The Long-Term Effect of an Independent Capacity Protocol on Emergency Department Length of Stay: A before and after Study

Summary In 30 atherosclerotic patients different serum analytes and neopterin concentrations in serum and urine were determined before and after Heparin-Induced Extracorporeal LDL and Fibrinogen Precipitation therapy. Neopterin concentrations in serum of all 30 patients were increased (mean=9.18 nmol/l, SD=3.23) compared to age matched healthy people (mean=5.34 nmol/l, SD=2.70) and were significantly lowered after H.E.L.P therapy (mean=S.22 nmol/l; SD=3.22, p=0.002, t-test) . These results suggest the involvement of the cellular immune system in the occurrence of atherosclerosis. Further neopterin, the macrophagederived immune activation marker, is significantly correlated with fibrinogen (linear correlation coefficient r=0.36, p=0.05). Long-term neopterin concentrations in serum of 4 patients (three with coronary heart disease and one with Papilla edema), from the first up to the 9th, respectively 12th therapy decreased, in contrast to fibrinogen which stayed stable or even increased during long-term treatment.

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Does an Educational Session With an Infectious Diseases Physician Reduce the Use of Inappropriate Antibiotic Therapy for Inpatients With Positive Urine Culture Results? A Controlled Before-and-After Study

Infection Control and Hospital Epidemiology ◽

10.1086/597514 ◽

2009 ◽

Vol 30 (6) ◽

pp. 596-599 ◽

Cited By ~ 31

Author(s):

Patricia Pavese ◽

Nathalie Saurel ◽

José Labarère ◽

Corinne Decouchon ◽

Jean-Philippe Vittoz ◽

...

Keyword(s):

Infectious Diseases ◽

Antibiotic Therapy ◽

Urine Culture ◽

Positive Urine Culture ◽

Educational Session ◽

Long Term Effect ◽

Positive Urine ◽

Before And After ◽

Before And After Study

In this controlled before-and-after study involving 19 departments in a university-affiliated hospital, a single 1-hour educational session delivered by an infectious diseases physician reduced the use of inappropriate antibiotic therapy for inpatients with positive urine culture Results. Further study is warranted to assess the long-term effect of this intervention.

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The long-term effect of lockouts on alcohol-related emergency department attendances within Ballarat, Australia

Drug and Alcohol Review ◽

10.1111/j.1465-3362.2011.00375.x ◽

2011 ◽

Vol 31 (4) ◽

pp. 370-376 ◽

Cited By ~ 25

Author(s):

PETER MILLER ◽

KERRI COOMBER ◽

ANDERS SØNDERLUND ◽

STEPHEN MCKENZIE

Keyword(s):

Emergency Department ◽

Term Effect ◽

Long Term Effect

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Referral for psychological therapy of people with long term conditions improves adherence to antidepressants and reduces emergency department attendance: Controlled before and after study

Behaviour Research and Therapy ◽

10.1016/j.brat.2013.03.004 ◽

2013 ◽

Vol 51 (7) ◽

pp. 377-385 ◽

Cited By ~ 8

Author(s):

Simon de Lusignan ◽

Tom Chan ◽

Maria C. Tejerina Arreal ◽

Glenys Parry ◽

Kim Dent-Brown ◽

...

Keyword(s):

Emergency Department ◽

Psychological Therapy ◽

Long Term Conditions ◽

Emergency Department Attendance ◽

Before And After ◽

Before And After Study

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Long-term Effect of Optimized Sedation and Pain Management after Sudden Cardiac Arrest

The Open Cardiovascular Medicine Journal ◽

10.2174/1874192401509010091 ◽

2015 ◽

Vol 9 (1) ◽

pp. 91-95

Author(s):

Nadine Abanador-Kamper ◽

Judith Wolfertz ◽

Petra Thürmann ◽

Lars Kamper ◽

Melchior Seyfarth

Keyword(s):

Mechanical Ventilation ◽

Cardiac Arrest ◽

Length Of Stay ◽

Sudden Cardiac Arrest ◽

Ventilation Time ◽

Icu Length Of Stay ◽

Long Term Effect ◽

Before And After ◽

Mechanical Ventilation Time

Background and Aims: Appropriate use of sedatives and analgesics is essential to keep critically ill patients comfortable and to prevent prolonged mechanical ventilation time and length of stay in ICU. Aim of this study was to analyse the long-term effect of an algorithm-based individual analgesic-sedative protocol on mechanical ventilation time and ICU length of stay in critically ill patients after sudden cardiac arrest due to ST-elevated myocardial infarction. Subject and Methods: We examined a total of 109 patients before and after implementation of an algorithm-based sedation management. Our sedation protocol included individual defined sedation goals achieved by standardized sedation strategies. Mechanical ventilation time and ICU length of stay were analysed for three groups of patients: before and after the intervention and in the long-term follow-up. Results: We observed shorter median mechanical ventilation time and ICU length of stay in the interventional and longterm follow-up group compared to the standard-care group without statistical significance. Conclusion: Our results demonstrate a long-term reduction of mechanical ventilation time and ICU length of stay achieved by implementation of an individual sedation management. This suggests sedation guidelines as effective tools to reduce the mechanical ventilation time and ICU length of stay in patients after sudden cardiac arrest in ST-elevated myocardial infarction. Investigations with a larger patient number and higher statistical power are required to confirm these findings.

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The long term effect of a telemedicine intervention on heart failure admissions and length of stay

Journal of Cardiac Failure ◽

10.1016/s1071-9164(99)91642-1 ◽

1999 ◽

Vol 5 (3) ◽

pp. 78 ◽

Cited By ~ 1

Author(s):

Mary Bondmass ◽

Vinay Malhotra ◽

Gerard Castro ◽

Boaz Avitall

Keyword(s):

Heart Failure ◽

Length Of Stay ◽

Term Effect ◽

Long Term Effect

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Evaluation of the long-term effect of foldable capsular vitreous bodies in severe ocular rupture

International Journal of Ophthalmology ◽

10.18240/ijo.2021.12.19 ◽

2021 ◽

Vol 14 (12) ◽

pp. 1935-1940

Author(s):

Jin Deng ◽

◽

Rong-Le Zhou ◽

Tao Chen ◽

Jian-Zhou Wang ◽

...

Keyword(s):

Visual Acuity ◽

Anterior Chamber ◽

Vitreous Body ◽

Term Effect ◽

Subjective Feeling ◽

Light Perception ◽

Long Term Effect ◽

Before And After

AIM: To evaluate the long-term effect of foldable capsular vitreous body (FCVB) in the treatment of severe ocular rupture to provide a practical basis for clinical selection. METHODS: A total of 26 patients (26 eyes), 23 men and 3 women, with severe ocular rupture who underwent FCVB implantation between March 2018 and September 2018 were retrospectively analysed. All open ocular wounds located in zone III, with preoperative visual acuity grade IV and above (Snellen less than 4/200). The best corrected visual acuity (BCVA), intraocular pressure (IOP), cornea, anterior chamber, iris, lens, choroid, and retina were evaluated before and after the surgery. The subjective feeling and the location of FCVB were also assessed. RESULTS: The average age of the 26 patients was 36y (20-60y). Postoperative follow-up was from 10 to 14mo. At the end of follow up, BCVA was light perception (LP) in 10 cases, no light perception (NLP) in 13 cases, hand motions (HM) in 3 cases. IOP was 11±5 mm Hg. Corneal degeneration was in 3 cases and corneal endothelial dystrophy was in 7 cases. Shallow anterior chamber was in 8 cases and hyphema was in 8 cases. Organized membrane in the pupil was in 14 cases. Epiphora occurred in 3 cases. FCVB drainage tube exposed in 3 cases. All FCVBs were in their normal location and no rejection occurred. CONCLUSION: FCVB implantation is a long-term effective treatment and may provide a practical selection for severe ocular rupture.

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