scholarly journals Сardiac troponin I for assessment of myocardial damage and prediction of complications in cardiac surgery patients

2021 ◽  
pp. 15-19
Author(s):  
T. A. Sheshurina ◽  
V. V. Dorofeykov ◽  
T. V. Vavilova

The study analysed the level of troponin I (Tn) in the blood in patients with coronary artery disease after coronary artery bypass grafting in comparison with patients after aortic valve replacement surgery. The dynamics of troponin in the early postoperative period was studied, a parallelism was established between the occurrence of complications after surgery and the degree of myocardial damage. A new method has been developed for assessing the degree of intraoperative myocardial damage and the risk of complications using the «index of myocardial damage», the Tn level is determined twice after the operation, in the period up to 6 hours – Tn early and 12–24 hours later – Tn late, the index is calculated as the ratio of Tn late one to Tn early one. A correlation analysis of the «index» with other laboratory parameters was carried out, as a result of which no significant correlations were found, which indicates the absence of duplication and the significance of the developed indicator for assessing myocardial damage after cardiac surgery.

2021 ◽  
Vol 26 ◽  
pp. 4342
Author(s):  
D. V. Kuznetsov ◽  
A. A. Gevorgyan ◽  
V. V. Novokshenov ◽  
A. V. Kryukov ◽  
M. V. Polyaeva ◽  
...  

Extent of cardiac surgery aid has dropped significantly globally due to reallocation of health care resources due to COVID-19 pandemic.Aim. To evaluate the results of chosen management strategy for patients with coronary artery disease (CAD) and COVID-19 manifested in the early postoperative period after coronary artery bypass grafting.Material and methods. We present our experience of treating 19 patients with CAD and COVID-19 manifested in the early postoperative period after coronary artery bypass grafting. The main symptoms of COVID-19 in these patients were high-grade fever, severe general weakness, shortness of breath, and decreased blood oxygen saturation. Laboratory data showed significant increases in fibrinogen, C-reactive protein, ferritin, procalcitonin, and D-dimer levels. In all patients, according to the chest computed tomography, a picture of unilateral or bilateral multisegmental pneumonia in the form of ground-glass opacity areas was determined. The damaged lung area varied from 10% to 55%.Results. Patients were treated in accordance with the Russian guidelines, followed by transfer to continue therapy in specialized infectious diseases hospitals. Sixteen patients transferred to infectious diseases hospitals were subsequently discharged from in a satisfactory condition. Three patients died from various complications of COVID-19 (mortality rate, 16%).Conclusion. The development of new screening strategies, standard guidelines and protocols for the management of cardiac surgery patients in a pandemic will contribute to an earlier detection of COVID-19 and, accordingly, a timely change in treatment strategy.


1991 ◽  
Vol 38 (8) ◽  
pp. 1005-1011 ◽  
Author(s):  
Ronald D. Seegobin ◽  
Frank C. Goodland ◽  
Trevor H. Wilmshurst ◽  
James Johnston ◽  
Chris Wainwright ◽  
...  

Cardiac surgery is a specialty which has seen a range of major advancements and pioneering procedures within the last century. The second half of the twentieth century saw advancements in the correction of complex congenital cardiac defects, heart-lung transplantation, and surgery for ischaemic and valvular heart disease, and many of these procedures are now viewed as routine cardiac surgery. This chapter focuses on trials in coronary artery disease, coronary artery bypass grafts, valve replacement, and aortic stenosis, and the clinical trials which have influenced treatment decisions in these areas.


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