciELO, from 1960 to December 2016. A systematic review and meta-analysis was performed using the following keywords: Parkinson’s disease; levodopa; L-dopa; voice; speech disorders; dysphonia; dysarthria. After analyzing titles and abstracts, two independent reviewers selected all clinical trials that met the eligibility criteria and selected the articles and the data recorded in a previously standardized table. Selection criteria Trials published in English between 1960 and December 2016 individuals with clinical diagnosis of Parkinson’s disease; use of levodopa therapy in stable doses; acoustic analysis combined or not with auditory-perceptual analysis to evaluate the vocal parameters under investigation. Data analysis The following vocal parameters were analyzed: fundamental frequency (F 0), jitter, and vocal intensity. Standardized mean differences (SMD) were calculated using the Comprehensive Meta-analysis V2 software. Results Nine articles met the eligibility criteria and were selected, with a total of 119 individuals. From these, six articles with 83 individuals were included in the meta-analysis. During the levodopa therapy “on” state, modifications in F 0 (SMD=0.39; 95% CI - 0.21-0.57) and jitter (SMD=0.23; 95% CI - 0.02-0.45) were observed. Vocal intensity was not affected (SMD=0.09; 95% CI - 0.22-0.39) by levodopa ingestion. Data of the included studies were controversial in the auditory-perceptual analysis of voice. Conclusion Levodopa therapy modifies F0 and jitter. No changes in vocal intensity were observed in either the “on” or “off” states of levodopa therapy.

scholarly journals Changes in Phonation and Their Relations with Progress of Parkinson’s Disease

2018 ◽  
Vol 8 (12) ◽  
pp. 2339 ◽  
Author(s):  
Zoltan Galaz ◽  
Jiri Mekyska ◽  
Vojtech Zvoncak ◽  
Jan Mucha ◽  
Tomas Kiska ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Scientific Community ◽  
Partial Correlation ◽  
Acoustic Analysis ◽  
Partial Correlation Analysis ◽  
Clinical Scales ◽  
Clinical Scores ◽  
The Relationship

Hypokinetic dysarthria, which is associated with Parkinson’s disease (PD), affects several speech dimensions, including phonation. Although the scientific community has dealt with a quantitative analysis of phonation in PD patients, a complex research revealing probable relations between phonatory features and progress of PD is missing. Therefore, the aim of this study is to explore these relations and model them mathematically to be able to estimate progress of PD during a two-year follow-up. We enrolled 51 PD patients who were assessed by three commonly used clinical scales. In addition, we quantified eight possible phonatory disorders in five vowels. To identify the relationship between baseline phonatory features and changes in clinical scores, we performed a partial correlation analysis. Finally, we trained XGBoost models to predict the changes in clinical scores during a two-year follow-up. For two years, the patients’ voices became more aperiodic with increased microperturbations of frequency and amplitude. Next, the XGBoost models were able to predict changes in clinical scores with an error in range 11–26%. Although we identified some significant correlations between changes in phonatory features and clinical scores, they are less interpretable. This study suggests that it is possible to predict the progress of PD based on the acoustic analysis of phonation. Moreover, it recommends utilizing the sustained vowel /i/ instead of /a/.

scholarly journals Acoustic and hearing-perceptual voice analysis in individuals with idiopathic Parkinson's disease in "on" and "off" stages

2010 ◽  
Vol 68 (5) ◽  
pp. 706-711 ◽  
Author(s):  
Luiza Lara M Santos ◽  
Larissa Oliveira dos Reis ◽  
Iara Bassi ◽  
Clara Guzella ◽  
Francisco Cardoso ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Acoustic Analysis ◽  
Voice Quality ◽  
Control Group ◽  
Idiopathic Parkinson’S Disease ◽  
Acoustic Parameters ◽  
Perceptual Analysis ◽  
Idiopathic Parkinson's Disease ◽  
Vocal Quality

OBJECTIVE: To evaluate the voice quality of patients with idiopathic Parkinson's disease, at the "on" and "off" moments of the disease. METHOD: Five individuals with Parkinson's disease and five of the control group were assessed. All of them underwent the recording of voice and speech. The acoustic parameters analyzed were: fundamental frequency, jitter, shimmer, harmonic noise proportion and index of tremor, besides performing the hearing-perceptual analysis by means of GRBASI scale. The findings were analyzed using statistics through t test and the level of significance adopted was p<0.05. RESULTS: There was no difference in the acoustic parameters in the three analyzed groups. In the hearing-perceptual analysis, patients with idiopathic Parkinson's disease showed altered voice quality and the ones from the control group, neutral vocal quality. CONCLUSION: Patients with idiopathic Parkinson's disease present rough, breathy and unstable vocal quality in both stages. In the acoustic analysis, there are no differences in the studied parameters.

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