scholarly journals Gene Expression Analysis of Cultured Amniotic Fluid Cell with Down Syndrome by DNA Microarray

2005 ◽  
Vol 20 (1) ◽  
pp. 82 ◽  
Author(s):  
In-Hyuk Chung ◽  
Sook-Hwan Lee ◽  
Kyo-Won Lee ◽  
Sang-hee Park ◽  
Kwang-Yul Cha ◽  
...  
2013 ◽  
Vol 33 (9) ◽  
pp. 873-883 ◽  
Author(s):  
Lisa Hui ◽  
Heather C. Wick ◽  
Kenneth J. Moise ◽  
Anthony Johnson ◽  
Francois Luks ◽  
...  

2013 ◽  
Vol 121 (6) ◽  
pp. 1248-1254 ◽  
Author(s):  
Lisa Hui ◽  
Heather C. Wick ◽  
Andrea G. Edlow ◽  
Janet M. Cowan ◽  
Diana W. Bianchi

2008 ◽  
Vol 19 (2) ◽  
pp. 173-181 ◽  
Author(s):  
Norinaga Kojima ◽  
Shogo Ozawa ◽  
Yasuhiro Miyata ◽  
Hideki Hasegawa ◽  
Yoshinobu Tanaka ◽  
...  

Blood ◽  
2009 ◽  
Vol 113 (17) ◽  
pp. 3953-3960 ◽  
Author(s):  
Andrea Ditadi ◽  
Paolo de Coppi ◽  
Olivier Picone ◽  
Laetitia Gautreau ◽  
Rim Smati ◽  
...  

Abstract We have isolated c-Kit+Lin− cells from both human and murine amniotic fluid (AF) and investigated their hematopoietic potential. In vitro, the c-Kit+Lin− population in both species displayed a multilineage hematopoietic potential, as demonstrated by the generation of erythroid, myeloid, and lymphoid cells. In vivo, cells belonging to all 3 hematopoietic lineages were found after primary and secondary transplantation of murine c-Kit+Lin− cells into immunocompromised hosts, thus demonstrating the ability of these cells to self-renew. Gene expression analysis of c-Kit+ cells isolated from murine AF confirmed these results. The presence of cells with similar characteristics in the surrounding amnion indicates the possible origin of AF c-Kit+Lin− cells. This is the first report showing that cells isolated from the AF do have hematopoietic potential; our results support the idea that AF may be a new source of stem cells for therapeutic applications.


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