Signal Intensity Changes of Normal Brain at Varying High b-Value Diffusion-Weighted Images Using 3.0T MR Scanner

2003 ◽  
Vol 49 (6) ◽  
pp. 455 ◽  
Author(s):  
Jin Hee Lee ◽  
Chul Ho Sohn ◽  
Jin Soo Choi
2013 ◽  
Vol 24 (1) ◽  
pp. 209-213 ◽  
Author(s):  
Michael Quentin ◽  
Lars Schimmöller ◽  
Christian Arsov ◽  
Robert Rabenalt ◽  
Gerald Antoch ◽  
...  

Author(s):  
A Rezaeian ◽  
M J Tahmasebi Birgani ◽  
N Chegeni ◽  
M Sarkarian ◽  
M Gh Hanafi ◽  
...  

Background: Diffusion-weighted imaging (DWI) is a main component of multiparametric MRI for prostate cancer detection. Recently, high b value DWI has gained more attention because of its capability for tumor characterization.Objectives: To assess based on histopathological findings of transrectal ultrasound (TRUS)-guided prostate biopsy as a reference, an increase in signal intensity of prostatic lesions in comparison with normal background tissue on high b-value diffusion-weighted images could be a sign of malignancy. Material and Methods: Fifty-three consecutive patients retrospectively included in the study. All patients underwent routine TRUS-guided prostate biopsies involving 12 cores after the magnetic resonance imaging (MRI) examinations. In seventeen patients (n =35 lesions), the prostate cancer was histologically confirmed by TRUS-guided prostate biopsy. The biopsy results of other patients were negative. Signal intensities on the high b-value (1600 s/mm2) images of the peripheral zone, the central gland, and the defined lesions were evaluated using region of interest-based measurements. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for prostate cancer detection using signal intensity of high b value diffusion-weighted images were calculated.Results: In the patients with confirmed prostate cancer, fourteen had visually increased SI on the high b-value images. The SI of lesions for these patients was higher than the SI of peripheral zone (22±18%) or central gland (31±20%). In patients with a negative biopsy, eight had visually increased SI on the high b-value images. The SI of lesions for these patients was 23±21% and 35±18% higher than the SI in the peripheral zone and the central gland, respectively. The sensitivity, specificity, PPV, and NPV for prostate cancer using SI of high b value DWI were 71, 87, 62, and 87 %, respectively.Conclusions: Visually increased SI on the high b-value images can be an indication of malignancy, although some benign lesions also show this increase in signal intensity. 


2019 ◽  
Vol 43 (3) ◽  
pp. 434-442
Author(s):  
Fangrong Zong ◽  
Sebastian Bickelhaupt ◽  
Tristan Anselm Kuder ◽  
Wolfgang Lederer ◽  
Heidi Daniel ◽  
...  

2009 ◽  
Vol 30 (1) ◽  
pp. 243-248 ◽  
Author(s):  
Sharon Peled ◽  
Stephen Whalen ◽  
Ferenc A. Jolesz ◽  
Alexandra J. Golby

Author(s):  
Christine U. Lee ◽  
James F. Glockner

56-year-old man with progressive solid-food dysphagia and a 15-lb weight loss over the past 3 months Axial fat-suppressed FSE T2-weighted images (Figure 9.2.1) show circumferential thickening and mildly increased signal intensity in the distal esophagus. Axial diffusion-weighted images with a b value of 600 s/mm...


2011 ◽  
Vol 34 (1) ◽  
pp. 95-100 ◽  
Author(s):  
Andrew B. Rosenkrantz ◽  
Lorenzo Mannelli ◽  
Xiangtian Kong ◽  
Ben E. Niver ◽  
Douglas S. Berkman ◽  
...  

2001 ◽  
Vol 25 (4) ◽  
pp. 515-519 ◽  
Author(s):  
Jonathan H. Burdette ◽  
David D. Durden ◽  
Allen D. Elster ◽  
Yi-Fen Yen

2011 ◽  
Vol 67 (6) ◽  
pp. 1694-1702 ◽  
Author(s):  
Shani Ben-Amitay ◽  
Derek K. Jones ◽  
Yaniv Assaf

2009 ◽  
Vol 69 (3) ◽  
pp. 454-458 ◽  
Author(s):  
Mutlu Cihangiroglu ◽  
Aziz Müfit Uluğ ◽  
Zeynep Firat ◽  
Ali Bayram ◽  
Arzu Kovanlikaya ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document